A5033508622- Systemic Lupus Erythematosus Research
- Autoimmune and Inflammatory Disorders Research
- Renal Diseases and Glomerulopathies
- Inflammatory Myopathies and Dermatomyositis
- Vasculitis and related conditions
- Immunodeficiency and Autoimmune Disorders
- Inflammasome and immune disorders
- Adolescent and Pediatric Healthcare
- Childhood Cancer Survivors' Quality of Life
- Hematological disorders and diagnostics
- Dermatological and Skeletal Disorders
- Eosinophilic Disorders and Syndromes
- Diabetes and associated disorders
- Immune Cell Function and Interaction
- Hemoglobinopathies and Related Disorders
- Systemic Sclerosis and Related Diseases
- Skin Diseases and Diabetes
- Monoclonal and Polyclonal Antibodies Research
- Streptococcal Infections and Treatments
- Blood groups and transfusion
- Liver Diseases and Immunity
- Sarcoidosis and Beryllium Toxicity Research
- Tuberculosis Research and Epidemiology
- Osteomyelitis and Bone Disorders Research
- T-cell and B-cell Immunology
Universidade Federal da Bahia
2016-2025
Hospital Ana Nery
2011-2023
Rafael Advanced Defense Systems (Israel)
2010
Complexo Hospitalar Universitário Professor Edgard Santos
2009
Hospital São Rafael
2005-2007
Objective: To identify clusters of autoantibodies in a large cSLE population and to verify possible associations between different autoantibody the following variables: demographic data, cumulative clinical laboratory manifestations, disease activity, damage mortality. Methods: A cross-sectional study was performed 27 Pediatric Rheumatology University centers, including 912 patients. The frequencies seven selected (anti-dsDNA, anti-Ro/SSA, anti-La/SSB, anti-Sm, anti-RNP, aCL IgM and/or IgG...
We evaluated the prevalence and clinical associations of amenorrhea in 298 female juvenile systemic lupus erythematosus (JSLE) patients (ACR criteria) followed 12 Brazilian Paediatric Rheumatology centres. Amenorrhea was observed 35 (11.7%) with a mean duration 7.2 ± 3.6 months. The hormones were performed 32/35 none them had FSH LH levels above estradiol below normal range according to pubertal changes. JSLE younger (15.04 2.5 versus 17.8 3.1 years; P = 0.001), shorter period time between...
This study was to determine the prevalence and characteristics of osteoarticular manifestations on initial clinical presentation acute leukemias (ALs) childhood in state Bahia, Brazil.This retrospective assessed medical records 406 patients with AL from January 1995 December 2004.Acute lymphocytic leukemia (ALL) diagnosed 313 (77.1%) myeloid (AML), 93 (22.9%) patients, including 241 males (59.4%) 165 females (40.6%). Age ranged 9 months 15 years (average: 6.18 y). The most common presenting...
To describe the clinical and angiographic characteristics of Takayasu's arteritis in Brazilian children adolescents.A retrospective data collection was performed 71 adolescents followed 10 reference centers Pediatric Rheumatology. The evaluation carried out three different time points: from onset symptoms to diagnosis, 6th 12th month last visit.Of selected patients, 51 (71.8%) were girls. mean age diagnosis 9.2 (±4.2) years 1.2 (±1.4) years, respectively. At end study, 20 patients a state...
This study aimed to assess the safety and immunogenicity of quadrivalent human papillomavirus (qHPV) vaccination in childhood-onset systemic lupus erythematosus (cSLE) patients.Volunteer cSLE patients aged 9-20 years healthy controls (HC) were enrolled receive a two- or three-dose qHPV schedule from March 2014 2016. Study visits performed before first dose, one month after second third doses year dose. In each visit, disease activity adverse events following analyzed, serum sample was...
Objective The objective of this study was to compare demographic data, clinical/laboratorial features and disease activity at diagnosis in three different groups with distinct time intervals between onset signs/symptoms diagnosis. Methods A multicenter performed 1555 childhood-onset systemic lupus erythematosus (American College Rheumatology criteria) patients from 27 pediatric rheumatology services. Patients were divided into groups: A: short interval (<1 month); B: intermediate (≥1...
Anormalidades na função tireoidiana e presença de autoanticorpos da tireoide têm sido frequentemente descritas em pacientes com doenças reumatológicas autoimunes, como síndrome Sjögren, artrite reumatoide, lúpus eritematoso sistêmico esclerodermia. São limitados os dados sobre prevalência características clínicas tireoidite autoimune outras reumatológicas, tais febre reumática juvenil. Os autores revisaram as associações autoimunes endócrinas reumáticas, avaliando diversas faixas etárias...
Descrever as características clínicas e angiográficas da arterite de Takayasu em crianças adolescentes brasileiros. Foi feita coleta retrospectiva dados 71 acompanhados 10 centros brasileiros referência reumatologia pediátrica. A avaliação foi três tempos: início dos sintomas até o diagnóstico, do 6° ao 12° mês diagnóstico última consulta. Dos pacientes selecionados, 51 (71,8%) eram meninas. As médias idade tempo foram 9,2 anos (± 4,2) 1,2 1,4), respectivamente. No fim estudo, 20 estavam...
To evaluate if the 2019-European League Against Rheumatism/American College of Rheumatology (EULAR/ACR) criteria at diagnosis childhood-onset systemic lupus erythematosus (cSLE) are associated with higher rates early damage scored by Systemic Lupus International Collaborating Clinics/American (SLICC/ACR) Damage Index (SDI).This retrospective multicenter study included 670 cSLE patients ≤5 years disease duration. All fulfilled both 2019-EULAR/ACR and 1997-ACR classification criteria. Total...
Objectives To identify associations between mortality in cSLE patients and their characteristics: clinical laboratory features, disease activity damage scores, treatment; to evaluate risk factors associated with cSLE; determine the most frequent causes of death this group patients. Methods We performed a multicenter retrospective cohort using data from 1,528 followed 27 pediatric rheumatology tertiary centers Brazil. Patients’ medical records were reviewed according standardized protocol,...
Descrever as características clínicas e a ocorrência de artrite atípica em crianças com diagnóstico febre reumática (FR) acompanhadas ambulatórios terciários Salvador, Bahia. Estudo descritivo, uma série casos, do quadro clínico inicial ou recorrência 41 FR. Dos pacientes estudados (n=41), 61% eram sexo masculino; média idade 9,2 anos no momento entre 5 16 anos. Artrite esteve presente 75,6% dos pacientes; cardite 75,6%; coreia 31,7%; eritema marginado 14,6% nódulos subcutâneos 4,9%. Um...
To describe the clinical characteristics and occurrence of atypical arthritis in children diagnosed with rheumatic fever (RF) followed tertiary care clinics Salvador, Bahia, Brazil. A descriptive study a case series, initial presentation, recurrence 41 RF. Of patients studied (n=41), 61% were male, mean age 9.2 years, at diagnosis between 5 16 years. Arthritis was present 75.6% patients; carditis 75.6%; chorea 31.7%; erythema marginatum 14.6%; subcutaneous nodules 4.9%. An pattern observed...
<h3>Background:</h3> Patients with immune-mediated rheumatic diseases (IMRD) undergoing immunosuppressive treatment are at greater risk of infection. Infectious one the main causes death in this group patients. Although vaccination impacts reducing incidence infections, vaccine coverage general population Brazil has been falling over years. <h3>Objectives:</h3> To present preliminary results on influenza and pneumococcal (PCV10/13 PPV23) patients juvenile IMRD Brazil. <h3>Methods:</h3> This...