A5090902825- Enzyme Structure and Function
- Protein Structure and Dynamics
- Peripheral Neuropathies and Disorders
- Myasthenia Gravis and Thymoma
- Amyotrophic Lateral Sclerosis Research
- Muscle activation and electromyography studies
- Inflammatory Myopathies and Dermatomyositis
- Respiratory Support and Mechanisms
- Peripheral Nerve Disorders
- Enzyme Production and Characterization
- Hemoglobin structure and function
- Nerve Injury and Rehabilitation
- Muscle Physiology and Disorders
- Cancer Diagnosis and Treatment
- Advanced MRI Techniques and Applications
- Mass Spectrometry Techniques and Applications
- Orthopedic Surgery and Rehabilitation
- Hereditary Neurological Disorders
- Ultrasound and Hyperthermia Applications
- Neuroscience and Neural Engineering
- Molecular Biology Techniques and Applications
- CNS Lymphoma Diagnosis and Treatment
- Education, Safety, and Science Studies
- Neurogenetic and Muscular Disorders Research
- Elbow and Forearm Trauma Treatment
Kobe University
2015-2025
Tokyo Institute of Technology
2012
Kobe University Hospital
2011
Mitaka Kohki (Japan)
1984
Noninvasive evaluation of respiratory function in patients with various neuromuscular disorders is important for predicting life expectancy.We performed B-mode ultrasonography (USG) and nerve conduction studies 37 (16 had amyotrophic lateral sclerosis; 11, myopathy; 10, neuropathy) 10 controls. USG the diaphragm was supine position using a linear probe over intercostal space at anterior axillary line. Diaphragm muscle thickness measured end-expiration. The amplitude compound action...
ABSTRACT Introduction/Aims Patients with myasthenia gravis (MG) often experience impairment of respiratory function. Some case reports have explored the diaphragmatic compound muscle action potential (DCMAP) amplitudes in patients MG using single‐stimulus phrenic nerve conduction studies. Herein, we aimed to investigate whether DCMAP amplitude correlated clinical severity and this improved treatment. Methods We retrospectively evaluated who underwent right patients' characteristics MG, as...
Many artificial intelligence approaches to muscle ultrasound image analysis have not been implemented on usable devices in clinical neuromuscular medicine practice, owing high computational demands and lack of standardised testing protocols. This study evaluated the feasibility using real-time texture differentiate between various pathological conditions.
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We aimed to evaluate differences in ultrasonographic nerve enlargement sites among typical chronic inflammatory demyelinating polyradiculoneuropathy (CIDP), distal CIDP, multifocal CIDP and motor neuropathy (MMN) a Japanese population. retrospectively reviewed medical records selected 39 patients (14 with 7 4 14 MMN) who underwent ultrasonography. Median ulnar cross-sectional areas (CSAs) were measured at the wrist, forearm, elbow, upper arm. CSA ratios for each calculated as:...
A 79-year-old woman who presented ptosis and dysphagia were admitted to our hospital. Anti-acetylcholine receptor antibodies anti-P/Q-type VGCC both positive. Electrophysiological examination showed postsynaptic pattern which supported myasthenia gravis. She did not meet the diagnostic criteria for Lambert-Eaton myasthenic syndrome (LEMS). In cases these coexist, careful electrophysiological evaluation is required diagnosis. addition, although have been specific LEMS, patients with represent...
症例は65歳の男性である．全身倦怠感が持続し，初発2カ月後より意識障害が緩徐に進行した．頭部MRIでは脳幹，前頭葉，側頭葉，基底核にFLAIR画像で高信号域をみとめ，Gdで増強されなかった．髄液中のEpstein-Barr virus（EBV）-DNA量の増加をみとめ，EBV感染がうたがわれた．アシクロビル投与に加えステロイドパルスを施行したが，効果は乏しく意識レベルはしだいに低下し，第146病日に死亡した．剖検所見は脳組織に大型異型細胞の増殖をみとめ，免疫染色ではEBER（EBV encoded small RNAs）陽性であり，加齢性EBV関連B細胞リンパ増殖性異常症による中枢神経浸潤と診断した．
A heating apparatus for hyperthermia therapy using 800 kHz focused ultrasound was developed in order to heat the well defined deep region. The generated from four spherical bowl transducers, center axes of which are crossed at one point. patterns were measured phantom and rabbit muscle vivo . Computer programs also with ultrasonic fields medium attenuation could be calculated. parameter dependences intensity distribution studied.
To evaluate the utility of repetitive nerve stimulation test (RNS) for differentiating multifocal motor neuropathy (MMN) and progressive muscular atrophy (PMA).We retrospectively enrolled 20 patients with MMN or PMA. We extracted results initial 3-Hz RNS in ulnar accessory nerves compared percentage frequency abnormal decremental responses between both groups.RNS was performed 8 9 MMN, 10 Patients had a significantly lower decrement (0.6 ± 4.0% vs. 10.3 6.5% PMA, P < 0.01) response (0 6 =...