A5047780525- Head and Neck Surgical Oncology
- Cerebrospinal fluid and hydrocephalus
- Glioma Diagnosis and Treatment
- Meningioma and schwannoma management
- Neurosurgical Procedures and Complications
- Bone Tumor Diagnosis and Treatments
- Traumatic Brain Injury and Neurovascular Disturbances
- Spinal Fractures and Fixation Techniques
- Pituitary Gland Disorders and Treatments
- Intracerebral and Subarachnoid Hemorrhage Research
- Management of metastatic bone disease
- Acute Ischemic Stroke Management
- Spine and Intervertebral Disc Pathology
- Reconstructive Surgery and Microvascular Techniques
- Sinusitis and nasal conditions
- Medical Imaging and Analysis
- Diversity and Career in Medicine
- Surgical Simulation and Training
- Neurofibromatosis and Schwannoma Cases
- Anatomy and Medical Technology
- Surgical Sutures and Adhesives
- Facial Nerve Paralysis Treatment and Research
- Vascular Malformations Diagnosis and Treatment
- Congenital gastrointestinal and neural anomalies
- Ocular Diseases and Behçet’s Syndrome
Ninewells Hospital
2023-2025
NHS Tayside
2023-2024
National Health Service
2024
Ain Shams University
2024
King's College Hospital
2021-2022
King's College London
2022
King's College Hospital NHS Foundation Trust
2020-2022
Royal Victoria Infirmary
2016-2021
Newcastle upon Tyne Hospitals NHS Foundation Trust
2019-2021
Newcastle upon Tyne Hospital
2014-2021
OBJECTIVE Foot drop is characterized by weakness in ankle dorsiflexion, primarily due to failure of activation dorsiflexor muscles secondary neural compromise. The aim this study was evaluate surgical outcomes for unilateral painful foot lumbar disc herniation, specifically excluding cases with cauda equina syndrome. METHODS This retrospective spanned 7 centers, focusing on adult patients who underwent discectomies from September 2011 2022 (Medical Research Council [MRC] grade ≤ 3). Clinical...
The Koos grading scale is a frequently used classification system for vestibular schwannoma (VS) that accounts extrameatal tumor dimension and compression of the brain stem. We propose an artificial intelligence (AI) pipeline to fully automate segmentation VS from MRI improve clinical workflow facilitate patient management.We method does not only rely on available images but also automatically generated segmentations. Artificial neural networks were trained tested based manual segmentations...
This study aimed to conduct a thorough dosimetric comparison between two advanced radiotherapy techniques, Intensity-Modulated Radiation Therapy (IMRT) and Volumetric-Modulated Arc (VMAT), ascertain the superior modality in terms of dose distribution organ-at-risk sparing for rectal cancer patients. Thirty-three patients with ECOG performance status 1, aged 18 60 years, diagnosed Stage II III cancer, were included this prospective study. Each patient underwent treatment planning IMRT VMAT...
Abstract Background Neurosurgery can be a daunting career choice for medical students, with preparation trainee application often being inaccessible and expensive. This article describes student-led neurosurgical skills event supported by local neurosurgery faculty members. Such was designed to offer means bridge this gap providing an opportunity practice techniques in simulation, learn about what involves. Methods Pre- postskills laboratory surveys were used ascertain the baseline...
Objectives Chordomas are rare, slow-growing, and osteo-destructive tumors of the primitive notochord. There is still contention in literature as to optimal management chordoma. We conducted a systematic review surgical chordoma along with our 10-year institutional experience. Design A search was performed October 2020 by using MEDLINE EMBASE for articles relating clival chordomas. also searched all adult patients surgically treated primary chordomas at institute between 2009 2019....
The growth characteristics of vestibular schwannomas (VSs) under surveillance can be studied using a Bayesian method risk stratification by time after onset, allowing dynamic evaluations risks. There is no consensus on the optimum strategy in terms frequency and duration, particularly for long-term In this study, conditional probability new VS was reported patients 5 years demonstrated nongrowth. This allowed modeling risks, creation an evidence-based protocol, proposal cost-benefit analysis...
Neuro-Behçet’s disease (NBD) is a serious manifestation of Behçet’s (BD) and can affect either the central or peripheral nervous systems, both. It occurs in 10–50% patients with BD. We report on patient an unusual intraparenchymal lesion, initially thought to be brain tumour. Histological examination revealed vasculitis consistent Clinicians should include NBD as differential diagnosis when considering isolated inflammatory intracranial lesion.
