- Acute Ischemic Stroke Management
- Liver Disease Diagnosis and Treatment
- Intracerebral and Subarachnoid Hemorrhage Research
- Neurological Complications and Syndromes
- Liver Disease and Transplantation
- Cerebrovascular and Carotid Artery Diseases
- Intracranial Aneurysms: Treatment and Complications
- Atrial Fibrillation Management and Outcomes
- Venous Thromboembolism Diagnosis and Management
- Neurological Disorders and Treatments
- Stroke Rehabilitation and Recovery
- Cerebral Venous Sinus Thrombosis
- Long-Term Effects of COVID-19
- Moyamoya disease diagnosis and treatment
- COVID-19 Clinical Research Studies
- Cardiovascular Health and Risk Factors
- Folate and B Vitamins Research
- Neurosurgical Procedures and Complications
- Traumatic Brain Injury and Neurovascular Disturbances
- Liver Diseases and Immunity
- Smoking Behavior and Cessation
- Antiplatelet Therapy and Cardiovascular Diseases
- Blood Pressure and Hypertension Studies
- Neurological Disease Mechanisms and Treatments
- Dementia and Cognitive Impairment Research
Weill Cornell Medicine
2016-2024
Cornell University
2015-2024
MIND Research Institute
2016-2024
Presbyterian Hospital
2017-2024
Arcadia
2024
Cincinnati Children's Hospital Medical Center
2024
MUSC Hollings Cancer Center
2023
Massachusetts General Hospital
2023
Harvard University
2023
University of Calgary
2023
<h3>Importance</h3> It is uncertain whether coronavirus disease 2019 (COVID-19) associated with a higher risk of ischemic stroke than would be expected from viral respiratory infection. <h3>Objective</h3> To compare the rate between patients COVID-19 and influenza, illness previously stroke. <h3>Design, Setting, Participants</h3> This retrospective cohort study was conducted at 2 academic hospitals in New York City, York, included adult emergency department visits or hospitalizations March...
A large spectrum of neurologic disease has been reported in patients with coronavirus 2019 (COVID-19) infection. Our aim was to investigate the yield neuroimaging COVID-19 undergoing CT or MR imaging brain and describe associated findings.We performed a retrospective cohort study involving 2054 laboratory-confirmed presenting 2 hospitals New York City between March 4 May 9, 2020, whom 278 (14%) underwent either brain. All images initially received formal interpretation from neuroradiologist...
ObjectiveTo report four patients with coronavirus disease 2019 (COVID-19) who developed posterior reversible encephalopathy syndrome (PRES).MethodsPatient data was abstracted from medical records at Weill Cornell Medical Center.ResultsFour SARS-CoV-2 infection and PRES were identified. The patients' ages ranged 64 to 74 years, two women. All admitted the hospital acute respiratory distress requiring intensive care unit admission mechanical ventilation. diagnosed after persistent confusion,...
Mechanical thrombectomy helps prevent disability in patients with acute ischemic stroke involving occlusion of a large cerebral vessel. Thrombectomy requires procedural expertise and not all hospitals have the staff to perform this intervention. Few population-wide data exist regarding access mechanical thrombectomy.We examined for using discharge from calendar years 2016 2018 nonfederal emergency departments care across 11 US states encompassing 80 million residents. Facilities were...
We introduce a first order method for solving very large convex cone programs. The uses an operator splitting method, the alternating directions of multipliers, to solve homogeneous self-dual embedding, equivalent feasibility problem involving finding nonzero point in intersection subspace and cone. This approach has several favorable properties. Compared interior-point methods, first-order methods scale problems, at cost requiring more time reach high accuracy. other programs, our finds...
Metabolic, hormonal, and hemostatic changes associated with pregnancy loss (stillbirth miscarriage) may contribute to the development of cardiovascular disease (CVD) in adulthood. This study evaluated prospectively association between a history CVD cohort postmenopausal women. Postmenopausal women (77,701) were from 1993-1998. Information on baseline reproductive history, sociodemographic, risk factors collected. The associations 1 or 2 more miscarriages stillbirths occurrence using multiple...
