Prajwal Ghimire

ORCID: 0000-0003-2884-956X
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About
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Research Areas
  • Glioma Diagnosis and Treatment
  • Meningioma and schwannoma management
  • Neurosurgical Procedures and Complications
  • Spinal Fractures and Fixation Techniques
  • Head and Neck Surgical Oncology
  • Spine and Intervertebral Disc Pathology
  • Transcranial Magnetic Stimulation Studies
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Intraoperative Neuromonitoring and Anesthetic Effects
  • Advanced Neuroimaging Techniques and Applications
  • Cerebrospinal fluid and hydrocephalus
  • Vascular Malformations Diagnosis and Treatment
  • Radiomics and Machine Learning in Medical Imaging
  • Management of metastatic bone disease
  • Pituitary Gland Disorders and Treatments
  • Intracerebral and Subarachnoid Hemorrhage Research
  • Brain Metastases and Treatment
  • Stroke Rehabilitation and Recovery
  • Neurofibromatosis and Schwannoma Cases
  • Spinal Dysraphism and Malformations
  • Bone Tumor Diagnosis and Treatments
  • Pelvic and Acetabular Injuries
  • Intracranial Aneurysms: Treatment and Complications
  • Oral and Maxillofacial Pathology
  • Telemedicine and Telehealth Implementation

King's College Hospital NHS Foundation Trust
2018-2024

King's College London
2017-2024

King's College Hospital
2017-2024

Neurological Surgery
2024

Tribhuvan University Teaching Hospital
2024

Dhulikhel Hospital
2023

The King's College
2022

Wellcome Centre for Human Neuroimaging
2022

Addenbrooke's Hospital
2021

University of Cambridge
2021

Penfield's motor homunculus describes a caricaturised yet useful representation of the map various body parts on pre-central cortex. We propose supplemental clinically represented areas human in cortex and novel subcortical corticospinal tract map. believe this knowledge is essential for safe surgery patients with eloquent brain lesions. A single-institution retrospective cohort study who underwent craniotomy lesions intraoperative neuromonitoring (cortical subcortical) between 2015 2020 was...

10.1007/s00429-021-02274-z article EN cc-by Brain Structure and Function 2021-04-19
Daniel M. Fountain Jack Henry Susan Honeyman Paul O’Connor Priya Sekhon and 93 more Rory J. Piper Ellie Edlmann Michael G. Martin Gemma Whiting Carole Turner Harry Mee Alexis Joannides Angelos G. Kolias Peter J. Hutchinson Adam Williams Ajay Sinha Alex Leggate Antonio Belli Anuj Bahl Catherine McMahon Christos Tolias Daniel Holsgrove David O’Brien Diederik Bulters Edward St George Giles Critchley Greg James Harith Akram Jonathan Pollock Manjunath Prasad Mario Ganau Mark H. Wilson Mohammed K. Hossain-Ibrahim Peter Bodkin Peter C. Whitfield Ryan Mathew Shabin Joshi Shailendra Achawal Stuart Harrisson Stuart Smith Tim Lawrence Yahia Al-Tamimi Steering Committee Anthony Bell Simon Shaw Paul M. Brennan Ian Anderson Aimun A. B. Jamjoom Alireza Shoakazemi Amad Khan Ammar Kadhim Andrew Edwards-Bailey Anna Bjornson Anthony Roylance Arif Zafar Asad Nabi Asfand Baig Mirza Ajai Chari Basil Yannoulias Charlotte Burford Christopher Yusuf Akhunbay-Fudge Christopher P. Millward Ciaran Scott Hill Damiano G. Barone Daniela Šťastná Debasish Hajra Debayan Dasgupta Debbie Ferguson Edoardo Viaroli Emma Toman Georgios Solomou Josephine Jung Justyna O. Ekert Kamal Makram Yakoub Lava Nozad Mark V. Haley M Petrić Mehdi Khan Melika Akhbari Michael Amoo Milo Hollingworth M.J. Naushahi Mohammed Fadelalla Mueez Waqar Muhammad Mukhtar Khan Mustafa El Sheikh Mutwakil Abdulla Nicola McNulty Prajwal Ghimire Richard Moon Sara Venturini Simon Lammy Soham Bandyopadhyay Vanessa Karavasili Varinder SinghAlg Vasileios Raptopoulos Wai Cheong Soon W. Singleton

There are many questions that remain unanswered regarding outcomes following cranioplasty including the timing of craniectomy as well material used.To establish and evaluate 30-d for all cranial reconstruction procedures in United Kingdom (UK) Ireland through a prospective multicenter cohort study.Patients undergoing insertion or revision between June 1, 2019 November 30, 25 neurosurgical units were included. Data collected include demographics, date indication, date, outcome.In total, 313...

