- Parkinson's Disease Mechanisms and Treatments
- Neurological disorders and treatments
- Spinal Dysraphism and Malformations
- Musculoskeletal pain and rehabilitation
- Anesthesia and Pain Management
- Lymphoma Diagnosis and Treatment
- Genetic Neurodegenerative Diseases
- CNS Lymphoma Diagnosis and Treatment
- Cerebrospinal fluid and hydrocephalus
- Glioma Diagnosis and Treatment
- COVID-19 Clinical Research Studies
- COVID-19 epidemiological studies
- Traumatic Brain Injury and Neurovascular Disturbances
- Transcranial Magnetic Stimulation Studies
- Spine and Intervertebral Disc Pathology
- COVID-19 and healthcare impacts
King's College Hospital NHS Foundation Trust
2021-2023
Kings Health Partners
2021-2022
King's College Hospital
2021
National Health Service
2021
OBJECTIVE Foot drop is characterized by weakness in ankle dorsiflexion, primarily due to failure of activation dorsiflexor muscles secondary neural compromise. The aim this study was evaluate surgical outcomes for unilateral painful foot lumbar disc herniation, specifically excluding cases with cauda equina syndrome. METHODS This retrospective spanned 7 centers, focusing on adult patients who underwent discectomies from September 2011 2022 (Medical Research Council [MRC] grade ≤ 3). Clinical...
Introduction Europe was the epicentre of COVID-19 pandemic in March 2020, with highest number cases and deaths between April. In May, infection numbers registered a fall followed by second new rise, not proportionally reflected an increase deaths. We aimed to investigate relationship disease prevalence fatality rate (IFR), intensive care unit (ICU) hospital admissions over time, develop predictive model, as well appraising potential contributing factors underpinning this complex...
Colloid cysts, although benign, may occasionally cause obstructive hydrocephalus and sudden death. Reliable prognostic factors for symptomatic progression have been sought, with heterogenous results. We conducted a retrospective review of all cases colloid cysts the third ventricle managed at our center between 2009 2019. Clinical neuroimaging characteristics were analyzed using logistic regression in relation to status hydrocephalus. The cutoff values outcome prediction calculated receiver...
Central nervous system lymphoma (CNSL) represents one of the most aggressive forms extranodal lymphoma. The gold standard for CNSL diagnosis remains stereotactic biopsy, with a limited role cytoreductive surgery that has not been supported by historical data. Our study aims to provide comprehensive overview neurosurgery's in systemic relapsed and primary CNSL, an emphasis on impact management survival. This is single center retrospective cohort data collected between August 2012 2020,...
Parkinson’s disease (PD) is a complex neurodegenerative disorder, leading to impairment of various neurological faculties, including motor, planning, cognitivity, and executive functions. Motor- non-motor symptoms the may intensify patient’s restrictions performing usual tasks daily living, driving. Deep Brain Stimulation (DBS) associated with optimized clinical treatment has been shown improve quality life, in PD. In most countries, there are no specific guidelines concerning minimum safety...