- Pesticide Residue Analysis and Safety
- Mycotoxins in Agriculture and Food
- Enzyme Production and Characterization
- Insect and Pesticide Research
- Orthopaedic implants and arthroplasty
- Pesticide Exposure and Toxicity
- Enzyme Structure and Function
- Protein Structure and Dynamics
- Pharmaceutical and Antibiotic Environmental Impacts
- RNA and protein synthesis mechanisms
- Antibiotic Resistance in Bacteria
- Wheat and Barley Genetics and Pathology
- Heavy metals in environment
- Orthopedic Infections and Treatments
- Hip disorders and treatments
- Antibiotics Pharmacokinetics and Efficacy
- Biofuel production and bioconversion
- Pharmacological Effects and Assays
- Protein Hydrolysis and Bioactive Peptides
- Carcinogens and Genotoxicity Assessment
- Analytical chemistry methods development
- Collagen: Extraction and Characterization
- Agricultural safety and regulations
- Escherichia coli research studies
- Total Knee Arthroplasty Outcomes
Chinese Academy of Fishery Sciences
2012-2025
ZheJiang Academy of Agricultural Sciences
2014-2024
Qilu Normal University
2022-2024
Shandong University of Technology
2024
University of Science and Technology of China
2020-2024
Lanzhou University
2024
Ministry of Agriculture and Rural Affairs
2018-2024
Kunming University of Science and Technology
2022
Jiangsu Province Hospital
2021
Nanjing Medical University
2021
Antibiotics are widely used in the treatment of bacterial infections and as food additives livestock industry. The wide usage antibiotics causes residues animal products, like milk, eggs meat. A number studies have reported that antibiotic exist at high concentrations watercourses around world. Doxycycline (DH), oxytetracycline (OTCC) florfenicol (FF) three most commonly veterinary China. However, toxic effects DH, OTCC FF limited. In this study, six-moth-old healthy male adult zebrafish...
Pigs and chickens are the most common food animals that important vectors for spreading antimicrobial-resistant pathogens among humans. Limited systematic AMR monitoring of these animal origin bacteria had been reported, especially in developed areas China.
Community-wide blind prediction experiments such as CAPRI and CASP provide an objective measure of the current state predictive methodology. Here we describe a community-wide assessment methods to predict effects mutations on protein-protein interactions. Twenty-two groups predicted comprehensive saturation mutagenesis for two designed influenza hemagglutinin binders results were compared with experimental yeast display enrichment data obtained using deep sequencing. The most successful...
Wheat grains are susceptible to contamination with various natural mycotoxins including regulated and emerging mycotoxins. This study surveyed the presence of mycotoxins, such as deoxynivalenol (DON) zearalenone (ZEN), beauvericin (BEA), enniatins (ENNs ENA, ENA1, ENB, ENB1) Alternaria (i.e., alternariol monomethyl ether (AME), (AOH), tenuazonic acid (TeA), tentoxin (TEN), altenuene (ALT)) in wheat randomly collected from eight provinces across China 2021. The results revealed that each...
The emergence of carbapenem-resistant Enterobacteriaceae strains has posed a severe threat to public health in recent years. mobile elements carrying the New Delhi metallo-β-lactqtamase (NDM) gene have been regarded as major mechanism leading rapid increase isolated from clinics and animals.We describe an NDM-5-producing Escherichia coli strain, ECCRA-119 (sequence type 156 [ST156]), poultry farm Zhejiang, China. is multidrug-resistant (MDR) isolate that exhibited resistance 27 antimicrobial...
Antimicrobial resistance (AMR) may lead to worldwide epidemics through human activities and natural transmission, posing a global public safety threat. Colistin mediated by the mcr-1 gene is most prevalent among animal-derived Escherichia coli, mcr-1-carrying E. coli have been frequently detected in central-eastern China. However, with AMR prevalence of Qinghai Plateau rarely investigated. Herein, 375 stool samples were collected from 13 poultry farms Province 346 strains isolated, which...
The first luciferase from Antarctic krill (LAK) was cloned and successfully expressed in Escherichia coli BL21(DE3). LAK exhibits the unique ability to emit bright violet fluorescence at an emission wavelength of 350 nm, which represents lowest reported bioluminescence for luciferases. However, its low thermal stability poses a limitation broader application. In this study, we employed rational design approach introduce three pairs artificial disulfide bonds into LAK. Circular dichroism (CD)...
Cold-adapted alginate lyases have unique advantages for oligosaccharide (AOS) preparation and brown seaweed processing. Robust cold-adapted are urgently needed industrial applications. In this study, a lyase-producing strain Vibrio sp. W2 was screened. Then, the gene ALYW201 cloned from expressed in food-grade host, Yarrowia lipolytica. The secreted Alyw201 showed activity of 64.2 U/mL, with molecular weight approximate 38.0 kDa, specific 876.4 U/mg. performed highest at 30 °C, more than 80%...
Deoxynivalenol (DON) and emerging Alternaria toxins often co-occur in cereal-based products, but the current risk assessment is commonly conducted for only one type of mycotoxin at a time. Compared to adults, infants young children are more susceptible mycotoxins through food consumption, especially with products which main source exposure. This study aimed perform probabilistic combined exposure DON three major toxins, namely including alternariol monomethyl ether (AME), (AOH), tenuazonic...
Abstract A rapid and sensitive method was developed validated for citrinin determination in red fermented rice products by liquid chromatography tandem mass spectrometry (LC‐MS/MS) under the selected reaction monitoring mode. Sample preparation especially focused, quantitative methods of LC‐MS/MS high‐performance with fluorescence detection (HPLC‐FLD) were compared. In samples, limit 1.0 μg/kg compared to 250 HPLC‐FLD, quantification 3.0 825 HPLC‐FLD. High correlation coefficient obtained (...