10.1093/neuros/nyab220 article EN Neurosurgery 2021-05-25

Abstract Background Lesions within the primary motor cortex (M1) and corticospinal tract (CST) represent a significant surgical challenge with delicate functional trade-off that should be integrated in overall patient-centered treatment plan. Methods Patients lesions M1 CST preoperative cortical subcortical mapping (navigated transcranial magnetic stimulation [nTMS] tractography), intraoperative mapping, provisional histologic information (smear without 5-aminolevulinic acid [5-ALA]) were...

10.1055/s-0040-1709729 article EN Journal of Neurological Surgery Part A Central European Neurosurgery 2020-05-21

Background: This study has compared the difference in serum bilirubin between patients with gangrenous and non-gangrenous appendicitis. Methods: A prospective analytical of, 141 who underwent appendectomy, from March 2010 to 2011 Manipal Teaching Hospital, Pokhara, Nepal was carried out. Clinico-demographic data, Alvarado’s score, total bilirubin, leucocyte count histopathological report of all cases were collected a prestructured proforma. Comparison appendicitis groups out using...

10.3126/njms.v1i2.6606 article EN Deleted Journal 2012-08-02

Brain tumour surgery in visual eloquent areas poses significant challenges to neurosurgeons and has reported inconsistent results. This is a single-centre prospective cohort study of patients admitted for asleep intra-axial lesions areas. Demographic clinical information, data from tractography evoked potentials (VEPs) monitoring were recorded correlated with outcomes. Thirty-nine included (20 females, 19 males; mean age 52.51 ± 14.08 years). Diffuse intrinsic glioma was noted 61.54%...

10.3390/cancers15153943 article EN Cancers 2023-08-03

Abstract Background Repetitive transcranial magnetic stimulation (rTMS) is established for depression and rehabilitation after stroke emerging cognitive rehabilitation. We sought to evaluate patient carer perceptions toward rTMS neurosurgery. Methods Two surveys were undertaken. Group 1: Patients who received 7 days of motor or language severe postoperative deficits following lesional resection prospectively surveyed on the last day their treatment, as well next kin. 2: had previously been...

10.1093/nop/npae092 article EN Neuro-Oncology Practice 2024-09-25

Introduction: Questionnaire based assessment is a simple, scientific tool to collect responses from individuals and standardised questionnaires can be used assess health care quality of institution. The aim this study was service private hospital on the basis questionnaire-based data collected patients admitted in using (SERVQUAL) questionnaire method.
 Methods: A descriptive cross sectional conducted 203 adult Fishtail Hospital Research Centre, Pokhara, Nepal January 2015 2016....

10.3126/njms.v5i1.36958 article EN Deleted Journal 2020-02-15

Background: The role played by the non-dominant parietal lobe in motor cognition, attention and spatial awareness networks has potentiated use of awake surgery. When this is not feasible, asleep monitoring mapping techniques should be used to achieve an onco-functional balance. Objective: This study aims assess feasibility a dual-strip method obtain direct cortical stimulation for continuous real-time subcortical visual pathways simultaneously tumour Methods: Single-centre prospective...

10.3390/jpm12091478 article EN Journal of Personalized Medicine 2022-09-09

Spinal Cord Injury (SCI) or Acquired Brain (ABI) leads to disability, unemployment, loss of income, decreased quality life and increased mortality. The impact is worse in Low-and Middle-Income Countries (LMICs) due a lack efficient long-term rehabilitative care. This study aims explore the feasibility acceptability telerehabilitation programme Nepal.Prospective cohort community setting following discharge from specialist rehabilitation centre Nepal. Patients with SCI ABI who had previously...

