A5101733152- MicroRNA in disease regulation
- Cancer-related gene regulation
- Circular RNAs in diseases
- Endometriosis Research and Treatment
- Advanced Glycation End Products research
- RNA modifications and cancer
- S100 Proteins and Annexins
- Cardiac pacing and defibrillation studies
- Healthcare and Venom Research
- Liver Disease Diagnosis and Treatment
- Cervical Cancer and HPV Research
- Sleep and related disorders
- Traditional Chinese Medicine Studies
- Autophagy in Disease and Therapy
- Cancer-related molecular mechanisms research
- Pneumocystis jirovecii pneumonia detection and treatment
- Neuroinflammation and Neurodegeneration Mechanisms
- Protease and Inhibitor Mechanisms
- Cardiac Arrhythmias and Treatments
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Heme Oxygenase-1 and Carbon Monoxide
- Nuclear Receptors and Signaling
- Hematological disorders and diagnostics
- Signaling Pathways in Disease
- Ubiquitin and proteasome pathways
Chinese People's Liberation Army
2024
Wuxi People's Hospital
2017-2021
Harbin Medical University
2014-2019
Fourth Affiliated Hospital of Harbin Medical University
2018-2019
Wenzhou Medical University
2017-2019
First Affiliated Hospital of Wenzhou Medical University
2017-2019
Southern Medical University
2017
Changhai Hospital
2016-2017
Second Military Medical University
2016-2017
Nanjing Medical University
2005-2017
Abstract Circular RNAs were recently identified as a novel type of noncoding RNAs. An increasing number reports have demonstrated their essential regulatory roles in various biological processes and human diseases, including cancer. However, the role circRNA cervical cancer (CC) remains largely unknown. In current study, we investigated physiological functions circ_0067934 during CC development progression. We found that was overexpressed tissues cell lines. Circ_0067934 upregulation...
Rheumatoid arthritis (RA) is a complex and not fully understood autoimmune disease associated with multijoint damage. The main effector cells, the synovial fibroblasts, are apoptosis resistant hyperplastic which indicate that autophagy level high in tissue. Real-time PCR, immunocytochemistry, western blotting were used this paper to study status of tissues obtained from RA OA patients at time joint replacement surgery. We further evaluated correlation between levels activity-associated serum...
Abstract Growing evidences have indicated that microRNAs (miRNAs) can regulate hepatitis B virus (HBV) expression and replication, playing crucial roles in the development of HBV infection. Until now, functional role mechanism miR-802 replication remain unknown. We was upregulated HBV-associated hepatocellular carcinoma (HCC) tissues compared with adjacent noncancerous samples. In addition, we showed SMARCE1 level downregulated HCC negatively related MARCE1 tissues. Moreover, upregulated,...
BACKGROUND This study was conducted to observe the influence of different time intervals between prior cervical conization and posterior hysterectomy on postoperative infection in female patients with intraepithelial neoplasia or cancer. MATERIAL AND METHODS Medical records 170 who underwent following November 2010 September 2016 at Zhenjiang 4th Hospital were reviewed. According interval conization, classified into 1-2-week, 4-5-week, 6-week groups. The outcomes 46 iodoform gauze inside...
High mobility group box-1 (HMGB1) is a proinflammatory, DAMP protein that participates in many pathological conditions. In this study, we evaluated the usability of CSF HMGB1 as biomarker for diagnosis tuberculous meningitis (TBM).A total 59 TBM patients and 169 control were included our study. samples obtained analyzed using commercial ELISA kit.The mean was 19.36 ng/ml (n = 59) versus 3.12 non-TB 30), 2.13 with extra neural tuberculosis 73), 1.06 ng/m controls 66). According to receiver...
Hepatocellular carcinoma (HCC) is one of the leading digestive malignancies, with a high metastasis and recurrence. The development rapid progression HCC involves numerous complex molecular cellular events. Therefore, developing effective methods for prevention treatment requires an improved understanding biological HCC. In our previous analysis tissue microarray data, BTB domain‑containing 3 (BTBD3) gene was upregulated in tissues, indicating that it may be cancer‑associated serve role...
Abstract To evaluate the feasibility of serum HMGB1, anti-HMGB1 antibodies, and HMGB1/anti-HMGB1 ratio as a diagnosis indicator initial clinical classification in patients with fever unknown origin (FUO). Ninety-four classical FUO ninety healthy controls were enrolled this study. The subjects’ data collected. concentration HMGB1 was detected by commercial ELISA kit, while antibodies an in-house built kit further confirmed immunoblotting. According to hospital on discharge, ninety-four...
Hepatocellular carcinoma (HCC) is one of the most important health problems in China.This study analyzed expression high-mobility group protein B1 (HMGB1) and inhibitor apoptosis protein-2 (c-IAP2) proteins HCC compared to paired para-tumor tissue samples assess association with pathogenesis progression.Sixty-eight were collected for Western blot, qRT-PCR immunohistochemical analyses HMGB1 c-IAP2.HMGB1 c-IAP2 highly expressed [85.3% (58/68) 82.4% (56/68), respectively] [32.3% 27.9%,...
Introduction: Insomnia, one of the most common mental disorders, not only affects quality life, but also damages physical and health. Therefore, it is very necessary to explore molecular mechanism insomnia find some suitable treatments. At present, methods using drugs treat insomnia are satisfactory due lack evidences side effects. Hence, development non-drug treatments particularly important. Tuina manipulations, a Chinese massage method, has achieved certain therapeutic effects on...