A5015509880- Cervical and Thoracic Myelopathy
- Spine and Intervertebral Disc Pathology
- Spinal Fractures and Fixation Techniques
- Neurosurgical Procedures and Complications
- Intracerebral and Subarachnoid Hemorrhage Research
- Delphi Technique in Research
- Spinal Hematomas and Complications
- Cerebrospinal fluid and hydrocephalus
- Glioma Diagnosis and Treatment
- Spinal Dysraphism and Malformations
- Fetal and Pediatric Neurological Disorders
- RNA and protein synthesis mechanisms
- Circadian rhythm and melatonin
- Modular Robots and Swarm Intelligence
- Spinal Cord Injury Research
- Aortic aneurysm repair treatments
- Head and Neck Surgical Oncology
- Traumatic Brain Injury and Neurovascular Disturbances
- Innovations in Medical Education
- Case Reports on Hematomas
- History of Medical Practice
- Sleep and related disorders
- Micro and Nano Robotics
- Advanced MRI Techniques and Applications
- Advanced Materials and Mechanics
University of Manchester
2021-2024
University of Cambridge
2023-2024
New York University Abu Dhabi
2018-2024
New York University
2019
Narrative Review.To (i) discuss why assessment and monitoring of disease progression is critical in Degenerative cervical myelopathy (DCM); (ii) outline the important features an ideal tool (iii) current novel strategies for detecting subtle deterioration DCM.Literature review.Degenerative overarching term used to describe progressive injury spinal cord by age-related changes axis. Based on a study Smith et al (2020), prevalence DCM approximately 2.3% expected rise as global population ages....
Stress and sleep are tightly regulated as a result of the substantial overlap in neurotransmitter signaling regulatory pathways between neural centers that modulate mood sleep-wake cycle. The chronicity stressor variability coping with it major determinants psychiatric outcomes subsequent effect on sleep. regulation is mediated by interaction homeostatic circadian process according to two-process model. Chronic stress induces stress-related disorders which associated deficient homeostasis....
Developing new clinical measures for degenerative cervical myelopathy (DCM) is an AO Spine RECODE-DCM Research, international and multi-stakeholder partnership, priority. Difficulties in detecting DCM its changes cause diagnostic treatment delays settings heightened costs trials due to elevated recruitment targets. Digital outcome can tackle these challenges their ability measure disease remotely, repeatedly, more economically.
Background Degenerative cervical myelopathy (DCM) is a progressive chronic spinal cord injury estimated to affect 1 in 50 adults. Without standardised guidance, clinical research studies have selected outcomes at their discretion, often underrepresenting the disease and limiting comparability between studies. Utilising standard minimum data set formed via multi-stakeholder consensus can address these issues. This combines processes define core outcome (COS)—a list of key outcomes—and...
Progress in degenerative cervical myelopathy (DCM) is hindered by inconsistent measurement and reporting. This impedes data aggregation outcome comparison across studies. limitation can be reversed developing a core set (CMS) for DCM research. Previously, the AO Spine Research Objectives Common Data Elements (AO RECODE-DCM) defined 'what' should measured DCM: next step of this initiative to determine 'how' measure these features. protocol outlines steps necessary development CMS research...
ABSTRACT Objectives To assess the validity of MoveMed, a battery performance outcome measures performed using mobile phone application, in measurement degenerative cervical myelopathy (DCM). Design Prospective observational study. Setting Decentralised secondary care England, United Kingdom. Participants 27 adults aged 60 (SD: 11) who live with DCM and possess an approved smartphone. Primary Criteria from Consensus-based Standards for selection health Measurement Instruments (COSMIN) manual...
<sec> <title>BACKGROUND</title> Developing new clinical measures for degenerative cervical myelopathy (DCM) is an AO Spine RECODE-DCM Research, international and multi-stakeholder partnership, priority. Difficulties in detecting DCM its changes cause diagnostic treatment delays settings heightened costs trials due to elevated recruitment targets. Digital outcome can tackle these challenges their ability measure disease remotely, repeatedly, more economically. </sec> <title>OBJECTIVE</title>...
