- Meningioma and schwannoma management
- Pituitary Gland Disorders and Treatments
- Glioma Diagnosis and Treatment
- Neurofibromatosis and Schwannoma Cases
- Long-Term Effects of COVID-19
- Radiopharmaceutical Chemistry and Applications
- Neuroendocrine Tumor Research Advances
- Adrenal and Paraganglionic Tumors
- Medical Imaging Techniques and Applications
- Neuroblastoma Research and Treatments
- COVID-19 Clinical Research Studies
- Dementia and Cognitive Impairment Research
- Acute Ischemic Stroke Management
- Brain Metastases and Treatment
- Radiation Dose and Imaging
- Infectious Encephalopathies and Encephalitis
- Radiomics and Machine Learning in Medical Imaging
- Machine Learning in Healthcare
- Radiology practices and education
- Medical Imaging and Analysis
- Health, Environment, Cognitive Aging
- Sarcoma Diagnosis and Treatment
- Lanthanide and Transition Metal Complexes
- Traumatic Brain Injury and Neurovascular Disturbances
- Cerebrospinal fluid and hydrocephalus
Cornell University
2019-2024
New York Hospital Queens
2020-2024
Presbyterian Hospital
2020-2024
NewYork–Presbyterian Hospital
2020-2024
Weill Cornell Medicine
2019-2024
Berkeley College
2024
University of California, Berkeley
2024
University of Colorado Hospital
2023
University of Colorado Denver
2023
Eaton (Taiwan)
2019
<h3>Importance</h3> It is uncertain whether coronavirus disease 2019 (COVID-19) associated with a higher risk of ischemic stroke than would be expected from viral respiratory infection. <h3>Objective</h3> To compare the rate between patients COVID-19 and influenza, illness previously stroke. <h3>Design, Setting, Participants</h3> This retrospective cohort study was conducted at 2 academic hospitals in New York City, York, included adult emergency department visits or hospitalizations March...
<h3>SUMMARY:</h3> Miller Fisher syndrome, also known as variant of Guillain-Barré is an acute peripheral neuropathy that can develop after exposure to various viral, bacterial, and fungal pathogens. It characterized by a triad ophthalmoplegia, ataxia, areflexia. syndrome has recently been described in the clinical setting novel coronavirus disease 2019 (COVID-19) without accompanying imaging. In this case, we report first presumptive case COVID-19–associated with MR imaging findings.
A large spectrum of neurologic disease has been reported in patients with coronavirus 2019 (COVID-19) infection. Our aim was to investigate the yield neuroimaging COVID-19 undergoing CT or MR imaging brain and describe associated findings.We performed a retrospective cohort study involving 2054 laboratory-confirmed presenting 2 hospitals New York City between March 4 May 9, 2020, whom 278 (14%) underwent either brain. All images initially received formal interpretation from neuroradiologist...
Meningiomas are the most common primary intracranial tumors, typically treated with surgery and adjuvant radiation in cases of subtotal resection and/or higher histopathologic grade. Contrast-enhanced magnetic resonance imaging (MRI) is gold standard for postoperative assessment treatment planning. However, MRI can have limited accuracy particularly presence posttreatment change. [68Ga]-DOTATATE a Positron Emission Tomography (PET) radiotracer targeting somatostatin receptor 2A (SSTR2A)....
Abstract Background Our purpose was to determine the utility of [68Ga]-DOTATATE PET/MRI in meningioma response assessment following radiosurgery. Methods Patients with prospectively underwent postoperative DOTATATE PET/MRI. Co-registered PET and gadolinium-enhanced T1-weighted MRI were employed for radiosurgery planning. Follow-up performed at 6–12 months post-radiosurgery. Maximum absolute standardized uptake value (SUV) SUV ratio (SUVRSSS) referencing superior sagittal sinus (SSS) blood...
Importance: Case series without control groups suggest that Covid-19 may cause ischemic stroke, but whether is associated with a higher risk of stroke than would be expected from viral respiratory infection uncertain. Objective: To compare the rate between patients and influenza, illness previously linked to stroke. Design: A retrospective cohort study. Setting: Two academic hospitals in New York City. Participants: We included adult emergency department visits or hospitalizations March 4,...
