- Acute Ischemic Stroke Management
- Atrial Fibrillation Management and Outcomes
- Venous Thromboembolism Diagnosis and Management
- Cerebrovascular and Carotid Artery Diseases
- Traumatic Brain Injury and Neurovascular Disturbances
- Cardiac Arrhythmias and Treatments
- Infective Endocarditis Diagnosis and Management
- Intracranial Aneurysms: Treatment and Complications
- Dementia and Cognitive Impairment Research
- Gastroesophageal reflux and treatments
- Pharmacological Effects and Toxicity Studies
- Epilepsy research and treatment
- Dysphagia Assessment and Management
- Central Venous Catheters and Hemodialysis
- Gut microbiota and health
- Diverticular Disease and Complications
- Influenza Virus Research Studies
- Mechanical Circulatory Support Devices
- Emergency and Acute Care Studies
- Sepsis Diagnosis and Treatment
- Blood Coagulation and Thrombosis Mechanisms
- Neurological Disorders and Treatments
- Acute Myocardial Infarction Research
- Intracerebral and Subarachnoid Hemorrhage Research
- Cardiovascular Effects of Exercise
Cornell University
2018-2020
Weill Cornell Medicine
2018-2020
MIND Research Institute
2018-2020
Cincinnati Children's Hospital Medical Center
2020
Objective To determine whether cerebrovascular risk factors are associated with subsequent diagnoses of Parkinson disease, and these associations similar in magnitude to those Alzheimer disease. Methods This was a retrospective cohort study using claims data from 5% random sample Medicare beneficiaries 2008 2015. The exposures were stroke, atrial fibrillation, coronary hyperlipidemia, hypertension, sleep apnea, diabetes mellitus, heart failure, peripheral vascular chronic kidney obstructive...
Background Mobile stroke units (MSUs) reduce time to intravenous thrombolysis in acute ischemic stroke. Whether this advantage exists densely populated urban areas with many proximate hospitals is unclear. Methods and Results We evaluated patients from the METRONOME (Metropolitan New York Stroke) registry suspected who were transported by a bi-institutional MSU operating Manhattan, York, October 2016 September 2017. The comparison group included our via conventional ambulance for during same...
Background and Purpose- There has been a recent sharp rise in opioid-related deaths the United States. Intravenous opioid use can lead to infective endocarditis (IE) which result stroke. are scant data on trends this neurological complication of abuse. We hypothesized that increasing abuse led higher incidence stroke associated with IE use. Methods- used 1993 2015 releases National Inpatient Sample validated International Classification Diseases, Ninth Revision, Clinical Modification codes (...
Background Black individuals in the United States experience higher rates of ischemic stroke than other racial groups but have lower clinically apparent atrial fibrillation ( AF ). It is unclear whether blacks truly less or simply more undiagnosed . Methods and Results We performed a retrospective cohort study using inpatient outpatient claims from 2009 to 2015 for 5% nationally representative sample Medicare beneficiaries. included patients aged ≥66 years with at least 1 documented Current...
<b><i>Background:</i></b> In 2013, investigators from A Randomized Trial of Unruptured Brain Arteriovenous Malformations (AVM; ARUBA) reported that interventions to obliterate unruptured AVMs caused more morbidity and mortality than medical management. <b><i>Objective:</i></b> We sought determine whether for AVM decreased after publication ARUBA results. <b><i>Methods:</i></b> used the Nationwide Readmissions Database...
Background Sex differences have been found in stroke risk factors, incidence, treatment, and outcomes. There are conflicting data on whether diagnostic evaluation for may differ between men women. Methods Results We performed a retrospective cohort study using inpatient outpatient claims 2008 2016 from nationally representative 5% sample of Medicare beneficiaries. included patients ≥65 years old hospitalized with ischemic stroke, defined by International Classification Diseases, Ninth...
Background and Purpose: Recent studies suggest that alteration of the normal gut microbiome contributes to atherosclerotic burden cardiovascular disease. While many gastrointestinal diseases are known cause disruption in humans, clinical impact on subsequent cerebrovascular disease remains unknown. We conducted an exploratory analysis evaluating relationship between ischemic stroke. Methods: performed a retrospective cohort study using claims 2008 2015 from nationally representative 5%...
