A5009022714- Catalysis for Biomass Conversion
- Advanced Photocatalysis Techniques
- Mesoporous Materials and Catalysis
- Cancer-related molecular mechanisms research
- MicroRNA in disease regulation
- Innovative Microfluidic and Catalytic Techniques Innovation
- Supercapacitor Materials and Fabrication
- TiO2 Photocatalysis and Solar Cells
- Microfluidic and Bio-sensing Technologies
- Advanced Nanomaterials in Catalysis
- 3D Printing in Biomedical Research
- Nanomaterials and Printing Technologies
- Polyoxometalates: Synthesis and Applications
- Layered Double Hydroxides Synthesis and Applications
- Epigenetics and DNA Methylation
- Nanofabrication and Lithography Techniques
- Immune cells in cancer
- Chemical Synthesis and Reactions
- Circular RNAs in diseases
- Covalent Organic Framework Applications
- Autophagy in Disease and Therapy
- Surface Modification and Superhydrophobicity
- Cancer Mechanisms and Therapy
- Melanoma and MAPK Pathways
- Galectins and Cancer Biology
Linyi University
2018-2025
Northeast Normal University
1992-2024
Dalian Polytechnic University
2024
Yancheng Teachers University
2021-2024
Hunan Cancer Hospital
2015-2024
Central South University
2013-2024
Ningbo Institute of Industrial Technology
2023-2024
Chinese Academy of Sciences
2014-2024
Tsinghua University
2022
Detection Limit (United States)
2021
Abstract In the process of photocatalytic synthesis ammonia, kinetics carrier separation and transport, adsorption nitrogen, activation NN triple bond are key factors that directly affect efficiency converting nitrogen to ammonia. Here, we report a new strategy for anchoring MXene quantum dots (MXene QDs) onto surface ZnIn 2 S 4 by forming TiS bonds, which provide channel rapid transport charge carriers effectively extend lifespan photogenerated carriers. The unique distribution caused...
The 5-year survival rate for colorectal cancer is approximately 55 % because of its invasion and metastasis. epithelial-mesenchymal transition (EMT) one the well-defined processes during distant metastasis primary epithelial tumors. miR-429, a member miR-200 family microRNAs, was previously shown to inhibit expression transcriptional repressors ZEB1/delta EF1 SIP1/ZEB2, regulate EMT. In this study, we showed that miR-429 significantly downregulated in carcinoma (CRC) tissues cell lines. We...
Despite the overwhelming number of investigations on AKT, little is known about lncRNA AKT regulation, especially in GBM cells. RNA-binding protein immunoprecipitation assay (RIP) and RNA pulldown were used to confirm binding LINC00470 fused sarcoma (FUS). Confocal imaging, co-immunoprecipitation (Co-IP) GST assays detect interaction between FUS AKT. EdU assay, CCK-8 intracranial xenograft performed demonstrate effect malignant phenotype RT-qPCR Western blotting test pAKT. In this study, we...
The epigenetics and genomics of glioblastoma (GBM) are complicated. Previous reports indicate that ELFN2 is widely distributed in the cerebral cortex neurons, striatum, hippocampus cone granular cells. However, function mechanism ELFN2, particularly GBM, have rarely been explored. In this study, we identified as a new hypomethylation gene acts an oncogene GBM. promoted cell autophagy by interacting with AurkA eIF2α inhibiting activation AurkA. We also demonstrated aberrantly high expression...
In this work, a new technology using ECL as microscopy to parallel image miRNA-21 in single cancer cell was built. Phorbol-12-myristate-13-acetate (PMA) loaded gold nanocages (Au NCs) closed with DNA gate which could be recognized and opened by HeLa cell. PMA then released further induced cells produce reactive oxygen species (ROS; including O2-•, •OH H2O2 etc.). With coreactant luminol active material, imaging of intracellular obtained EMCCD. Moreover, ROS therapy photothermal (PPT) Au...
Microglia are immune cells within the central nervous system (CNS) closely linked to brain health and neurodegenerative diseases such as Alzheimer’s disease Parkinson’s disease. In response changes in surrounding environment, microglia activate change their state function. Several factors, example for circadian rhythm disruption development of diseases, influence activation. this review, we explore microglia’s function associated neural mechanisms. We elucidate that rhythms essential factors...
We present a double-inkjet printing method for the generation of picoliter droplet-in-oil arrays on planar substrates, efficiently addressing droplet evaporation issues without assistance humidifier or glycerol.
Tumor-associated macrophages (TAMs) constitute a major component of inflammatory cells in the glioblastoma multiforme (GBM) tumor microenvironment. TAMs have been implicated GBM angiogenesis, invasion, local recurrence and immunosuppression. Coagulation factor X (FX) is vitamin K-dependent plasma protein that plays role regulation blood coagulation. In this study, we first found FX was highly expressed positively correlated with TAM density human GBM. exhibited potent chemotactic capacity to...
Superwetting surfaces have attracted considerable attention in analytical fields due to their unique ability concentrate target analytes within evaporating droplets, characterized by a constant contact angle and centripetal mobile line. While previous studies underscored the resistance of superslippery coffee-ring effect, our research presents novel strategy that dynamically introduces effect on such for visual detection. By harnessing synergistic interaction between line properties surface,...
Nitrogen-doped carbon-based acidic ionic liquid hollow nanospheres, [C3N][SO3CF3]-HCSs (C3 = PrSO3H), with different particle sizes (100–900 nm) and shell thicknesses (5–25 as well interesting morphology-dependent porosity properties were successfully prepared via quaternary ammonization of nitrogen atoms nitrogen-doped carbon nanospheres by 1,3-propane sultone followed anion exchange trifluoromethanesulonic acid. The applied in selective conversion fructose (FOS) to promising fuel blends,...
Colorectal cancer (CRC) is a common malignant gastrointestinal cancer. Efforts for preventive and personalized medicine have intensified in the last decade with attention to novel forms of biomarkers. In present study, microRNA genetic analyses were performed tandem differential transcriptome profiling between primary tumors or without nodes distant metastases. Serial Test Cluster (STC) analysis demonstrated that 20 genes two microRNAs showed distinctive expression patterns associated tumor,...
A series of arenesulfonic acid functionalized ethyl-bridged organosilica hollow nanospheres, ArSO3H-Et-HNS, with different shell thicknesses (2–6 nm) were successfully fabricated by P123 and/or F127-directed sol–gel cocondensation route and carefully controlled molar composition the starting materials in synthetic gel. The ArSO3H-Et-HNS applied synthesis levulinic (LA) from hydrolysis furfuryl alcohol (FAL), influence experimental parameters including solvent nature, volume ratio...
Ectopic epigenetic mechanisms play important roles in facilitating tumorigenesis. Here, we first demonstrated that ANKDD1A is a functional tumor suppressor gene, especially the hypoxia microenvironment. directly interacts with FIH1 and inhibits transcriptional activity of HIF1α by upregulating FIH1. In addition, decreases half-life FIH1, glucose uptake lactate production, glioblastoma multiforme (GBM) autophagy, induces apoptosis GBM cells under hypoxia. Moreover, highly frequently...
As a well-characterized key player in various signal transduction networks, extracellular-signal-regulated kinase (ERK1/2) has been widely implicated the development of many malignancies. We previously found that Leucine-rich repeat containing 4 (LRRC4) was tumor suppressor and negative regulator ERK/MAPK pathway glioma tumorigenesis. However, precise molecular role LRRC4 ERK transmission is unclear.The interaction between ERK1/2 assessed by co-immunoprecipitation GST pull-down assays vivo...