A5006553634- Glioma Diagnosis and Treatment
- Radiomics and Machine Learning in Medical Imaging
- Meningioma and schwannoma management
- Cardiac, Anesthesia and Surgical Outcomes
- HIV/AIDS Research and Interventions
- Abdominal Surgery and Complications
- Cerebrospinal fluid and hydrocephalus
- Head and Neck Surgical Oncology
- HIV-related health complications and treatments
- Enhanced Recovery After Surgery
- Traumatic Brain Injury and Neurovascular Disturbances
- Brain Metastases and Treatment
- Neonatal Respiratory Health Research
- Neurofibromatosis and Schwannoma Cases
- Spinal Fractures and Fixation Techniques
- Gestational Diabetes Research and Management
- Anesthesia and Pain Management
- Adrenal and Paraganglionic Tumors
- Spinal Dysraphism and Malformations
- Pregnancy and Medication Impact
- Neurosurgical Procedures and Complications
- Acute Kidney Injury Research
- Neonatal and fetal brain pathology
- Pituitary Gland Disorders and Treatments
Oxford University Hospitals NHS Trust
2021-2024
University of Oxford
2019-2023
John Radcliffe Hospital
2020-2023
Eton College
2019
There are many questions that remain unanswered regarding outcomes following cranioplasty including the timing of craniectomy as well material used.To establish and evaluate 30-d for all cranial reconstruction procedures in United Kingdom (UK) Ireland through a prospective multicenter cohort study.Patients undergoing insertion or revision between June 1, 2019 November 30, 25 neurosurgical units were included. Data collected include demographics, date indication, date, outcome.In total, 313...
Abstract Purpose The role of repeat resection for recurrent glioblastoma (rGB) remains equivocal. This study aims to assess the overall survival and complications rates single or rGB. Methods A single-centre retrospective review all patients with IDH-wildtype managed surgically, between January 2014 2022, was carried out. Patient factors influencing prognosis were analysed, using Kaplan–Meier Cox regression methods. Results Four hundred thirty-two included, whom 329 underwent resection, 83...
Abstract Background Elderly patients with glioblastoma are perceived to face a poor prognosis perceptions surrounding older age and relative lack of randomized data contributing. This study evaluated survival prognosticators in elderly more accurately guide their treatment. Methods The records 169 (≥70 years) new diagnosis who had undergone neurosurgical intervention were retrospectively examined for patient sex, age, performance status, comorbidities, MGMT promoter methylation, surgical...
Cognitive impairment following anti-tumor treatment is a common concern for brain tumor patients. However, growing evidence indicates that significant impairments can be present even before treatment. The purpose of this study was to identify factors explain variability in pretreatment test performance, beyond burden. Using multi-step linear regression, we retrospectively probed the contribution clinical-, tumor-, patient-, and self-reported variance performance among 96 treatment-naïve...
Abstract Purpose The role of repeat resection for recurrent glioblastoma (rGBM) remains equivocal. This study aims to assess the overall survival and complications rates single or rGBM. Methods A centre retrospective review all patients with IDH-wildtype managed surgically, between January 2014 2022, was carried out. Patient factors influencing prognosis were analysed, using Kaplan–Meier Cox regression methods. Results 432 included, whom 329 underwent resection, 83 had two resections 20...
Abstract AIMS Elderly patients with glioblastoma are perceived to face a poor prognosis perceptions surrounding older age and relative lack of randomized data contributing. This study aimed evaluate survival prognosticators in elderly more accurately guide their treatment. METHOD The records 169 (≥70 years) new diagnosis who had undergone neurosurgical intervention were retrospectively examined for patient sex, age, performance status, comorbidities, MGMT promoter methylation, surgical...
Abstract BACKGROUND Elderly patients with glioblastoma are perceived to face a poor prognosis, perceptions around older age and relative lack of randomized data raising concern about their undertreatment. The EANO guidelines recommend >70-year-old good performance status undergo maximal safe resection followed by hypofractionated (40 Gy in 15 fractions, i.e. RT40/15) radiotherapy or without concurrent adjuvant Temozolomide (TMZ), depending on MGMT promoter methylation. This study...