A5058558191- Cardiovascular Syncope and Autonomic Disorders
- Trauma and Emergency Care Studies
- Cardiac Arrhythmias and Treatments
- Psychosomatic Disorders and Their Treatments
- Heart Rate Variability and Autonomic Control
- Emergency and Acute Care Studies
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Cardiac, Anesthesia and Surgical Outcomes
- Acute Myocardial Infarction Research
- Blood transfusion and management
- Aortic Disease and Treatment Approaches
- Cardiac Arrest and Resuscitation
- Takotsubo Cardiomyopathy and Associated Phenomena
- Aortic aneurysm repair treatments
- X-ray Diffraction in Crystallography
- Higher Education Research Studies
- Crystallization and Solubility Studies
- Acute Ischemic Stroke Management
- ECG Monitoring and Analysis
- Traumatic Brain Injury and Neurovascular Disturbances
- Cardiac Valve Diseases and Treatments
- Education Systems and Policy
- Organ Donation and Transplantation
- Oil Spill Detection and Mitigation
- Abdominal Trauma and Injuries
Edinburgh Royal Infirmary
2016-2025
University of Edinburgh
2015-2025
NHS Lothian
2016-2024
Institute of Occupational Medicine
2023-2024
Royal College of Emergency Medicine
2022
Emerge
2022
Humanitas University
2021
Istituti di Ricovero e Cura a Carattere Scientifico
2021
Glasgow Centre for Population Health
2021
Brookdale Community College
2020
Recenzentów dokumentu z ramienia Komisji ESC ds. Wytycznych Postępowania (CPG) oraz ze strony narodowych towarzystw kardiologicznych wchodzących w skład
There is an urgent need to rapidly distinguish COVID-19 from other respiratory conditions, including influenza, at first-presentation. Point-of-care tests not requiring laboratory- support will speed diagnosis and protect health-care staff. We studied the feasibility of using breath-analysis these conditions with near-patient gas chromatography-ion mobility spectrometry (GC-IMS).
<b>Aim:</b> To assess whether an airway assessment score based on the LEMON method is able to predict difficulty at intubation in emergency department. <b>Methods:</b> Patients requiring endotracheal resuscitation room of a UK teaching hospital between June 2002 and September 2003 were assessed criteria method. At laryngoscopy, Cormack Lehane grade was recorded. An devised assessed. <b>Results:</b> 156 patients intubated during study period. There 114 1 intubations, 29 2 11 3 4 intubations....
The optimal emergency department (ED) evaluation of syncope is uncertain. Research reports from multiple countries suggest extensive practice variation, high costs, and questionable benefit associated with current approaches.1–5 Moreover, only a few the recommendations international guidelines deal ED management.6–8 For example, European Society Cardiology guidelines, which are most inclusive do not address management. This could be due to limited evidence on how stratify risk decide...
There is increasing interest in the timely administration of concentrated sources fibrinogen to patients with major traumatic bleeding. Following evaluation early cryoprecipitate CRYOSTAT 1 trial, we explored use concentrate, which may have advantages more rapid acute haemorrhage. The aims this pragmatic study were assess feasibility concentrate within 45 minutes hospital admission and quantify efficacy maintaining levels ≥ 2 g/L during active We conducted a blinded, randomised,...
Study objectivesThere is limited evidence to guide the emergency department (ED) evaluation and management of syncope. The First International Workshop on Syncope Risk Stratification in Emergency Department identified key research questions methodological standards essential advancing science ED-based syncope research.MethodsWe recruited a multinational panel experts. A preconference survey priorities, which were refined during after conference through an iterative review...
<b>Aims:</b> This study was conducted as a feasibility pilot for the Risk stratification Of Syncope in Emergency department (ROSE) study. The secondary aim to compare performance of our existing emergency (ED) guidelines with clinical decision rules (Osservatorio Epidemiologico sulla Sincope nel Lazio (OESIL) Score and San Francisco Rule; SFSR) at predicting short-term (1 week 1 month) medium-term (3 months) serious outcomes patients syncope presenting ED. <b>Methods:</b> prospective cohort...
SUMMARY The metabolism of 17α-ethynyloestradiol was studied in one man and 16 women. After intravenous or oral administration, 22·6–46·9% the dose excreted urine over a 5-day period. Up to 36% urinary radioactivity may be present unconjugated form with further 64% being extractable after enzymic hydrolysis. Sulphate conjugates formed only 11·4% radioactivity. Semi-quantitation these extracts showed ethynyloestradiol itself major metabolite, accounting for 3·2–8·4% administered fraction...
Patients with palpitations and pre-syncope commonly present to Emergency Departments (EDs) but underlying rhythm diagnosis is often not possible during the initial presentation. This trial compares symptomatic detection rate of a smartphone-based event recorder (AliveCor) alongside standard care versus alone, for participants presenting ED no obvious cause evident at consultation.Multi-centre open label, randomised controlled trial. Participants ≥ 16 years old 10 UK hospital EDs were...
Individuals who sustain a concussion can experience range of symptoms which significantly impact their quality life and functional outcome. This study aims to understand the nature recovery trajectories post-concussion symptomatology by applying an unsupervised machine learning approach data captured from digital health intervention (HeadOn). As part 35-day program, patients complete daily symptom diary rates 8 symptoms. Symptom were analysed using K-means clustering categorize based on...
Acute aortic syndromes and other acute events are commonly misdiagnosed associated with high mortality morbidity. There is need for a blood-based biomarker to indicate the acutely unstable aorta. Plasma cell-free DNA (cfDNA) an established diagnostic marker in prenatal testing cancer. Its use as potential disease remains be demonstrated. We found that plasma short-fragment (50-700bp) cfDNA concentration significantly increased patients both chronic compared several control groups, versus...