Meningiomas express high levels of somatostatin receptor 2 (SSTR2). SSTR2-targeted PET imaging with [68Ga]-DOTATATE can aid distinguishing residual meningioma from reactive changes in the postoperative setting. We present initial dosimetric analyses, acute events, and local control data utilizing PET/MRI-assisted target delineation for prospectively-treated intermediate-risk meningiomas.Twenty-nine patients underwent DOTATATE PET/MRI evaluation 2019. Eight 9 meningiomas met RTOG 0539...
Abstract Multiple approaches with [ 68 Ga]-DOTATATE, a somatostatin analog PET radiotracer, have demonstrated clinical utility in evaluation of meningioma but not been compared directly. Our purpose was to compare diagnostic performance different quantitative brain Ga]-DOTATATE PET/MRI analysis patients suspected recurrence and establish the optimal threshold for each method. Patients were imaged prospectively PET/MRI. Lesions classified as meningiomas post-treatment change (PTC), using...
While contrast-enhanced MR imaging is the criterion standard in meningioma diagnosis and treatment response assessment, gallium
Esthesioneuroblastoma (ENB), also known as olfactory neuroblastoma, is a rare sinonasal neuroectodermal malignancy with slow onset of symptoms, favorable 5-year survival, and propensity for delayed locoregional recurrence. Current treatment options include resection, adjuvant radiotherapy, and/or chemotherapy; however, because its rarity location, determining the optimal ENB has been challenging.ENBs strongly express somatostatin receptors (SSTRs), particularly SSTR2, providing molecular...
<h3>BACKGROUND AND PURPOSE:</h3> Skull base chordomas often demonstrate variable MR imaging characteristics, and there has been limited prior research investigating the potential clinical relevance of this variability. The purpose retrospective study was to assess prognostic implications signal intensity on standard techniques for biologic behavior skull chordomas. <h3>MATERIALS METHODS:</h3> Medical records were retrospectively reviewed 22 patients with pathologically confirmed Clinical...
Purpose To evaluate dynamic gallium 68 (68Ga) tetraazacyclododecane tetraacetic acid octreotate (DOTATATE) brain PET/MRI as an adjunct modality in meningioma, enabling multiparametric standardized uptake value (SUV) and Patlak net binding rate constant (Ki) imaging, to optimize static acquisition period. Materials Methods In this prospective study (ClinicalTrials.gov no. NCT04081701, DOMINO-START), 68Ga-DOTATATE PET/MRI–derived time-activity curves (TACs) were measured 84 volumes of interest...
Meningiomas, the most common primary intracranial tumor, are vascular neoplasms that express somatostatin receptor-2 (SSTR2). The purpose of this investigation was to evaluate if a relationship exists between tumor vascularity and SSTR2 expression, which may play role in meningioma prognostication clinical management. Gallium-68-DOTATATE PET/MRI with dynamic contrast-enhanced (DCE) perfusion prospectively performed. Clinical demographic patient characteristics were recorded. Tumor volumes...
We describe an extremely rare case of unilateral rete mirabile in a young woman and discuss its significance embryological development as well radiological aspects, differential diagnosis potential clinical implications.
This review examines the possible role for definitive embolization as a primary therapy intracranial meningiomas. Surgery or radiosurgery are currently considered standard of care most benign However, each these carries substantial risks. The perioperative mortality surgical resection, reported in large series, is between 3.7–9.4%; studies report similarly high rate new neurological deficits following surgery. complications from 2–16% and it may take months to years before improvement...
Paragangliomas are rare neuroendocrine tumors that result from the abnormal migration of neural crest progenitor cells, or paraganglia, during embryonic development. Paraganglia in head and neck migrate along a branchial mesoderm; therefore, paragangliomas may occur anywhere branchiomeric distribution. Head demonstrate number characteristic features, such as common anatomic locations, symptomatology, associated genetic mutations, appearance on multimodal imaging. Understanding these...