A5082055582- Traumatic Brain Injury and Neurovascular Disturbances
- Neurosurgical Procedures and Complications
- Glioma Diagnosis and Treatment
- Spinal Dysraphism and Malformations
- Cerebrospinal fluid and hydrocephalus
- Intracerebral and Subarachnoid Hemorrhage Research
- Congenital gastrointestinal and neural anomalies
- Congenital Diaphragmatic Hernia Studies
- Pituitary Gland Disorders and Treatments
- Cerebral Venous Sinus Thrombosis
- Medical Malpractice and Liability Issues
- Cardiac, Anesthesia and Surgical Outcomes
- Advanced MRI Techniques and Applications
- Cannabis and Cannabinoid Research
- COVID-19 and healthcare impacts
- Frequency Control in Power Systems
- Intracranial Aneurysms: Treatment and Complications
- Patient Safety and Medication Errors
- Anesthesia and Neurotoxicity Research
- Cerebrovascular and Carotid Artery Diseases
- Heparin-Induced Thrombocytopenia and Thrombosis
- Anorectal Disease Treatments and Outcomes
- Case Reports on Hematomas
- Anesthesia and Sedative Agents
- Meta-analysis and systematic reviews
Ninewells Hospital
2024
Royal Victoria Infirmary
2019-2023
University of Colorado Anschutz Medical Campus
2020-2023
Newcastle upon Tyne Hospital
2021-2023
Royal Victoria Hospital
2023
Great North Children's Hospital
2023
Great Ormond Street Hospital for Children NHS Foundation Trust
2022
Addenbrooke's Hospital
2022
Society of British Neurological Surgeons
2022
Boston Biomedical (United States)
2022
Insertion of a ventriculoperitoneal shunt for hydrocephalus is one the commonest neurosurgical procedures worldwide. Infection implanted affects up to 15% these patients, resulting in prolonged hospital treatment, multiple surgeries, and reduced cognition quality life. Our aim was determine clinical cost-effectiveness antibiotic (rifampicin clindamycin) or silver shunts compared with standard at reducing infection.In this parallel, multicentre, single-blind, randomised controlled trial, we...
Chronic subdural hematoma (CSDH) is a common neurological condition; surgical evacuation the mainstay of treatment for symptomatic patients. No clear evidence exists regarding impact timing surgery on outcomes. We investigated factors influencing time to and its outcomes interest.
Abstract The Dex-CSDH trial is a randomised, double-blind, placebo-controlled of dexamethasone for patients with symptomatic chronic subdural haematoma. commenced an internal pilot, whose primary objective was to assess the feasibility multi-centre recruitment. Primary outcome data collection and safety were also assessed, whilst maintaining blinding. We aimed recruit 100 from United Kingdom Neurosurgical Units within 12 months. Trial participants randomised 2-week course or placebo in...
This study sought to identify differences in cannabis use and perceptions about mitigating seizure-related symptoms patients with epilepsy, evaluate these patterns between drug-resistant versus pharmacoresponsive epilepsy. A collection of self-report surveys completed by epilepsy (n = 76) were used retrospectively compare those regarding 1) proportion who cannabis, 2) frequency use, 3) method 4) reason for use. Cochran-Armitage test trend indicated that a higher the group more frequently...
OBJECTIVE Perioperative management of hydrocephalus in children with posterior fossa tumors (PFTs) remains challenging. The modified Canadian Preoperative Prediction Rule for Hydrocephalus (mCPPRH) has been previously described as a useful tool predicting which are at higher risk permanent following PFT resection and can be used guiding treatment. aim this study was to externally validate predictive model. METHODS A retrospective review the treated single unit conducted, recording all mCPPRH...
Objective Venous sinus compromise (VSC) of the sigmoid can manifest as either venous thrombosis, stenosis, or a combination two. It may occur following retro and presigmoid craniotomy, even in absence overt intraoperative injury. Currently, optimal management VSC perioperative period is not well established. We report our incidence skull base surgery around sinus. Patients Methods A retrospective chart review all patients undergoing presigmoid, retrosigmoid, combined approach by senior...
Abstract Background In recent years an increasing number of patients with cerebral metastasis (CM) have been referred to the neuro-oncology multidisciplinary team (NMDT). Our aim was obtain a national picture CM referrals assess referral volume and quality factors affecting NMDT decision making. Methods A prospective multicenter cohort study including all adult 1 or more conducted. Data were collected in neurosurgical units from November 2017 February 2018. Demographics, primary disease,...
Background Although idiopathic aqueductal stenosis is a congenital disorder, some patients present in adulthood. Many theories have tried to account for the late-onset presentation; however, aetiology remains uncertain. This study aimed investigate clinical presentation, management, and outcomes of with (LIAS) managed at our centre. Methodology A retrospective diagnosis LIAS centre between 1996 2018 was undertaken. Data on imaging, were retrieved from patient records radiology reports....
Abstract Purpose Post-operative MRI is used to assess extent of resection, monitor treatment response and detect progression in high-grade glioma. However, compliance with accepted guidelines for follow-up MRI, impact on management/outcomes unclear. Methods Multi-center, retrospective observational cohort study patients confirmed WHO grade 4 glioma (August 2018-February 2019) receiving oncological treatment. Primary objective: investigate surveillance practice recommendations from NICE...
The impact of Covid-19 on surgical patients worldwide has been substantial. In the United Kingdom (UK) and Republic Ireland (RoI), first wave pandemic occurred in March 2020. aims this study were to: (1) evaluate volume neurosurgical operative activity levels, infection rate mortality April 2020 with a retrospective cross-sectional cohort conducted across 16 UK RoI centres, (2) compare patient outcomes single institution April-June comparative 2019. Across RoI, 818 included. There 594...
Background Vaccines have been key in preventing COVID-19 infections and the AstraZeneca (AZ) vaccine has widely used. However, increased rates of thromboembolic events were identified recipients and, subsequently, a syndrome vaccine-induced immune thrombotic thrombocytopaenia (VITT) was described whereby presented with venous sinus thromboses, haemorrhagic infarctions, – consequently raised intracranial pressure. National guidance recommended decompressive craniectomies for refractory...
<h3>Objective</h3> We identified a lack of formal neurosurgical induction or training for rotating paediatric doctors. This could potentially adversely affect patient outcomes because trainees generally are unfamiliar with common presentations and complications. developed new programme, Basic Neurosurgery For Paediatricians (BNFP) sought to quantitatively assess its impact. <h3>Methods</h3> started pilot study in our Trust distributed anonymous questionnaires 20 commencing their rotation....
Background Chronic subdural hematoma (CSDH) is a common neurological condition; surgical evacuation the mainstay of treatment for symptomatic patients. No clear evidence exists regarding impact timing surgery on outcomes. We investigated factors influencing time to and its outcomes interest. Methods Patients with CSDH who underwent burr-hole craniostomy were included. This subset data from prospective observational study conducted in UK. Logistic mixed modelling was performed examine...