10.1177/11795727221126070 article EN cc-by-nc Rehabilitation Process and Outcome 2022-01-01

article: Preoperative and intraoperative anatomical-functional mapping in insular glioma surgery: integrated model to improve surgical outcome - Journal of Neurosurgical Sciences 2022 February;66(1):74-5 Minerva Medica Journals

10.23736/s0390-5616.21.05242-5 article EN Journal of Neurosurgical Sciences 2022-01-21

Abstract Background Patient-reported experience measures (PREMs) are a unique measure of patients which can help address the quality care patients. Objective Our aim study is to collect outcomes with our newly navigated transcranial magnetic stimulation patient-reported (nTMS-PREMs) questionnaire among neurosurgical undergoing nTMS. Methods A single-centre prospective nTMS-PREMs 19-item was performed between February 2018 and December on patient referred for nTMS at hospital. The Data...

10.1007/s00701-020-04268-y article EN cc-by Acta Neurochirurgica 2020-02-25

Madam — The COVID-19 pandemic has challenged the delivery of care worldwide, with many outpatient clinics changing from face-to-face to telephone consultations [1Daggubati L.C. Eichberg D.G. Ivan M.E. Hanft S. Mansouri A. Komotar R.J. et al.Telemedicine for neurosurgical oncology care: lessons learned future during pandemic.World Neurosurg. 2020; 139: e859-e863Crossref PubMed Scopus (42) Google Scholar]. This is particularly challenging in neuro-oncology, where often complex interventions...

10.1016/j.clon.2020.08.004 article EN other-oa Clinical Oncology 2020-08-20

BACKGROUND: Uterine prolapse is a significant public health problem in Nepal. The United Nations Population Fund reported global prevalence between 2% to 20% 2006 and approximately 10% for Nepali women. aim of this study explore the self-reported uterine Nepal currently determine unmet surgical need. METHODS: A countrywide survey was done using Surgeons OverSeas Assessment Surgical Need May June 2014. two-stage cluster sampling randomly population-weighted. χ2 tests logistic regression...

10.1097/01.aog.0000463729.18256.2a article EN Obstetrics and Gynecology 2015-05-01

We aim to demonstrate intraoperative recording of cerebellar cortical pathways that have not been previously recorded in humans, though imaged.We report 2 cases with neurophysiologic mapping cerebellocortical tracts. Direct electrical stimulation subcortical cerebellum along recordings evoked potential and motor muscle was performed during surgery. MR tractography data from healthy participants were used further illustrate the pathways.Neurophysiologic showed large waveforms potentials...

10.1212/wnl.0000000000200990 article EN Neurology 2022-07-06

Objectives Ecchordosis physaliphora (EP) is a benign notochord lesion of the clivus arising from same cell line as chordoma, its malignant counterpart. Although usually asymptomatic, it can cause spontaneous cerebrospinal fluid (CSF) rhinorrhea. Benign notochordal tumor (BNCT) considered another indolent, variant chordoma. aggressive forms chordoma require maximal safe resection followed by proton beam radiotherapy, BNCT and EP be managed with close imaging surveillance without or...

10.1055/s-0040-1722717 article EN Journal of Neurological Surgery Part B Skull Base 2021-03-12

Background: Determination of cerebrospinal fluid-adenosine deaminase (CSF-ADA) activity is a reliable means to differentiate tubercular from non- meningitis. This study was carried out see the range with mean CSF-ADA levels in meningitis various etiologies and if early diagnosis possible based on these levels. Methods: A prospective 140 children admitted Manipal Teaching Hospital, July 2009 – June 2011. Diagnosis established by clinical findings relevant investigations patients were divided...

10.3126/njms.v1i2.6608 article EN Deleted Journal 2012-08-02

Abstract Cranial suture diastases are an uncommon clinical entity, with post craniotomy being a previously undescribed finding in literature to our best knowledge. Herein, we report case of 28-year-old adult who underwent second-stage low-grade glioma surgery 7 months after initial surgery. This study presents coronal adjacent the performed craniotomy. After and pathophysiology review, found it be unique that can resemble mechanical stress trauma.

10.1093/jscr/rjae004 article EN cc-by Journal of Surgical Case Reports 2024-01-01
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