A5068915791- Antimicrobial Resistance in Staphylococcus
- Salmonella and Campylobacter epidemiology
- Antibiotic Resistance in Bacteria
- Vibrio bacteria research studies
- Bacterial Identification and Susceptibility Testing
- Bacteriophages and microbial interactions
- Listeria monocytogenes in Food Safety
- Antibiotics Pharmacokinetics and Efficacy
- Enterobacteriaceae and Cronobacter Research
- Pharmaceutical and Antibiotic Environmental Impacts
- Plant and Fungal Interactions Research
- Escherichia coli research studies
- Mycobacterium research and diagnosis
- Insect symbiosis and bacterial influences
- Genomics and Phylogenetic Studies
- Toxoplasma gondii Research Studies
- Microbial infections and disease research
- Clostridium difficile and Clostridium perfringens research
- Vector-borne infectious diseases
- Infectious Diseases and Mycology
- Bacterial biofilms and quorum sensing
- Biochemical and Structural Characterization
Sciensano (Belgium)
2018-2024
UCLouvain
2015-2017
Veterinary and Agrochemical Research Centre
2011-2015
Trinity College Dublin
1927
Linezolid is a critically important antibiotic used to treat human infections caused by MRSA and VRE. While linezolid not licensed for food-producing animals, linezolid-resistant (LR) isolates have been reported in European countries, including Belgium.To: (i) assess LR occurrence staphylococci enterococci isolated from different Belgian animals 2019 through selective monitoring; (ii) investigate the genomes relatedness of these isolates.Faecal samples (n = 1325) nasal swab 148) were...
This study compares the genome of an ST131 CMY-2-producing Escherichia coli isolate from a Danish patient with other E. isolates both human and animal origin.In 2016, (ESBL20160056) was obtained bloodstream infection. The ESBL20160056 compared genomes six broiler meat imported to Denmark, 15 Enterobase (http://enterobase.warwick.ac.uk) two European collaborators. plasmid sequenced using MinION Mk1B (Oxford Nanopore Technologies).The clustered together 13 fimH22 in distinct clade. clade...
To characterize the genetic basis of azithromycin resistance in Escherichia coli and Salmonella collected within EU harmonized antimicrobial (AMR) surveillance programme 2014-18 Danish AMR 2016-19.
Fifty-nine monophasic Salmonella enterica serovar Typhimurium isolates, collected in Belgium during the period from 2008 to 2011, have been serotyped as 4,[5]:i:- and shown harbor an fljB coding sequence. The genetic differences between these strains phenotypically biphasic were analyzed through PCR DNA sequencing. Genetic alterations promoter region affecting expression of phase 2 flagellin observed 53 isolates. Other events invertible carrying For remaining 4 no molecular with a reference...
of sequence type (ST) 11 is a hyper-epidemic nosocomial clone, which spreading worldwide among humans and emerging in pets. This the first report, to best our knowledge, multidrug-resistant (MDR)
Most bacteria found in ticks are not pathogenic to humans but coexist as endosymbionts and may have effects on tick fitness pathogen transmission. In this study, we cultured isolated 78 from 954 Ixodes ricinus collected 7 sites of a Belgian peri-urban forest. species were non-pathogenic environmental microorganisms, the Firmicutes (69.23%), Actinobacteria (17.95%) Proteobacteria (3.84%) phyla. One bacterium isolate was particularly noteworthy, Cedecea davisae, rare opportunistic bacterium,...
Methicillin-resistant Staphylococcus aureus (MRSA) presenting spa type t899 is commonly associated with sequence 9 (ST9) but also increasingly linked to ST398. This study provides genomic insight into the diversity of isolates using core genome multilocus typing (cgMLST), single nucleotide polymorphism (SNP)-based phylogeny, and description selected antimicrobial resistance virulence markers. The SNP-based phylogenic tree showed that sharing same (t899) different STs highly diverged in their...
Livestock-associated methicillin-resistant Staphylococcus aureus (LA-MRSA) is an emerging MRSA lineage rapidly evolving in the community. In this report, we present draft genome sequences of nine LA-MRSA strains. These strains were isolated from meat and a human nasal swab sample belong to one unique spa type (t899), but three different sequence types, ST398, ST9, ST4034.
The aim of this study was to develop a highly multiplexed bead array detect genes and/or mutations frequently associated with resistance antimicrobials the β-lactam, (fluoro)quinolone, colistin, macrolide and aminoglycoside families in Enterobacteriaceae such as Escherichia coli, Shigella spp. Salmonella Ligase Chain Reaction Luminex® technology were combined 53-plex assay designed target selected genetic markers 3 internal controls. AMR-ARRAY consistently detected determinants compared...
Identifying antimicrobial resistance (AMR) genes and determining their occurrence in Gram-positive bacteria provide useful data to understand how can be acquired maintained these bacteria. We describe an in-house bead array targeting AMR of allowing rapid detection all at once a reduced cost. A total 41 probes were designed target frequently associated with tetracycline, macrolides, lincosamides, streptogramins, pleuromutilins, phenicols, glycopeptides, aminoglycosides, diaminopyrimidines,...
Linezolid is a critically important antimicrobial used in human medicine. While linezolid not licensed for food-producing animals, the veterinary use of other antimicrobials, such as phenicols (e.g., florfenicol), could cross/co-select linezolid-resistant (LR) bacteria. Such LR strains pose great concern public health due to their potential transfer between animals and humans. This study explored possible associations epidemiological risk factors, including phenicol use, occurrence bacteria,...