- Intracranial Aneurysms: Treatment and Complications
- Traumatic Brain Injury and Neurovascular Disturbances
- Spine and Intervertebral Disc Pathology
- Glioma Diagnosis and Treatment
- Meningioma and schwannoma management
- Cerebrovascular and Carotid Artery Diseases
- Spinal Fractures and Fixation Techniques
- Epilepsy research and treatment
- Bone Tumor Diagnosis and Treatments
- Orthopedic Infections and Treatments
- Facial Trauma and Fracture Management
- Medical and Biological Sciences
- Emergency and Acute Care Studies
- Vascular Malformations Diagnosis and Treatment
- Advanced Neuroimaging Techniques and Applications
- Neurosurgical Procedures and Complications
- Neurological Complications and Syndromes
- Medical Imaging and Analysis
- Retinal Imaging and Analysis
- Patient Satisfaction in Healthcare
- Infectious Diseases and Tuberculosis
- Fetal and Pediatric Neurological Disorders
- Innovations in Medical Education
- Musculoskeletal pain and rehabilitation
- Cerebrospinal fluid and hydrocephalus
Leeds Teaching Hospitals NHS Trust
2019-2024
Leeds General Infirmary
2018-2023
University of Leeds
2023
Addenbrooke's Hospital
2017-2021
University of Cambridge
2017-2021
North Bristol NHS Trust
2014-2020
Southmead Hospital
2015
OBJECTIVE The aim of this study was to provide a comprehensive benchmark 30-day ventriculoperitoneal (VP) shunt failure rates for single institution over 5-year period both adult and pediatric patients, compare with the results in previously published literature, establish factors associated failure. METHODS A retrospective database search undertaken identify all VP operations performed single, regional neurosurgical unit during period. Data were collected regarding patient age, sex, origin...
Background and purpose Wide-necked bifurcation aneurysms pose a significant challenge to the treating clinician. The Contour Neurovascular System embolization device is novel tool for treatment of such intracranial aneurysms. We report on our experience with this device. Methods Prospective clinical radiological data were collected all patients treated at center. All an elective basis. Results have 11 successfully date. women mean (SD) age 65.0 (6.4) years. In total, four basilar tip, two...
There are many questions that remain unanswered regarding outcomes following cranioplasty including the timing of craniectomy as well material used.To establish and evaluate 30-d for all cranial reconstruction procedures in United Kingdom (UK) Ireland through a prospective multicenter cohort study.Patients undergoing insertion or revision between June 1, 2019 November 30, 25 neurosurgical units were included. Data collected include demographics, date indication, date, outcome.In total, 313...
Recent evidence has suggested that an admission neutrophil-to-lymphocyte ratio (NLR) of ≥ 5.9 predicts delayed cerebral ischemia (DCI) in aneurysmal subarachnoid hemorrhage (aSAH). The primary aims this study were to assess reproducibility and ascertain the predictive ability NLR on subsequent days postictus. Secondary included identification additional inflammatory markers.A single-center, retrospective all patients aged 18 years with aSAH between May 2014 July 2018 was performed. Patient...
Abstract Patient handover is paramount for effective patient care and often poorly documented or incomplete. North Bristol NHS Trust weekend proformas identify medical patients requiring review. Many seen during on-call shifts are not handed over. Our aim was to develop Friday ward round proforma sheets patients, encourage clear documentation of management plans in order improve important information, particularly ceiling decisions. Questionnaires were completed by F1 doctors regarding...
<h3>ABSTRACT</h3> <h3>BACKGROUND AND PURPOSE:</h3> The contour neurovascular embolization device is a novel way to treat wide-necked bifurcation aneurysms (WNBA), which often pose significant treatment challenges. In this study, we aim evaluate the efficacy and safety profile of device. <h3>MATERIALS METHODS:</h3> Prospective clinical radiological data was collected for all patients treated with Contour at our centre, between January 2017 December 2018. All were electively, unruptured....
Introduction: Papilloedema is an important clinical sign in the assessment of neurosurgical patients presenting with suspected shunt malfunction.Methods: We describe our 18-month experience using a newly acquired nonmydriatic digital retinal camera to acquire fundal photographs for this purpose.Results: It was used take 67 malfunction and 54% these images were discussed on-call ophthalmology team advice. Of 81% had instant input provided by remainder sent department formal assessment. all...
Although resection of mesial temporal lobe lesions can be achieved with relatively low morbidity, resective surgery is not without risk. Whilst many found in the anterior mesiotemporal are low-grade entities, transforming and high-grade have also been demonstrated. We investigate feasibility utilising serial quantitative volumetric imaging, to determine if a strategy imaging surveillance safely employed for management radiologically diagnosed tumours confirmed histological diagnosis.A...
Abstract Glioblastoma (GB) is the most aggressive primary brain tumour in adults associated with survival rates below 5% despite treatment. Tumour repopulating residual cells surgical cavity resist treatment due to their molecular heterogeneity. Single-cell transcriptomic studies have linked GB heterogeneity cell cycle; however, it remains unclear what extent cycle states affect infiltrative capacity of GB. The “go or grow” paradigm predicts that migration and proliferation are separate...
Osteochondromas are one of the commonest benign bone tumours, but rarely found in spine. Cord compression due to these lesions is even rarer. We describe a case C2 lamina osteochondroma causing cord 20 year old patient who presented with progressive myelopathy. report on technical aspects operation which resulted good decompression and complete excision. Post-operatively made an uncomplicated recovery. recommend spinal monitoring as routine for such procedures. However, whether or not fusion...