Ventricular assist devices (VADs) have advanced the management of end-stage heart failure. However, these are associated with hemorrhagic and thrombotic complications, including stroke. We assessed incidence, risk factors, outcomes ischemic stroke after VAD placement.Using administrative claims data from acute care hospitals in California, Florida, New York 2005 to 2013, we identified patients who underwent placement, defined by International Classification Diseases, Ninth Revision, Clinical...
Background and Purpose— Cirrhosis—clinically overt, advanced liver disease—is associated with an increased risk of hemorrhagic stroke poor outcomes. We sought to investigate whether subclinical disease, specifically fibrosis, is clinical radiological outcomes in patients primary intracerebral hemorrhage. Methods— performed a retrospective cohort study using data from the Virtual International Stroke Trials Archive–Intracerebral Hemorrhage. included adult hemorrhage presenting within 6 hours...
Cirrhosis is associated with hemorrhagic and thrombotic extrahepatic complications. The risk of cerebrovascular complications less well understood.To investigate the association between cirrhosis various stroke types.We performed a retrospective cohort study using inpatient outpatient Medicare claims data from January 1, 2008, through December 31, 2014, for random 5% sample 1 618 059 beneficiaries older than 66 years.Cirrhosis, as defined by validated diagnosis code algorithm.The primary...
Background and Purpose— Carotid artery plaque with <50% luminal stenosis may be an underappreciated stroke mechanism. We assessed how many causes might reclassified after accounting for nonstenosing plaques high-risk features. Methods— included patients enrolled in the Cornell Acute Stroke Academic Registry from 2011 to 2015 who had anterior circulation infarction, magnetic resonance imaging of brain, angiography neck. High-risk was identified by intraplaque hemorrhage ascertained routine...
Background and Purpose— We sought to determine the long-term risk of seizures after stroke according age, sex, race, subtype. Methods— performed a retrospective cohort study using administrative claims from 2 complementary patient data sets. First, we analyzed all emergency department visits hospitalizations in California, Florida, New York 2005 2013. Second, evaluated inpatient outpatient nationally representative 5% random sample Medicare beneficiaries. Our consisted adults at time acute...
Objective We wanted to determine whether pregnancy is associated with cervical artery dissection. Methods performed a case–control study using claims data from all nonfederal emergency departments and acute care hospitals in New York Florida between 2005 2015. Cases were women 12–42 years of age hospitalized dissection, defined validated diagnosis codes for carotid/vertebral Controls primary renal colic. controls matched 1:1 on age, race, insurance, income, state, visit year. The exposure...
Background and Purpose: One-fifth of ischemic strokes are embolic undetermined source (ESUS). Their theoretical causes can be classified as cardioembolic versus noncardioembolic. This distinction has important implications, but the categories’ proportions unknown. Methods: Using data from Cornell Acute Stroke Academic Registry, we trained a machine-learning algorithm to distinguish non-cardioembolic strokes, then applied ESUS cases determine predicted proportion with an occult source. A...
Importance: Case series without control groups suggest that Covid-19 may cause ischemic stroke, but whether is associated with a higher risk of stroke than would be expected from viral respiratory infection uncertain. Objective: To compare the rate between patients and influenza, illness previously linked to stroke. Design: A retrospective cohort study. Setting: Two academic hospitals in New York City. Participants: We included adult emergency department visits or hospitalizations March 4,...
Background and Purpose— The rate of spinal cord infarction (SCI) after surgical or endovascular repair an aortic aneurysm dissection is unclear. Methods— Using administrative claims data, we identified adult patients discharged from nonfederal acute care hospitals in California, New York, Florida who underwent between 2005 2013. Patients with SCI diagnosed before the were excluded. Our primary outcome was during index hospitalization for repair. Descriptive statistics used to estimate crude...
Background and Purpose— We used a decision analysis approach to analyze triage strategies for patients with acute stroke symptoms while accounting prehospital large vessel occlusion (LVO) screening methods key time metrics. Methods— Our compared anticipated functional outcomes within the IV-tPA (intravenous tissue-type plasminogen activator) treatment window in mothership drip-and-ship frameworks. Key branches of model included eligibility, presence an LVO, endovascular therapy eligibility....