A5013995736- Advanced Radiotherapy Techniques
- Boron Compounds in Chemistry
- Radiation Therapy and Dosimetry
- Glioma Diagnosis and Treatment
- Brain Metastases and Treatment
- Radiopharmaceutical Chemistry and Applications
- Radiomics and Machine Learning in Medical Imaging
- Medical Imaging Techniques and Applications
- Nuclear Physics and Applications
- Lung Cancer Diagnosis and Treatment
- Effects of Radiation Exposure
- Breast Cancer Treatment Studies
- Head and Neck Cancer Studies
- Lung Cancer Treatments and Mutations
- Digital Radiography and Breast Imaging
- Boron and Carbon Nanomaterials Research
- Advances in Oncology and Radiotherapy
- Pharmacological Effects and Toxicity Studies
- Neuroscience and Neuropharmacology Research
- Radiation Effects and Dosimetry
- Advanced MRI Techniques and Applications
- Prostate Cancer Diagnosis and Treatment
- Radiation Dose and Imaging
- Gastric Cancer Management and Outcomes
- Nanoplatforms for cancer theranostics
University of Szeged
2015-2024
ELI-HU Research and Development Non-Profit
2016-2023
Semmelweis University
2018-2020
University of Pecs
2008
OncoTherapy Science (Japan)
2006
University of Kapsovar
2004-2005
Essen University Hospital
1998-2003
University of Duisburg-Essen
1999-2001
Klinik und Poliklinik für Strahlentherapie und Radioonkologie
2001
Universitätsklinik für Strahlentherapie
2001
Based on previous observations a potential resort in the therapy of particularly radioresistant glioma would be its treatment with unsaturated fatty acids (UFAs) combined irradiation. We evaluated effect different UFAs (arachidonic acid (AA), docosahexaenoic (DHA), gamma-linolenic (GLA), eicosapentaenoic (EPA) and oleic (OA)) human U87 MG cell line by classical biochemical end-point assays, impedance-based, real-time cellular holographic microscopic analysis. further analyzed AA, DHA, GLA at...
The development from single shot basic laser plasma interaction research toward experiments in which repetition rated laser-driven ion sources can be applied requires technological improvements. For example, the case of radio-biological experiments, irradiation duration and reproducible controlled conditions are important for performing studies with a large number samples. We present advancements recent years at ATLAS 300 Garching near Munich since our last radiation biology experiment....
Radiosensitizing agents are capable of augmenting the damage ionizing radiation preferentially on cancer cells, thereby increasing potency and specificity radiotherapy. Metal-based nanoparticles have recently gathered ground in radio-enhancement applications, owing to their exceptional competence amplifying cell-killing effects irradiation. Our aim was examine radiosensitizing performance gold (AuNPs) chromatin-modifying histone deacetylase inhibitor suberoylanilide hydroxamic acid (SAHA)...
Laser wakefield acceleration (LWFA) offers a promising compact solution for the production of high and very energy electron (VHEE) beams, which have an ultrashort pulse duration with instantaneous dose rate small source size. These unique properties are radiobiological as well clinical interest. In this paper we focus on potential application repetition LWFA beams radiobiology radiotherapy. On basis particle-in-cell (PIC) Monte Carlo simulations propose that, using commercially available 1...
IntroductionDeep-inspirational breath hold (DIBH) is an option for heart protection in breast radiotherapy; we intended to study its individual benefit.Materials and Methods3DCRT treatment planning was performed a cohort of 103 patients receiving radiotherapy the whole (WBI)/chest wall (CWI) ± nodal regions (NI) both under DIBH free breathing (FB) supine position, WBI only cases prone (n = 45) too. A series patient-related dosimetry parameters were analyzed.ResultsThe technique provided...
The increasing use of proton radiotherapy during the last decade and rising number long-term survivors has given rise to a vital discussion on potential effects normal tissue. So far, deviations from clinically applied generic RBE (relative biological effectiveness) 1.1 were only obtained by in vitro studies, whereas indications vivo trials clinical studies are rare. In present work, wildtype zebrafish embryos (Danio rerio) used characterize plateau mid-SOBP (spread-out Bragg peak) radiation...
Meningiomas are usually slow growing, well circumscribed intracranial tumors. In symptom-free cases observation with close follow-up imaging could be performed. Symptomatic meningiomas surgically removed and/or treated radiotherapy. The study aimed to evaluate the volumetric response of at different time points after photon, proton, and a mixed photon carbon ion boost irradiation.In Group A 38 patients received proton therapy (median dose: 56 GyE in 1.8-2 daily fractions) or photon/carbon...
To detect the possible biochemical signs of inflammatory activation in peripheral circulation a rodent model hippocampus irradiation, and to examine effects L-alpha-glycerylphosphorylcholine (GPC) this experimental protocol.Anesthetized Sprague-Dawley rats were subjected 40 Gy cobalt irradiation both hemispheres hippocampus, with or without GPC treatment (50 mg/kg intravenously (i.v.), 5 min before n = 6, each). A third group (n 6) served as saline-treated control. Blood samples obtained 3 h...