- Heart Failure Treatment and Management
- Cardiovascular Health and Risk Factors
- Nutritional Studies and Diet
- Blood Pressure and Hypertension Studies
- Lipoproteins and Cardiovascular Health
- Obesity, Physical Activity, Diet
- Pharmaceutical Practices and Patient Outcomes
- Health Systems, Economic Evaluations, Quality of Life
- Cardiac Health and Mental Health
- Acute Myocardial Infarction Research
- Health disparities and outcomes
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Medication Adherence and Compliance
- Diet and metabolism studies
- Cardiovascular Function and Risk Factors
- Chronic Disease Management Strategies
- Atrial Fibrillation Management and Outcomes
- Acute Ischemic Stroke Management
- Sodium Intake and Health
- Pharmaceutical Economics and Policy
- Long-Term Effects of COVID-19
- HIV, Drug Use, Sexual Risk
- HIV/AIDS Research and Interventions
- Nutrition and Health in Aging
- Rheumatoid Arthritis Research and Therapies
University of Alabama at Birmingham
2016-2025
Alabama Department of Public Health
2017-2025
University of Alabama
2025
Cornell University
2017-2024
Presbyterian Hospital
2024
Rabin Medical Center
2023
Institute of Hydrology of the Slovak Academy of Sciences
2023
Johns Hopkins University
2020-2022
Johns Hopkins Medicine
2020
Weill Cornell Medicine
2017-2020
<h3>Importance</h3> Controlling blood pressure (BP) reduces the risk for cardiovascular disease. <h3>Objective</h3> To determine whether BP control among US adults with hypertension changed from 1999-2000 through 2017-2018. <h3>Design, Setting, and Participants</h3> Serial cross-sectional analysis of National Health Nutrition Examination Survey data, weighted to be representative adults, between 2017-2018 (10 cycles), including 18 262 aged years or older defined as systolic level 140 mm Hg...
The American College of Cardiology/American Heart Association (ACC/AHA) Pooled Cohort risk equations were developed to estimate atherosclerotic cardiovascular disease (CVD) and guide statin initiation.OBJECTIVE To assess calibration discrimination the in a contemporary US population.
Importance SARS-CoV-2 infection is associated with persistent, relapsing, or new symptoms other health effects occurring after acute infection, termed postacute sequelae of (PASC), also known as long COVID . Characterizing PASC requires analysis prospectively and uniformly collected data from diverse uninfected infected individuals. Objective To develop a definition using self-reported describe frequencies across cohorts, vaccination status, number infections. Design, Setting, Participants...
Acute kidney injury (AKI) independently predicts mortality in children and adults. Our understanding of the epidemiology AKI very LBW (VLBW) infants is limited to retrospective studies. After adjustment for demographics, comorbidities, interventions, with have decreased survival compared those without AKI. The study was conducted regional quaternary care NICU University Alabama at Birmingham. VLBW were followed prospectively classified into a serum creatinine (SCr)-based classification...
Variability of blood pressure (BP) across outpatient visits is frequently dismissed as random fluctuation around a patient's underlying BP.To examine the association visit-to-visit variability (VVV) systolic BP (SBP) and diastolic with cardiovascular disease (CVD) mortality outcomes.Prospective cohort study.Post hoc analysis ALLHAT (Antihypertensive Lipid-Lowering Treatment to Prevent Heart Attack Trial).25 814 participants.The VVV SBP was defined SD measurements obtained at 7 conducted from...
Background: Despite potential harm that can result from polypharmacy, real-world data on polypharmacy in the setting of heart failure (HF) are limited. We sought to address this knowledge gap by studying older adults hospitalized for HF derived REGARDS study (Reasons Geographic and Racial Differences Stroke). Methods: examined 558 aged ≥65 years with adjudicated hospitalizations 380 hospitals across United States. collected baseline assessment, medical charts HF-adjudicated hospitalizations,...
Individual cohort studies concur that the amyloidogenic V142I variant of transthyretin (TTR) gene, present in 3% to 4% US Black individuals, increases heart failure (HF) and mortality risk. Precisely defining carrier risk across relevant clinical outcomes estimating population burden disease are important given established emerging targeted treatments.
The prevalence of hypertension is higher among blacks than whites. However, inconsistent findings have been reported on the incidence middle-aged and older whites, limited data are available Hispanics Asians in United States. Therefore, this study investigated age-specific by ethnicity for 3146 participants from Multi-Ethnic Study Atherosclerosis. Participants, age 45 to 84 years at baseline, were followed a median 4.8 incident hypertension, defined as systolic blood pressure ≥140 mm Hg,...
<h3>Background</h3> The Dietary Approaches to Stop Hypertension (DASH) diet effectively reduces blood pressure. In observational studies, the association between diets consistent with DASH and risk of coronary heart disease stroke has been examined varying results. We hypothesized that would be associated a lower incidence failure (HF). <h3>Methods</h3> conducted prospective study in 36 019 participants Swedish Mammography Cohort who were aged 48 83 years without baseline HF, diabetes...
Current dietary recommendations for patients with heart failure (HF) are largely based on data from non-HF populations; evidence associations of patterns outcomes in HF is limited. We therefore evaluated Mediterranean and Dietary Approaches to Stop Hypertension (DASH) diet scores mortality among postmenopausal women HF. Women's Health Initiative participants were followed up the date hospitalization through death or last participant contact before August 2009. DASH calculated food-frequency...
Objective The risks of hospitalized infection associated with biologic agents used to treat rheumatoid arthritis (RA) are unclear. aim this study was determine whether the risk infections differed between specific RA. Methods In a retrospective cohort using Medicare data from 2006–2011 for all enrolled patients RA, new episodes treatment etanercept, adalimumab, certolizumab, golimumab, infliximab, abatacept, rituximab, and tocilizumab were identified. Patients required have received another...
<h3>Importance</h3> Although hospice use is increasing and patients in the US are increasingly dying at home, racial disparities treatment intensity end of life, including use, remain. <h3>Objective</h3> To examine differences between Black White end-of-life care a population sample with well-characterized causes death. <h3>Design, Setting, Participants</h3> This study used data from Reasons for Geographic Racial Differences Stroke (REGARDS) study, an ongoing population-based cohort...
To evaluate whether the risks of herpes zoster (HZ) differed by biologic agents with different mechanisms action (MOAs) in older rheumatoid arthritis (RA) patients.Using Medicare data from 2006-2011, among RA patients prior agent use and no history cancer or other autoimmune diseases, this retrospective cohort study identified new treatment episodes abatacept, adalimumab, certolizumab, etanercept, golimumab, infliximab, rituximab, tocilizumab. Followup started on initiation ended at any...
To compare the coronary heart disease risk among patients with rheumatoid arthritis (RA) initiating common biologic disease-modifying antirheumatic drugs of different mechanisms.We conducted a retrospective cohort study RA enrolled in Medicare, public health plan covering >90% US residents 65 years or older, from 2006 to 2012 who (1) initiated biologic, (2) had complete medical and pharmacy coverage for at least 12 months before initiation (3) were free time initiation. We compared incidence...
The use of statins increased among US adults with high coronary heart disease (CHD) risk after publication the 2001 cholesterol treatment guidelines.