A5087633721- Saffron Plant Research Studies
- Drug-Induced Hepatotoxicity and Protection
- Adipokines, Inflammation, and Metabolic Diseases
- Chemotherapy-induced organ toxicity mitigation
- Genomics, phytochemicals, and oxidative stress
- Medicinal Plants and Bioactive Compounds
- Liver Disease and Transplantation
- Pharmacological Effects of Natural Compounds
- Renal Diseases and Glomerulopathies
- Drug Transport and Resistance Mechanisms
- Liver physiology and pathology
- Inflammasome and immune disorders
- Liver Disease Diagnosis and Treatment
- Vitamin C and Antioxidants Research
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Chronic Kidney Disease and Diabetes
- Advanced Glycation End Products research
- Flavonoids in Medical Research
- Chemotherapy-induced cardiotoxicity and mitigation
- Inflammatory Bowel Disease
- Cytokine Signaling Pathways and Interactions
- Heme Oxygenase-1 and Carbon Monoxide
- Natural product bioactivities and synthesis
- Nanoparticles: synthesis and applications
- Occupational and environmental lung diseases
Mansoura University
2015-2024
Cairo University
2022
Benha University
2014-2022
Ministry of Health and Population
2021
Bnai Zion Medical Center
1985
Ulcerative colitis (UC) is usually a mildly active disease; however, it can be associated with serious systemic complications. The current study was undertaken to evaluate the anti-ulcerogenic and coloprotective properties of crocin; major biologically ingredient saffron against experimentally-induced UC, by intracolonic instillation AA (AA). Rats received either felodipine (3 mg/kg) or crocin (20 orally for 8 successive days as protective curative therapies. Either remedy, significantly...
Diabetic nephropathy (DN) is a diabetic complication characterized by disruption of renal microvasculature, reactive oxygen species accumulation and increased inflammation, all which contribute to injury. Phenethyl isothiocyanate (PEITC) naturally occurring well known for its antioxidant anti-inflammatory effects, yet reno-preventive effects against DN has not been investigated. The current study looked into the in vivo reno-protective PEITC STZ-induced rats. (3, 10 30 mg/kg) was...
Diabetic nephropathy [DN] is one of the most prevalent microvascular complications diabetes mellitus [DM] and it considered a leading cause kidney failure. In this study calycosin, an isoflavone that constitutes major constituent in Radix Astragali with numerous pharmacological merits was investigated as reno-protective agent against DN also potential underlying mechanisms were investigated. Streptozotocin (STZ) (40 mg/kg) injected peritoneal cavity male Sprague-Dawely rats to induce DM. For...
Drug-induced hepatotoxicity is one of the most commonly encountered obstacles in field medical practice. Sodium valproate (VPA) among many drugs with reported hepatotoxic effects. Sulforaphane (SFN) a thiol compound found wide abundance cruciferous plants that has numerous therapeutic efficacies. The current investigation sheds light on potential hepatoprotective effect SFN against VPA-induced liver injury rats. Twice daily VPA (700 mg/kg, i.p.) for 7 days induced significant biochemical...
The world-wide increase in cancer incidence imposes a corresponding significant the use of chemotherapeutic agents. Nephrotoxicity is side effect frequently encountered with cyclophosphamide (CP), which also well-known to cause acute and chronic lung toxicities. current study focuses on evaluation potential protective efficacy tranilast against subacute CP-induced kidney injuries male Swiss Albino mice. Intraperitoneal CP significantly impaired oxidant/anti-oxidant balance increased...