A5021737256- Cerebrovascular and Carotid Artery Diseases
- Acute Ischemic Stroke Management
- Cardiovascular Health and Disease Prevention
- Intracranial Aneurysms: Treatment and Complications
- Vasculitis and related conditions
- Blood Pressure and Hypertension Studies
- Cardiac Imaging and Diagnostics
- Neurological and metabolic disorders
- Lipoproteins and Cardiovascular Health
- Peripheral Artery Disease Management
- Oropharyngeal Anatomy and Pathologies
- Peripheral Nerve Disorders
- Cardiac tumors and thrombi
- Inflammatory Myopathies and Dermatomyositis
- Systemic Sclerosis and Related Diseases
- Peripheral Neuropathies and Disorders
- Spinal Fractures and Fixation Techniques
- Orthopedic Surgery and Rehabilitation
- Parkinson's Disease Mechanisms and Treatments
- Glycosylation and Glycoproteins Research
- Genetic Neurodegenerative Diseases
- Moyamoya disease diagnosis and treatment
- Fetal and Pediatric Neurological Disorders
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Parkinson's Disease and Spinal Disorders
Tokyo-Kita Medical Center
2015-2024
Kobe University
1999-2017
Kobe University Hospital
2003-2015
Yokohama Rosai Hospital
2006-2009
University of Tsukuba
1986-1997
University of Geneva
1986
Rabin Medical Center
1986
Cornell University
1972
Revisions 1. CQs and Systematic Review (SR)In the subsections on dyslipidemia in assessment of risk factors, absolute ASCVD, lipid management targets as well drug therapy diet improving lifestyle habits, we created performed an SR based MINDS method.For our SR, essentially chose literature published before end 2015. Calculation Absolute RiskFollowing 2012 version, has been using calculation described this set guidelines.The NIPPON DATA80, which was used to calculate result baseline surveys...
Amyotrophic lateral sclerosis (ALS) is a devastating, incurable neurodegenerative disease. A subset of ALS patients manifests with early-onset and complex clinical phenotypes. We aimed to elucidate the genetic basis these cases enhance our understanding disease etiology facilitate development targeted therapies.
Abstract We determined the associations of follow-up blood pressure (BP) after stroke as a time-dependent covariate with risk subsequent ischemic stroke, well those BP levels difference in impact long-term clopidogrel or aspirin monotherapy versus additional cilostazol medication on secondary prevention. In sub-analysis randomized controlled trial (CSPS.com), patients between 8 and 180 days onset were randomly assigned to receive alone, combination clopidogrel. The percent changes,...
We report a patient with constitutional ring chromosome 22, in whom multifocal meningiomas were confirmed at necropsy, and discuss the relationship between change tumourigenesis of this patient.
We investigated the relationships between total cerebrospinal fluid (CSF) protein in diabetic patients and clinical characteristics of diabetes mellitus. The subjects comprised 16 (median age = 60.5 years, range 47–71) who were studied retrospectively. Patients with diseases known to be associated increases CSF excluded as far possible. median albumin quotient group 52.5 mg/dl (range 41–84) 6.13 × 10<sup>–3</sup> 4.0 13.1 10<sup>–3</sup>), respectively. These results...
Platelet-derived microparticle (PDMP) levels were measured using an enzyme-linked immunosorbent assay (ELISA) to elucidate the role of platelet activation in patients with polymyositis or dermatomyositis (PM/DM). PDMP active PM/DM (median 13.3 U/ml, interquartile range 9.9-20.7 n = 16) and those undergoing treatment (12.1 7.4-16.7 12) significantly higher than controls (6.5 5.0-8.4 26, vs. active, P 0.0001; treatment, 0.004). In a paired sampling study, decreased after glucocorticoid (P...
Abstract A 67‐year‐old man was admitted with a 2‐year history of dropped head. Neurological examination revealed ptosis, dysarthria, neck weakness, hyporeflexia all limbs, and autonomic failure. Electrophysiologic study showed 400% increment response to high‐rate repetitive nerve stimulation. Serum anti‐P/Q‐voltage‐gated calcium channel antibody positive, confirming the diagnosis Lambert–Eaton myasthenic syndrome (LEMS). His symptoms electrophysiological abnormalities improved oral...
We describe a Japanese boy with ring chromosome 18 in whom abnormal myelination was observed on magnetic resonance imaging. Cytogenetic investigation revealed 46, XY, r(18) (p11.2 q21.33). T2-weighted imaging scan of the brain demonstrated high signal intensity consistent myelination. Microsatellite marker analysis DNA only one copy myelin basic protein gene, derived from mother. The present case indicates that hemizygous state for gene may be related to
症例は36歳女性である．全身性エリテマトーデスおよび抗リン脂質抗体陽性で通院中であった．入院3週間前に突然左手の脱力を自覚した．1日前に右眼の視野狭窄を自覚したが5分ほどで改善した．頭部MRI上，右大脳半球分水嶺領域に多発する急性期脳梗塞巣をみとめ入院した．MRAでは右内頸動脈終末部，右後大脳動脈，左中大脳動脈に多発狭窄をみとめた．アスピリン・ヘパリンナトリウムによる加療をおこない，症候の増悪をみとめず経過した．入院1週間後の頭部MRAでは血管狭窄はいずれも消失しており，reversible cerebral vasoconstriction syndrome（RCVS）による脳梗塞と診断した．
Objective Post-stroke cognitive impairment often afflicts stroke survivors and is a major obstacle both for physical rehabilitation. Stroke risk scores ["Congestive heart failure, Hypertension, Age ≥75 years, Diabetes mellitus, Stroke" (CHADS2) "CHADS2 + creatinine clearance <60 mL/min" (R2CHADS2)] are used to assess the future of cardioembolic in patients with atrial fibrillation (AF). However, congestive hypertension, aging, diabetes stroke, renal dysfunction also factors impairment....
We report a case of acute pancreatitis complicating Salmonella enteritis. A 43-yr-old woman who was admitted to our department because enteritis developed clinical with laboratory and radiographic signs on the fourth hospital day. She free from symptoms eighth day, but her elevated serum amylase lipase levels persisted for more than 2 mo. In this case, complication bacterial caused by enteritidis, it characterized onset few days after sustained elevation pancreatic enzyme levels.
This report describes the rare case of a 72-year-old woman with spinal cord infarction who presented persistent diaphragmatic paralysis. Her neurological examination showed tetraplegia, sensory loss to pain and thermal stimulations, paradoxical abdominal movement. Chest X-ray fluoroscopy revealed absent A cervical magnetic resonance image bilateral anterior lesions from level second fifth vertebrae. Diaphragmatic paralysis should be recognized as clinical sign infarction. Particular...
The ratio of the internal carotid artery (ICA) to common (CCA), especially "AcT ratio," which is a modified measurement method acceleration time, useful for diagnosing ICA-origin stenosis. However, previous studies were single-center studies. Therefore, this multicenter, retrospective, cross-sectional study aimed determine whether using AcT estimating stenosis rates.