Background and Purpose— It is uncertain whether heart transplantation decreases the risk of stroke. The objective our study was to determine associated with a decreased subsequent stroke among patients failure awaiting transplantation. Methods— We performed retrospective cohort using administrative data from New York, California, Florida between 2005 2015. Individuals were identified previously validated International Classification Diseases, Ninth Revision, Clinical Modification diagnosis...
Among patients with status epilepticus, we sought to determine the rate of endotracheal intubation, identify physician specialties responsible for and characterize trend in use intubation over last 20 years.We performed a cross-sectional study using data from 2 sources. First, used inpatient claims between 2009 2015 nationally representative 5% sample Medicare beneficiaries. Patients epilepticus were identified International Classification Diseases, 9th Revision, Clinical Modification...
To test the hypothesis that thrombogenic atrial cardiopathy may be relevant to stroke-related racial disparities, we compared phenotypes between Black vs White patients with ischemic stroke.We assessed markers of in Greater Cincinnati/Northern Kentucky Stroke Study, a study stroke incidence population 1.3 million. We obtained ECGs and reports echocardiograms performed during evaluation 2010/2015 periods. Patients fibrillation (AF) or flutter (AFL) were excluded. Investigators blinded...
Background and Purpose- Allergic reactions, including anaphylaxis, can sometimes occur after intravenous thrombolysis in patients with acute ischemic stroke. However, it remains unclear whether stroke who receive thrombolytic agents face a higher risk of anaphylaxis than those do not thrombolytics. Methods- We performed retrospective cohort study using inpatient outpatient claims between 2008 2015 from nationally representative 5% sample Medicare beneficiaries. included were ≥65 years old...
Few data exist regarding the rate of inferior vena cava (IVC) filter retrieval among brain-injured patients.We conducted a retrospective cohort study using inpatient claims between 2009 and 2015 from nationally representative 5% sample Medicare beneficiaries. We included patients aged ≥65 years who were hospitalized with acute brain injury. The primary outcome was IVC at 12 months secondary outcomes association 30-day mortality 12-month freedom pulmonary embolism (PE). used Current...
Introduction: Case reports suggest that unruptured intracranial aneurysms may serve as a nidus for thrombus formation and downstream embolic stroke. However, few data exist to support an association between ischemic Hypothesis: Unruptured are more common ipsilateral than contralateral the side of cerebral infarction. Methods: We conducted within-subjects study among acute stroke patients prospectively enrolled in Cornell AcutE Stroke Academic Registry (CAESAR) who had magnetic resonance...
Introduction: Black individuals in the U.S. have a higher risk of ischemic stroke than whites but lower clinically apparent atrial fibrillation (AF), strong factor. It is unclear whether blacks truly less AF or simply more undiagnosed AF. Methods: We conducted retrospective cohort study using inpatient and outpatient claims from 2008-2015 nationally representative 5% sample Medicare beneficiaries. included patients ≥66 years old with black white race at least one documented Current...
Introduction: The increased risk of ischemic stroke in black versus white U.S. residents is not fully explained by known factors. Influenza has been implicated as a factor, and studies have shown that blacks less often receive influenza vaccination than whites. We investigated whether there an black-white racial disparity incidence during flu season. Methods: performed retrospective cohort study using inpatient outpatient claims between 2008-2015 from nationally representative 5% sample...
Background: There has been a recent sharp rise in opioid-related deaths the U.S. Intravenous opioid use can lead to infective endocarditis which result stroke. are scant data on trends this neurological complication of abuse. We investigated whether increasing abuse led higher incidence stroke from endocarditis. Methods: used 1993 2015 releases National Inpatient Sample and validated International Classification Diseases, 9 th Revision, Clinical Modification codes identify patients...
Introduction: Anaphylaxis has been reported as a potential adverse event after intravenous thrombolysis in patients with acute ischemic stroke, but the magnitude of risk remains unclear. Methods: We performed retrospective cohort study using inpatient and outpatient claims between 2008-2015 from nationally representative 5% sample Medicare beneficiaries. included who were ≥65 years old hospitalized defined by validated ICD-9-CM diagnosis codes. Our exposure was treatment an thrombolytic...
Introduction: Sex differences have been found in stroke risk factors, incidence, treatment, and outcomes. There are conflicting data on whether diagnostic evaluation for may differ between men women. Methods: We performed a retrospective cohort study using inpatient outpatient claims 2008-2015 from nationally representative 5% sample of Medicare beneficiaries. included patients who were ≥65 years old hospitalized with ischemic stroke, defined by validated ICD-9-CM diagnosis codes. providers’...