A5011881769- Total Knee Arthroplasty Outcomes
- Osteoarthritis Treatment and Mechanisms
- Knee injuries and reconstruction techniques
- RNA Interference and Gene Delivery
- Advanced Sensor and Energy Harvesting Materials
- Mesenchymal stem cell research
- Cardiac tumors and thrombi
- Plant Stress Responses and Tolerance
- Food Quality and Safety Studies
- Hip disorders and treatments
- Musculoskeletal synovial abnormalities and treatments
- Ginseng Biological Effects and Applications
- Shoulder Injury and Treatment
- Kruppel-like factors research
- RNA regulation and disease
- Vascular Malformations and Hemangiomas
- Sports injuries and prevention
- Skin Protection and Aging
- Sarcoma Diagnosis and Treatment
- Nuclear Receptors and Signaling
- Fungal Plant Pathogen Control
- Antioxidant Activity and Oxidative Stress
- Blood properties and coagulation
- Obstructive Sleep Apnea Research
- Neuroscience and Neural Engineering
Seoul National University
2009-2023
Kyung Hee University
2011-2016
Gyeongnam National University of Science and Technology
2014
Gyeongsangnam-do Agricultural Research and Extension Services
2014
Seoul National University Hospital
2009
Evidence for beneficial effects of squalene on ultraviolet (UV)-induced photoageing the skin is lacking.To investigate whether supplementation improves signs and molecular markers in human vivo.In total, 40 female volunteers aged > 50 years received two different doses [13.5 g/day (low-dose group) 27 (high-dose group)] 90 days. At baseline at completion study, facial wrinkles were measured using replicas. Skin samples taken to compare type I procollagen matrix metalloproteinase 1 mRNA levels...
Transglutaminase 2 (TG2) is a multifunctional enzyme that exhibits transamidase, GTPase, kinase, and protein disulfide isomerase (PDI) activities. Of these, transamidase-mediated modification of proteins regulates apoptosis, differentiation, inflammation, fibrosis. TG2 highly expressed in mesenchymal stem cells (MSCs) compared with differentiated cells, suggesting role specific for MSC characteristics. In this study, we report new function the regulation redox homeostasis. During vitro...
도라지는 초롱꽃과에 속하는 채소용 또는 약용으로 그 생산량이 해마다 증가하는 추세에 있다. 특히 국내의 경남지역에서는 토종도라지의 보존과 육성을 위한 정책을 추진하고 있고 도라지의 단가도 급등함에 따라 재배면적이 크게 증가하였다. 본 연구에서는 토종 순계를 보존하기 조직배양 기술의 확립과 함께 분자생물학적 기술을 이용한 판별 개발하기 기초연구를 수행하였다. 먼저 경남지역과 충남아산시 등의 야산에서 채종하여 수 십년간 자가 재배하여온 농가에서 수집한 종자를 중심으로 5종의 primer를 이용하여 RAPD분석을 수행한 결과 총 48개의 밴드를 생산하였으며, 이중 21개 밴드는 다형성을 보이는 밴드로 40.3%의 나타내었다. primer HD3는 13개의 밴드 중 10개가 계통간 보여서 76.9%의 높은 다형성빈도를 보였다. 향후 핵 DNA 보다는 핵외 DNA를 SNP 마커의 확보 등 보다 진보된 보완연구가 수행되어야 할 것으로 사료되었다. The total production...
Carney complex (CNC) is an autosomal dominant hereditary or sporadic multiple neoplastic syndrome that shows variable clinical symptoms. Generally, CNC appears as skin pigmentation, cardiac cutaneous myxomas, and endocrine tumours. We performed extensive evaluation of 9 individuals within 1 family in whom was suspected. Among them, 5 had with various manifestations. also mutational analysis suspected genes these patients. Although all patients were members the same family, CNC-related...