OBJECTIVE Freehand external ventricular drain (EVD) insertion is associated with a high rate of catheter misplacement. Image-guided EVD placement neuronavigation or ultrasound has been proposed as safer, more accurate alternative potential to facilitate proper and reduce malfunction risk. This study aimed determine the impact image-guided on tip position functionality. METHODS secondary analysis data set from prospective, multicenter study. Data were collated for placements undertaken in...
Background A temporo-sphenoidal encephalocoele occurs when temporal lobe herniates through a defect in the greater wing of sphenoid bone into air sinus. The natural history is not well-understood, though presentation adulthood with CSF rhinorrhoea and/or meningitis typical. Lateral pneumatisation sinus and elevated BMI may be contributory.
Background Although idiopathic aqueductal stenosis is a congenital disorder, some patients present in adulthood. Many theories have tried to account for the late-onset presentation; however, aetiology remains uncertain. This study aimed investigate clinical presentation, management, and outcomes of with (LIAS) managed at our centre. Methodology A retrospective diagnosis LIAS centre between 1996 2018 was undertaken. Data on imaging, were retrieved from patient records radiology reports....
Glioblastoma multiforme (GBM), the most aggressive primary brain tumour, exhibits low survival rates due to its rapid growth, infiltrates surrounding tissue, and is highly resistant treatment. One major challenge oedema infiltration, a fluid build$-$up that provides path for cancer cells invade other areas. MRI resolution insufficient detect these infiltrating cells, leading relapses despite chemotherapy radiotherapy. In this work, we propose new multiscale mathematical modelling method,...
Abstract Background Medial sphenoid wing meningiomas are best treated through pterional craniotomy, as craniotomy provides wide and multidirectional exposure of the anterior middle cranial fossa. Anterior clinoidectomy can increase potential. To delineate role (AC) in standard approach evaluation operability score measures (manoeuvrability arc, depth surgical field, angle attack). All patients with inner sphenoidal meningioma who underwent microsurgical excision between February 2022 October...
Abstract Background Sarcopenia, characterized by age-related muscle loss, is common in patients with liver cirrhosis (LC). LC's metabolic burdens include protein and energy metabolism disorders, potentially leading to secondary sarcopenia. This study explores the prognostic role of serum myostatin levels predicting hepatocellular carcinoma (HCC) development individuals alcoholic (ALC). Aim Work The aim this investigate performance on HCC Patients Methods We conducted a retrospective...
Glioblastoma multiforme (GBM), the most aggressive primary brain tumour, exhibits low survival rates due to its rapid growth, infiltrates surrounding tissue, and is highly resistant treatment. One major challenge oedema infiltration, a fluid build-up that provides path for cancer cells invade other areas. MRI resolution insufficient detect these infiltrating cells, leading relapses despite chemotherapy radiotherapy. In this work, we propose new multiscale mathematical modelling method,...
Objectives Cerebrospinal fluid (CSF) leak following endoscopic transsphenoidal surgery (TSS) remains a challenge and is associated with high morbidity. We perform primary repair f at in the pituitary ossa further fat s phenoid sinus (FFS). compare efficacy of this FFS technique other methods systematic review. Design, Patients, Methods This retrospective analysis patients undergoing standard TSS from 2009 to 2020, comparing incidence significant postoperative CSF rhinorrhea (requiring...
Cerebrospinal fluid (CSF) rhinorrhoea is a leakage of CSF from the subarachnoid space through frontal, sphenoidal or ethmoidal sinuses to nose. In this study we present our experience in endoscopic repair 55 cases who were operated endoscopically trans-nasally. The success rate procedure preventing leak after first was 85.5% which increased 90.9% following second patients with persistent leak. Endoscopic approach cerebrospinal remarkably well tolerated and complication rates are low,...
Ventriculo-peritoneal shunt malfunction is a common neurosurgical presentation, which may occur as result of disconnection at the level valve. Previous studies assessing ligatures have suggested that constrictor knot stronger in securing ligature compared to surgeon's knot. Our study ability each secure tubing valve.A medtronic valve was secured peritoneal catheter using versus constrictor's The weight and subsequent force (N) required pull off site were recorded.The mean pull-off 11.7 N for...