- Glioma Diagnosis and Treatment
- Meningioma and schwannoma management
- Neurosurgical Procedures and Complications
- Spinal Fractures and Fixation Techniques
- Head and Neck Surgical Oncology
- Spine and Intervertebral Disc Pathology
- Transcranial Magnetic Stimulation Studies
- Traumatic Brain Injury and Neurovascular Disturbances
- Intraoperative Neuromonitoring and Anesthetic Effects
- Advanced Neuroimaging Techniques and Applications
- Cerebrospinal fluid and hydrocephalus
- Vascular Malformations Diagnosis and Treatment
- Radiomics and Machine Learning in Medical Imaging
- Management of metastatic bone disease
- Pituitary Gland Disorders and Treatments
- Intracerebral and Subarachnoid Hemorrhage Research
- Brain Metastases and Treatment
- Stroke Rehabilitation and Recovery
- Neurofibromatosis and Schwannoma Cases
- Spinal Dysraphism and Malformations
- Bone Tumor Diagnosis and Treatments
- Pelvic and Acetabular Injuries
- Intracranial Aneurysms: Treatment and Complications
- Oral and Maxillofacial Pathology
- Telemedicine and Telehealth Implementation
King's College Hospital NHS Foundation Trust
2018-2024
King's College London
2017-2024
King's College Hospital
2017-2024
Neurological Surgery
2024
Tribhuvan University Teaching Hospital
2024
Dhulikhel Hospital
2023
The King's College
2022
Wellcome Centre for Human Neuroimaging
2022
Addenbrooke's Hospital
2021
University of Cambridge
2021
Penfield's motor homunculus describes a caricaturised yet useful representation of the map various body parts on pre-central cortex. We propose supplemental clinically represented areas human in cortex and novel subcortical corticospinal tract map. believe this knowledge is essential for safe surgery patients with eloquent brain lesions. A single-institution retrospective cohort study who underwent craniotomy lesions intraoperative neuromonitoring (cortical subcortical) between 2015 2020 was...
There are many questions that remain unanswered regarding outcomes following cranioplasty including the timing of craniectomy as well material used.To establish and evaluate 30-d for all cranial reconstruction procedures in United Kingdom (UK) Ireland through a prospective multicenter cohort study.Patients undergoing insertion or revision between June 1, 2019 November 30, 25 neurosurgical units were included. Data collected include demographics, date indication, date, outcome.In total, 313...
Abstract Background Lesions within the primary motor cortex (M1) and corticospinal tract (CST) represent a significant surgical challenge with delicate functional trade-off that should be integrated in overall patient-centered treatment plan. Methods Patients lesions M1 CST preoperative cortical subcortical mapping (navigated transcranial magnetic stimulation [nTMS] tractography), intraoperative mapping, provisional histologic information (smear without 5-aminolevulinic acid [5-ALA]) were...
Background: This study has compared the difference in serum bilirubin between patients with gangrenous and non-gangrenous appendicitis. Methods: A prospective analytical of, 141 who underwent appendectomy, from March 2010 to 2011 Manipal Teaching Hospital, Pokhara, Nepal was carried out. Clinico-demographic data, Alvarado’s score, total bilirubin, leucocyte count histopathological report of all cases were collected a prestructured proforma. Comparison appendicitis groups out using...
Brain tumour surgery in visual eloquent areas poses significant challenges to neurosurgeons and has reported inconsistent results. This is a single-centre prospective cohort study of patients admitted for asleep intra-axial lesions areas. Demographic clinical information, data from tractography evoked potentials (VEPs) monitoring were recorded correlated with outcomes. Thirty-nine included (20 females, 19 males; mean age 52.51 ± 14.08 years). Diffuse intrinsic glioma was noted 61.54%...
Abstract Background Repetitive transcranial magnetic stimulation (rTMS) is established for depression and rehabilitation after stroke emerging cognitive rehabilitation. We sought to evaluate patient carer perceptions toward rTMS neurosurgery. Methods Two surveys were undertaken. Group 1: Patients who received 7 days of motor or language severe postoperative deficits following lesional resection prospectively surveyed on the last day their treatment, as well next kin. 2: had previously been...
Introduction: Questionnaire based assessment is a simple, scientific tool to collect responses from individuals and standardised questionnaires can be used assess health care quality of institution. The aim this study was service private hospital on the basis questionnaire-based data collected patients admitted in using (SERVQUAL) questionnaire method.
