A5010768101- Neuroinflammation and Neurodegeneration Mechanisms
- Neurological Disease Mechanisms and Treatments
- Nitric Oxide and Endothelin Effects
- Acute Ischemic Stroke Management
- Traumatic Brain Injury and Neurovascular Disturbances
- Alzheimer's disease research and treatments
- Cerebrovascular and Carotid Artery Diseases
- Intracerebral and Subarachnoid Hemorrhage Research
- Neurological Disorders and Treatments
- Neuroscience and Neuropharmacology Research
- Renin-Angiotensin System Studies
- Neuroscience of respiration and sleep
- Dementia and Cognitive Impairment Research
- Mitochondrial Function and Pathology
- Eicosanoids and Hypertension Pharmacology
- Inflammatory mediators and NSAID effects
- Barrier Structure and Function Studies
- S100 Proteins and Annexins
- Venous Thromboembolism Diagnosis and Management
- Receptor Mechanisms and Signaling
- Immune Response and Inflammation
- Advanced MRI Techniques and Applications
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Neuroendocrine regulation and behavior
- Regulation of Appetite and Obesity
Cornell University
2016-2025
MIND Research Institute
2016-2025
Weill Cornell Medicine
2016-2025
University of Zagreb
2023
National Cerebral and Cardiovascular Center
2023
Washington University in St. Louis
2023
Landscape Research Group
2023
Authorised Association Consortium
2023
Faculty of 1000 (United States)
2023
Johns Hopkins Medicine
2017-2021
One in 3 individuals will experience a stroke, dementia or both. Moreover, twice as many have cognitive impairment short of either stroke dementia. The commonly used scales do not measure cognition, while criteria focus on the late stages impairment, and are heavily biased toward diagnosis Alzheimer disease. No agreed standards exist for identifying describing with particularly early stages, especially related to vascular factors, impairment.The National Institute Neurological Disorders...
<h3>Importance</h3> It is uncertain whether coronavirus disease 2019 (COVID-19) associated with a higher risk of ischemic stroke than would be expected from viral respiratory infection. <h3>Objective</h3> To compare the rate between patients COVID-19 and influenza, illness previously stroke. <h3>Design, Setting, Participants</h3> This retrospective cohort study was conducted at 2 academic hospitals in New York City, York, included adult emergency department visits or hospitalizations March...
Cyclo-oxygenase-2 (COX-2), a rate-limiting enzyme for prostanoid synthesis, is induced during inflammation and participates in inflammation-mediated cytotoxicity. Cerebral ischemia followed by an inflammatory reaction that plays role the evolution of tissue damage. We studied whether COX-2 after cerebral if so, such expression contributes to ischemic brain The middle artery was occluded rats, area sampled analysis 3–96 hr later. mRNA determined competitive reverse-transcription PCR....
Inducible nitric oxide synthase (iNOS), an enzyme that produces toxic amounts of oxide, is expressed in a number brain pathologies, including cerebral ischemia. We used mice with null mutation the iNOS gene to study role ischemic damage. Focal ischemia was produced by occlusion middle artery (MCA). In wild-type mice, mRNA expression post-ischemic begun between 24 and 48 hr peaked at 96 subsided 7 d after MCA occlusion. induction associated protein enzymatic activity. contrast, lacking did...
Abstract Increasing evidence recognizes Alzheimer's disease (AD) as a multifactorial and heterogeneous with multiple contributors to its pathophysiology, including vascular dysfunction. The recently updated AD Research Framework put forth by the National Institute on Aging–Alzheimer's Association describes biomarker‐based pathologic definition of focused amyloid, tau, neuronal injury. In response this article, here we first discussed that dysfunction is an important early event in...