Ellie Edlmann
A5062751010- Neurosurgical Procedures and Complications
- Intracerebral and Subarachnoid Hemorrhage Research
- Traumatic Brain Injury and Neurovascular Disturbances
- Spinal Fractures and Fixation Techniques
- Spinal Hematomas and Complications
- Glioma Diagnosis and Treatment
- Head and Neck Surgical Oncology
- Cardiac, Anesthesia and Surgical Outcomes
- Spine and Intervertebral Disc Pathology
- Clinical practice guidelines implementation
- Surgical Simulation and Training
- Diversity and Career in Medicine
- Hip and Femur Fractures
- Venous Thromboembolism Diagnosis and Management
- Intracranial Aneurysms: Treatment and Complications
- Colorectal Cancer Surgical Treatments
- Atrial Fibrillation Management and Outcomes
- Pituitary Gland Disorders and Treatments
- Brain Metastases and Treatment
- Musculoskeletal pain and rehabilitation
- Aortic Disease and Treatment Approaches
- Health and Medical Research Impacts
- Lung Cancer Research Studies
- Adrenal and Paraganglionic Tumors
- Growth Hormone and Insulin-like Growth Factors
University Hospitals Plymouth NHS Trust
2021-2024
University of Plymouth
2020-2024
University of Cambridge
2015-2024
Addenbrooke's Hospital
2015-2024
Derriford Hospital
2015-2024
Great Ormond Street Hospital
2022
University College London
2022
University of Bristol
2022
St George's, University of London
2022
Oxford University Press (United Kingdom)
2020
Chronic subdural hematoma is a common neurologic disorder that especially prevalent among older people. The effect of dexamethasone on outcomes in patients with chronic has not been well studied.
Cauda equina syndrome (CES) results from nerve root compression in the lumbosacral spine, usually due to a prolapsed intervertebral disc. Evidence for management of CES is limited by its infrequent occurrence and lack standardised clinical definitions outcome measures. This prospective multi-centre observational cohort study adults with UK. We assessed presentation, investigation, management, all Core Outcome Set domains up one year post-operatively using clinician participant reporting....
Chronic subdural haematoma (CSDH) is a common neurosurgical condition, typically treated with surgical drainage of the haematoma. However, surgery associated mortality and morbidity, including up to 20% recurrence CSDH. Steroids, such as dexamethasone, have been identified potential therapy for reducing risk in surgically CSDHs. They also used conservative treatment option, thereby avoiding altogether. The hypothesis Dex-CSDH trial that two-week course dexamethasone symptomatic patients CSDH...
Chronic subdural hematoma (CSDH) is a common neurosurgical pathology, yet conflicting opinions exist concerning the pathophysiological processes involved. Many consider CSDH product of an aged acute (ASDH) secondary to trauma. Serial imaging, however, has demonstrated formation in patients without any initial ASDH. To understand relevance hemorrhage cohort with CSDH, transformation from ASDH were categorized as CSDH-acute transformed (CSDH-AT) and those at outset CSDH-de-novo (CSDH-DN). A 41...
Background Chronic subdural haematoma is a collection of ‘old blood’ and its breakdown products in the space predominantly affects older people. Surgical evacuation remains mainstay management symptomatic cases. Objective The Dex-CSDH (DEXamethasone SubDural Haematoma) randomised trial investigated clinical effectiveness cost-effectiveness dexamethasone patients with chronic haematoma. Design This was parallel, superiority, multicentre, pragmatic, controlled trial. Assigned treatment...
There are many questions that remain unanswered regarding outcomes following cranioplasty including the timing of craniectomy as well material used.To establish and evaluate 30-d for all cranial reconstruction procedures in United Kingdom (UK) Ireland through a prospective multicenter cohort study.Patients undergoing insertion or revision between June 1, 2019 November 30, 25 neurosurgical units were included. Data collected include demographics, date indication, date, outcome.In total, 313...
Purpose: Cauda equina syndrome (CES) is a spinal emergency with clinical symptoms and signs that have low diagnostic accuracy. National guidelines in the United Kingdom (UK) state all patients should undergo an MRI prior to referral specialist units surgery be performed at earliest opportunity. We aimed evaluate current practice of investigating treating suspected CES UK.Materials Methods: A retrospective, multicentre observational study investigation management was conducted across UK,...
A common neurosurgical condition, chronic subdural haematoma (cSDH) typically affects older people with other underlying health conditions. The care of this potentially vulnerable cohort is often, however, fragmented and suboptimal. In complex conditions, multidisciplinary guidelines have transformed patient experience outcomes, but no such framework exists for cSDH. This paper outlines a protocol to develop the first comprehensive guideline from diagnosis long-term recovery
Introduction Fractures of the odontoid process frequently result from low impact falls in frail or older adults. These are increasing incidence and importance as population ages. In UK, fractures adults usually managed hard collars to immobilise fracture promote bony healing. However, healing does not always occur adults, is associated with quality life, functional, pain outcomes. Further, can cause complications such skin pressure ulcers, swallowing difficulties personal care. We...
Abstract The Dex-CSDH trial is a randomised, double-blind, placebo-controlled of dexamethasone for patients with symptomatic chronic subdural haematoma. commenced an internal pilot, whose primary objective was to assess the feasibility multi-centre recruitment. Primary outcome data collection and safety were also assessed, whilst maintaining blinding. We aimed recruit 100 from United Kingdom Neurosurgical Units within 12 months. Trial participants randomised 2-week course or placebo in...
Core Outcome Sets (COSs) are necessary to standardize reporting in research studies. This is urgently required the field of chronic subdural hematoma (CSDH), one most common disease entities managed neurosurgery and topic several recent trials. To complement development a COS, standardized definition baseline Data Elements (DEs) be collected CSDH patients, would further improve study quality comparability this heterogeneous population.To, first, define COS for all future studies; and,...
A chronic subdural haematoma (cSDH) is an encapsulated collection of fluid and blood degradation products in the space. It increasingly common, affecting older people those living with frailty. Currently, no guidance exists to define optimal care from onset symptoms through recovery. This paper presents first consensus-built recommendations for best practice cSDH, co-designed support each stage patient pathway. Guideline development was led by a multidisciplinary Steering Committee...
Chronic subdural hematoma (CSDH) is a collection of blood and fluid that arises on the brain surface due to combination trauma and/or inflammation. The mainstay treatment surgical drainage, but CSDH can recur. Dexamethasone has been shown reduce recurrence, its mechanism action not fully elucidated. Understanding inflammatory mediators driving formation recurrence how dexamethasone alters this help develop new therapeutic strategies.A subgroup adult patients recruited Dex-CSDH trial,...
OBJECTIVE Within neurosurgery, there are fewer women than men at all levels. The authors aimed to assess whether opportunities and representation within neurosurgery proportional the existing gender gap. METHODS analyzed program of 2019 joint European Association Neurosurgical Societies (EANS)/Society British Neurological Surgeons (SBNS) conference proportions presentations given through abstract submission invitation by women. They compared previous in 2007 board-certified neurosurgeons....