- Advanced Radiotherapy Techniques
- Radiomics and Machine Learning in Medical Imaging
- Brain Metastases and Treatment
- Head and Neck Cancer Studies
- Medical Imaging Techniques and Applications
- Advanced X-ray and CT Imaging
- Glioma Diagnosis and Treatment
- Salivary Gland Tumors Diagnosis and Treatment
- Nanoplatforms for cancer theranostics
- Cancer Immunotherapy and Biomarkers
- Radiopharmaceutical Chemistry and Applications
- Meningioma and schwannoma management
- Bladder and Urothelial Cancer Treatments
- Prostate Cancer Treatment and Research
- Urinary and Genital Oncology Studies
- Brain Tumor Detection and Classification
- Breast Cancer Treatment Studies
- Lung Cancer Diagnosis and Treatment
- Fibroblast Growth Factor Research
- Prostate Cancer Diagnosis and Treatment
- MRI in cancer diagnosis
University of Szeged
2019-2023
Studying the clinical utility of deep-inspirational breath-hold (DIBH) in left breast cancer radiotherapy (RT) was aimed at focusing on dosimetry and feasibility aspects.In this prospective trial all enrolled patients went through planning CT supine position under both DIBH free breathing (FB); whole irradiation (WBI) cases prone also taken. In 3-dimensional conformal (3DCRT) plans heart, anterior descending coronary artery (LAD), ipsilateral lung contralateral doses were analyzed. The...
To study the changes of glioblastoma multiforme during chemoradiotherapy (CRT) and to evaluate impact on dosimetry clinical outcomes.Forty-three patients underwent volumetric imaging-based replanning. Prognostic factors gross tumor volume in relation overall survival effect adaptive replanning were statistically analyzed.Patients with total removal, shorter time CRT (<27 days), methylated O-6 methylguanine DNA methyltransferase good performance status (>60%) had better survival. Tumor...
Background: Programmed cell death (PD)-1/PD-ligand 1 (PD-L1) inhibitors have made a breakthrough in the therapy of advanced urothelial bladder cancer (UBC). The impact Fibroblast Growth Factor Receptor 3 (FGFR3) mutation on effectiveness PD-L1 treatment remains still unclear. Objective: Our study aimed to investigate frequency FGFR mutations at different tumor stages, and their relation status survival. Methods: 310 patients with subsequent radical cystectomy were included retrospective over...
Introduction: The excellent soft-tissue contrast of magnetic resonance imaging (MRI) is appealing for delineation organs-at-risk (OARs) as it required radiation therapy planning (RTP). In the last decade there has been an increasing interest in using deep-learning (DL) techniques to shorten labor-intensive manual work and increase reproducibility. This paper focuses on automatic segmentation 27 head-and-neck 10 male pelvis OARs with methods based T2-weighted MR images. Method: proposed...
Background/Aim: Targeted therapy and immunotherapy, with additional stereotactic radiation (SRT) have revolutionized the management of metastatic malignant melanoma (mMM). We aimed to analyze effectiveness safety SRT determine its role in complex mMM. Patients Methods: treated 24 patients solitary metastasis, 15 oligometastatic disease one multiple metastases. The primary endpoint was investigate possible effect radiotherapy for lesions on patients' survival taking systemic into...
Introduction Prostate-specific membrane antigen (PSMA) is a transmembrane protein that may be expressed on the surface of prostate cancer (PC) cells. It enables more sensitive and specific diagnosis PC, compared to conventional anatomical imaging. Aim The integration PSMA-based imaging in personalized radiotherapy PC patients evaluation its impact target volume definition if stereotactic body (SBRT) planned for locally recurrent or oligometastatic disease. Patients methods data from 363...