- Meningioma and schwannoma management
- Neurofibromatosis and Schwannoma Cases
- Spinal Fractures and Fixation Techniques
- Glioma Diagnosis and Treatment
- Traumatic Brain Injury and Neurovascular Disturbances
- Pituitary Gland Disorders and Treatments
- COVID-19 and healthcare impacts
- Vascular Malformations Diagnosis and Treatment
- Brain Metastases and Treatment
- Delphi Technique in Research
- Cardiac, Anesthesia and Surgical Outcomes
- Lung Cancer Treatments and Mutations
- Lung Cancer Research Studies
- Health Systems, Economic Evaluations, Quality of Life
- Intracerebral and Subarachnoid Hemorrhage Research
- Neurosurgical Procedures and Complications
- Fetal and Pediatric Neurological Disorders
- Hip and Femur Fractures
- Intracranial Aneurysms: Treatment and Complications
- Spine and Intervertebral Disc Pathology
- Head and Neck Surgical Oncology
- Cerebrospinal fluid and hydrocephalus
- Facial Nerve Paralysis Treatment and Research
- Meta-analysis and systematic reviews
- Congenital Anomalies and Fetal Surgery
Walton Centre
2021-2025
University of Liverpool
2021-2025
University College London
2024-2025
National Hospital for Neurology and Neurosurgery
2025
University College London Hospitals NHS Foundation Trust
2024
Salford Royal Hospital
2023
Liverpool College
2023
Rashtrasant Tukadoji Maharaj Nagpur University
2023
Imperial College London
2022
Sheffield Teaching Hospitals NHS Foundation Trust
2022
Cranioplasty is an operation that aims to repair a defect in the skull. Indications commonly include Traumatic Brain Injury (TBI), tumours, and infections. It carries high rate of postoperative morbidity. Due underlying pathology nature patients' Health-related Quality life (QoL) can be severely affected. Patient reported outcomes (PROs) are poorly understood following cranioplasty. To investigate PROs cranioplasty cross-sectional cohort study adults undergoing between 01/03/2010-30/08/2020...
Intracranial meningioma with bone involvement and primary intraosseous is uncommon. There currently no consensus for optimal management. This study aimed to describe the management strategy outcomes a 10-year illustrative cohort, propose an algorithm aid clinicians in selecting cranioplasty material such patients.A single-centre, retrospective cohort (January 2010-August 2021). All adult patients requiring cranial reconstruction due or were included. Baseline patient characteristics,...
The outcomes following re-operation for meningioma are poorly described. aim of this study was to identify risk factors a performance status outcome second operation recurrent meningioma. A retrospective, comparative cohort conducted. primary measure World Health Organization performance. Secondary were complications, and overall progression free survival (OS PFS respectively). Baseline clinical characteristics, tumor details, details collected. Multivariable binary logistic regression used...
Cranioplasty remains an essential procedure following craniectomy but is associated with high morbidity. We investigated factors outcomes first alloplastic cranioplasty.A single-centre, retrospective cohort study of patients undergoing cranioplasty at a tertiary neuroscience centre (01 March 2010-01 September 2021). Patient demographics and craniectomy/cranioplasty details were extracted. Primary outcome was all-cause explantation. Secondary explantation secondary to infection, surgical...
Few studies have evaluated meningioma patients' longer-term health-related quality of life (HRQoL) following diagnosis and treatment, particularly in those with incidental, actively monitored tumours.A single-center, cross-sectional study was completed. Adult patients surgically managed or more than five years follow-up were included. The patient-reported outcome measures RAND SF-36, EORTC QLQ-C30 QLQ-BN20 used to evaluate HRQoL. HRQoL scores compared normative population data. Outcome...
BACKGROUND: After meningioma surgery, approximately 1 in 3 patients will have residual tumor that requires ongoing imaging surveillance. The precise volumetric growth rates of these tumors are unknown. OBJECTIVE: To identify the meningioma, trajectory, and factors associated with progression. METHODS: Patients identified at a tertiary neurosurgery center between 2004 2020 were retrospectively reviewed. Tumor volume was measured using manual segmentation, after surgery every follow-up MRI...
Tectal plate gliomas (TPGs) are a heterogeneous group of uncommon brain tumors. TPGs considered indolent and usually managed conservatively but they have the potential to transform into higher-grade The aims this study were investigate natural history adult TPG, treatment outcomes, overall survival. A retrospective cohort analysis was performed patients with TPG between 1993 2021. Baseline clinical, radiologic, management characteristics collected. primary outcome tumor progression, defined...
It is of vital importance to comprehensively and transparently report clinical trial activity. The SPIRIT 2013 CONSORT 2010 statements exist define items be reported in protocols randomized controlled trials, respectively. aim this methodological review was assess the reporting quality pediatric neuro-oncology result articles.
Healthcare students have played a significant role in the National Health Service during COVID-19 pandemic. We captured data on well-being of medical acute phase pandemic with Social and Psychological Impact students: national survey Evaluation (SPICE-19) study. will evaluate changes mental health nursing 1 year after SPICE-19, cross-sectional study, to understand impact pandemic, inform policies. This study be national, multi-institution, cross-discipline An online 53-item demographics,...
Abstract Cerebral cavernous malformations (CCMs) are commonly diagnosed, with a low reported rate of haemorrhage on long-term follow-up. The identification factors predictive future risk would assist in guiding the management patients CCM. aim this study was to identify variables associated haemorrhage, and calculate We conducted retrospective diagnosed CCM, managed at specialist tertiary neuroscience centre (2007–2019). primary outcome symptomatic secondary outcomes were increased using...
Abstract Long-standing overt ventriculomegaly in adults (LOVA) is a heterogenous group of conditions with differing presentations. Few studies have evaluated success rates available surgical treatments, or ascertained the natural history. There need to assess efficacy both endoscopic third ventriculostomy (ETV) and ventriculoperitoneal shunt (VPS) as first-line treatments. We conducted retrospective, single-centre study LOVA at tertiary neurosurgery centre England, UK, aiming identify...
To explore our experience of hosting the 10th Annual Neurology and Neurosurgery Interest Group-Society British Neurological Surgeons (NANSIG-SBNS) Careers Day, held virtually for first time. Reflective feedback review an international, virtual neurosurgery careers day. The authors reflect on logistics organizing event, pre- post-event provided by delegates. Recommendations have been made how to successfully host a event. key themes that permeated event outlined discussed in context received....
Abstract Background Comprehensive and transparent reporting of clinical trial activity is important. The Standard Protocol Items: Recommendations for Interventional Trials (SPIRIT) 2013 Consolidated Standards Reporting (CONSORT) 2010 statements define the items to be reported in protocols randomized controlled trials, respectively. aim this methodological review was assess quality adult neuro-oncology result articles. Methods Adult primary secondary brain tumor phase 3 articles published...