A5048010658- Urinary Bladder and Prostate Research
- Health, Environment, Cognitive Aging
- Lung Cancer Diagnosis and Treatment
- CNS Lymphoma Diagnosis and Treatment
- Epigenetics and DNA Methylation
- Total Knee Arthroplasty Outcomes
- Hepatocellular Carcinoma Treatment and Prognosis
- Effects and risks of endocrine disrupting chemicals
- Lung Cancer Treatments and Mutations
- Hormonal and reproductive studies
- Cancer Treatment and Pharmacology
- Gallbladder and Bile Duct Disorders
- Gastric Cancer Management and Outcomes
- Endometrial and Cervical Cancer Treatments
- Facial Nerve Paralysis Treatment and Research
- Knee injuries and reconstruction techniques
- Signaling Pathways in Disease
- HER2/EGFR in Cancer Research
- GABA and Rice Research
- Radiation Therapy and Dosimetry
- PI3K/AKT/mTOR signaling in cancer
- Breast Cancer Treatment Studies
- Brain Metastases and Treatment
- Head and Neck Cancer Studies
- Plant Gene Expression Analysis
Seoul National University
2006-2024
Health Insurance Review and Assessment Service
2021-2023
Seoul National University Hospital
2007-2020
Armed Forces Capital Hospital
2017
Boramae Medical Center
2015
Union Hospital
2011
81th Hospital of PLA
2011
Chang Gung Memorial Hospital
2011
Khon Kaen University
2011
Keimyung University
2007-2010
SUMMARY Drought is a major abiotic stress that severely affects cereal production worldwide. Although several genes have been identified enhance the ability of rice to withstand drought stress, further research needed fully understand molecular mechanisms underlying response stress. Our study showed overexpression DNA binding with one finger 12 ( OsDof12 ) enhances tolerance Rice plants overexpressing ‐OE) displayed significantly higher than parental japonica “Dongjin”. Transcriptome...
Sojung Han, Do Young Kim, Ho Yeong Lim, Jung-Hwan Yoon, Baek-Yeol Ryoo, Yujeong Kookhee Bo Yeon So Yi, Dong-Sook Do-Yeon Cho, Jina Yu, Suhyun and Joong-Won Park. Gut Liver -0001;0:. https://doi.org/10.5009/gnl220406
요양급여 적정성 평가의 성과와 과제The Health Insurance Review and Assessment Service (HIRA) has implemented the National Quality Program (NQAP) to improve quality of care.Beginning with five items including a pharmaceutical benefit in 2001, NQAP been expanded measuring 35 347 indicators as 2021.The results have publicly disclosed linked Value Incentive Healthcare Evaluation Grant Initiative that is designed support improvement care.The experience from implementing provides three implications for achieving...
160 Background: In Asia, where hepatitis B is very common, patients often present with locally advanced or metastatic hepatocellular carcinoma (HCC), and their prognosis poor. The EACH study was designed to evaluate the efficacy safety of FOLFOX4 vs. doxorubicin as palliative systemic chemotherapy in HCC. Methods: open-label, randomized, multicenter phase III conducted 371 China, Taiwan, Korea Thailand, who had HCC were ineligible for resection. Patients randomized 1:1 receive either...
670 Background: Bcl-2 is an anti-apoptotic marker and regulated by hormonal receptor pathways in breast cancer. We performed this study to assess the prognostic significance of ER, PR, p53, c-erbB2, bcl-2, Ki-67, EGFR as a for relapse cancer patients who received same adjuvant therapy single institution. Methods: A cohort 154 curatively resected had 4 lymph nodes or more doxorubicin cyclophosphamide followed paclitaxel (AC/T) chemotherapy was analyzed clinicopathologic characteristics...
It is well known that short cervix at mid-pregnancy a risk factor for spontaneous preterm birth in both singleton and twin gestations. Recent evidence also suggests long was predictor of the Caesarean delivery gestation (New Engl J Med 2008;358:1346–53). The purpose this study to determine whether associated with an increased pregnant women. We enrolled 754 women whose cervical length measured by transvaginal ultrasonography delivered our institution. Cases (cervical <15 mm) were excluded....
Background: CTLA-4Ig is regarded as an inhibitory agent of the T cell proliferation via blocking costimulatory signal which essential for full activation. To improve applicability, we developed CTLA-4Ig-CTKC in c-terminal lysine had been replaced by cysteine through single amino acid change. By changing acid, could be directly conjugated with liposome without further modification right orientation increasing chance binding to their ligands. Materials and methods: The mutation c-terminus was...
16069 Background: This is an interim report of a prospective multicenter phase II trial to evaluate 2-year disease free survival rate, toxicity, overall rate and recurrence in high-risk endometrial cancer patients who received concurrent chemoradiotherapy after staging operation. Methods: Thirty four with from 17 medical centers Korea have enrolled the study. The cell types were all endometrioid type they had no prior chemotherapy. They either stage III or IV operation including total...
Background: Exposure to endocrine-disrupting chemicals (EDC) may affect neurocognitive development in exposed individuals and/or offspring. Objectives: We aimed investigate the gene-environment interactions on associations between prenatal and postnatal exposure EDC children's a prospective cohort study. Methods: recruited midterm pregnant women 2008 2011 followed-up their children 2012-2019 (n=574 mother-child pairs). measured mothers' Bisphenol A (BPA), 3-Phenoxybenzoic acid (3-PBA),...
BACKGROUND: Epigenome-wide association studies (EWAS) frequently use linear regression analysis assuming that methylation levels are continuous variables between 0 and 1 with a unimodal distribution. While 2~5% of CpG sites known to have bimodal or trimodal (multimodal) distributions, such modality differences seldom considered in previous EWAS. OBJECTIVES: We developed novel EWAS model which takes the distribution into account, namely "methylation distribution-specific (MDS)-EWAS". METHODS:...
BACKGROUND: Epigenetic mechanisms have been suggested to play a role in the link between utero exposure bisphenol A (BPA) and pediatric obesity; however, there is little evidence regarding this humans. OBJECTIVES: We identified differentially methylated CpG sites among 594-targeted obesity-related (reported from previous epigenome-wide association studies) children aged 2 6 years, depending on prenatal BPA at second trimester. then evaluated relationship methylation status body mass index...