 Methods: A descriptive cross sectional conducted 203 adult Fishtail Hospital Research Centre, Pokhara, Nepal January 2015 2016....
Background: The role played by the non-dominant parietal lobe in motor cognition, attention and spatial awareness networks has potentiated use of awake surgery. When this is not feasible, asleep monitoring mapping techniques should be used to achieve an onco-functional balance. Objective: This study aims assess feasibility a dual-strip method obtain direct cortical stimulation for continuous real-time subcortical visual pathways simultaneously tumour Methods: Single-centre prospective...
Spinal Cord Injury (SCI) or Acquired Brain (ABI) leads to disability, unemployment, loss of income, decreased quality life and increased mortality. The impact is worse in Low-and Middle-Income Countries (LMICs) due a lack efficient long-term rehabilitative care. This study aims explore the feasibility acceptability telerehabilitation programme Nepal.Prospective cohort community setting following discharge from specialist rehabilitation centre Nepal. Patients with SCI ABI who had previously...
article: Preoperative and intraoperative anatomical-functional mapping in insular glioma surgery: integrated model to improve surgical outcome - Journal of Neurosurgical Sciences 2022 February;66(1):74-5 Minerva Medica Journals
Abstract Background Patient-reported experience measures (PREMs) are a unique measure of patients which can help address the quality care patients. Objective Our aim study is to collect outcomes with our newly navigated transcranial magnetic stimulation patient-reported (nTMS-PREMs) questionnaire among neurosurgical undergoing nTMS. Methods A single-centre prospective nTMS-PREMs 19-item was performed between February 2018 and December on patient referred for nTMS at hospital. The Data...
Madam — The COVID-19 pandemic has challenged the delivery of care worldwide, with many outpatient clinics changing from face-to-face to telephone consultations [1Daggubati L.C. Eichberg D.G. Ivan M.E. Hanft S. Mansouri A. Komotar R.J. et al.Telemedicine for neurosurgical oncology care: lessons learned future during pandemic.World Neurosurg. 2020; 139: e859-e863Crossref PubMed Scopus (42) Google Scholar]. This is particularly challenging in neuro-oncology, where often complex interventions...
BACKGROUND: Uterine prolapse is a significant public health problem in Nepal. The United Nations Population Fund reported global prevalence between 2% to 20% 2006 and approximately 10% for Nepali women. aim of this study explore the self-reported uterine Nepal currently determine unmet surgical need. METHODS: A countrywide survey was done using Surgeons OverSeas Assessment Surgical Need May June 2014. two-stage cluster sampling randomly population-weighted. χ2 tests logistic regression...
We aim to demonstrate intraoperative recording of cerebellar cortical pathways that have not been previously recorded in humans, though imaged.We report 2 cases with neurophysiologic mapping cerebellocortical tracts. Direct electrical stimulation subcortical cerebellum along recordings evoked potential and motor muscle was performed during surgery. MR tractography data from healthy participants were used further illustrate the pathways.Neurophysiologic showed large waveforms potentials...
Objectives Ecchordosis physaliphora (EP) is a benign notochord lesion of the clivus arising from same cell line as chordoma, its malignant counterpart. Although usually asymptomatic, it can cause spontaneous cerebrospinal fluid (CSF) rhinorrhea. Benign notochordal tumor (BNCT) considered another indolent, variant chordoma. aggressive forms chordoma require maximal safe resection followed by proton beam radiotherapy, BNCT and EP be managed with close imaging surveillance without or...
Background: Determination of cerebrospinal fluid-adenosine deaminase (CSF-ADA) activity is a reliable means to differentiate tubercular from non- meningitis. This study was carried out see the range with mean CSF-ADA levels in meningitis various etiologies and if early diagnosis possible based on these levels. Methods: A prospective 140 children admitted Manipal Teaching Hospital, July 2009 – June 2011. Diagnosis established by clinical findings relevant investigations patients were divided...
Abstract Cranial suture diastases are an uncommon clinical entity, with post craniotomy being a previously undescribed finding in literature to our best knowledge. Herein, we report case of 28-year-old adult who underwent second-stage low-grade glioma surgery 7 months after initial surgery. This study presents coronal adjacent the performed craniotomy. After and pathophysiology review, found it be unique that can resemble mechanical stress trauma.