A chronic subdural haematoma (cSDH) is an encapsulated collection of fluid and blood degradation products in the space. It increasingly common, affecting older people those living with frailty. Currently, no guidance exists to define optimal care from onset symptoms through recovery. This paper presents first consensus-built recommendations for best practice cSDH, co-designed support each stage patient pathway. Guideline development was led by a multidisciplinary Steering Committee...
Abstract Certain awns utilize actuating mechanisms that harness energy from variations in aerial humidity to self‐burrow their seeds into the soil. Here morphokinematics of such hygroresponse awn feather grass Stipa epilosa is described. The elongated body typically doubly bent, and has three segments with different functionalities: long stiff proximal segment twists reversibly generate thrust for burrowing seed, plumose flexible distal contributes dispersion, short middle provides a bent...
To explore our experience of hosting the 10th Annual Neurology and Neurosurgery Interest Group-Society British Neurological Surgeons (NANSIG-SBNS) Careers Day, held virtually for first time. Reflective feedback review an international, virtual neurosurgery careers day. The authors reflect on logistics organizing event, pre- post-event provided by delegates. Recommendations have been made how to successfully host a event. key themes that permeated event outlined discussed in context received....
ABSTRACT Objectives To assess the reliability of MoveMed battery performance outcome measures. Design Prospective observational study. Setting Decentralised secondary care in England, United Kingdom. Participants Seven adults aged 59.5 (SD 12.4) who live with degenerative cervical myelopathy (DCM) and possess an approved smartphone. Primary measures The primary was to determine test-retest outcomes using intra-class correlation agreement (ICC ). measurement error both standard mean (SEM )...
Background Developing new clinical measures for degenerative cervical myelopathy (DCM) is an AO Spine RECODE-DCM research priority. Difficulties detecting DCM, and changes in cause diagnostic treatment delays settings heightened costs trials due to elevated recruitment targets. Digital outcome can tackle these challenges their ability measure disease remotely, repeatedly, more economically. Objective The study aims assess the validity of MoveMed, a battery performance performed using...
Degenerative cervical myelopathy (DCM), a progressive spinal cord injury caused by compression from degenerative pathology, often presents with neck pain, sensorimotor dysfunction in the upper or lower limbs, gait disturbance, and bladder bowel dysfunction. Its symptomatology is very heterogeneous, making early detection as well measurement understanding of underlying factors their consequences challenging. Increasingly, evidence suggests that DCM may consist subgroups disease, which are yet...
DNA encodes all sorts of information that makes us human, but, aside from encoding genes, could also encode for a mapping musical rhythms in very abstract way? This project sought to generate out and compose piece gene's rhythmic sequence. Computational rules inspired by geometric analyses guided the DNA's molecular structure into timelines melodic scales; these basic structures were then used song according sickle cell gene The generated this ‘genetic analysis’ alternate pleasantly between...
ABSTRACT Introduction Progress in degenerative cervical myelopathy (DCM) is hindered by inconsistent measurement and reporting of outcomes. This can, for example, impede the aggregation data comparison outcomes between studies. limitation can be reversed developing a core set (CMS) use DCM research. Previously, AO Spine Research Objectives Common Data Elements (AO RECODE-DCM) defined ‘what’ should measured DCM: specifically, elements outcome disease. The next step this initiative to...
<sec> <title>BACKGROUND</title> Developing new clinical measures for degenerative cervical myelopathy (DCM) is an AO Spine RECODE-DCM research priority. Difficulties detecting DCM, and changes in cause diagnostic treatment delays settings heightened costs trials due to elevated recruitment targets. Digital outcome can tackle these challenges their ability measure disease remotely, repeatedly, more economically. </sec> <title>OBJECTIVE</title> The study aims assess the validity of MoveMed, a...