A5075309805- Neurological disorders and treatments
- Vascular Malformations Diagnosis and Treatment
- Intracranial Aneurysms: Treatment and Complications
- Traumatic Brain Injury and Neurovascular Disturbances
- Parkinson's Disease Mechanisms and Treatments
- Spinal Fractures and Fixation Techniques
- Glioma Diagnosis and Treatment
- Meningioma and schwannoma management
- Cerebrospinal fluid and hydrocephalus
- Genetic Neurodegenerative Diseases
- Advanced MRI Techniques and Applications
- Sperm and Testicular Function
- Sepsis Diagnosis and Treatment
- Emergency and Acute Care Studies
- Spinal Dysraphism and Malformations
- Central Venous Catheters and Hemodialysis
- Radiomics and Machine Learning in Medical Imaging
- Head and Neck Surgical Oncology
- Hemostasis and retained surgical items
- Sarcoidosis and Beryllium Toxicity Research
- Cervical and Thoracic Myelopathy
- Moyamoya disease diagnosis and treatment
- Autism Spectrum Disorder Research
- Cerebrovascular and Carotid Artery Diseases
- Artificial Intelligence in Healthcare and Education
Queen's Hospital
2010-2024
Queen Mary University of London
2021-2024
Turing Institute
2019-2024
The Alan Turing Institute
2023-2024
University of Crete
2024
Queen's Hospital
2019-2023
Barking, Havering And Redbridge University Hospitals NHS Trust
2017-2023
Damascus University
2023
University Hospital of Heraklion
2021
National Hospital for Neurology and Neurosurgery
2011-2014
Cauda equina syndrome (CES) results from nerve root compression in the lumbosacral spine, usually due to a prolapsed intervertebral disc. Evidence for management of CES is limited by its infrequent occurrence and lack standardised clinical definitions outcome measures. This prospective multi-centre observational cohort study adults with UK. We assessed presentation, investigation, management, all Core Outcome Set domains up one year post-operatively using clinician participant reporting....
Study Type – Therapy (RCT) Level of Evidence 1b OBJECTIVE To evaluate the effects phosphodiesterase‐5 inhibitors (PDE5‐i) on Leydig cell secretory function (LCSF). PATIENTS AND METHODS In all, 75 men with oligoasthenospermia were treated daily for 12 weeks either vardenafil (23 men, group A), sildenafil (25 B) or l ‐carnitine (26 C); a further 22 (group D) received no treatment. Serum levels insulin‐like‐3 peptide (INSL3) evaluated before and after end treatment in each groups A, B C,...
Clinical coding is the translation of documented clinical activities during an admission to a codified language. Healthcare Resource Groupings (HRGs) are derived from data and used calculate payment hospitals in England, Wales Scotland conduct national audit benchmarking exercises. Coding error-prone process understanding its accuracy within neurosurgery critical for financial, organizational governance purposes. We undertook multidisciplinary neurosurgical accuracy. Neurosurgeons trained...
Background Deep brain stimulation (DBS) is a well-recognised treatment for advanced Parkinson's disease (PD) patients. Structural alterations of the white matter can correlate with progression and act as biomarker DBS therapy outcomes. This study aims to develop machine learning-driven predictive model patient selection using whole-brain radiomics common clinical variables. Methodology A total 120 PD patients underwent subthalamic nucleus. Their effect was assessed at one-year follow-up...
Abstract The Dex-CSDH trial is a randomised, double-blind, placebo-controlled of dexamethasone for patients with symptomatic chronic subdural haematoma. commenced an internal pilot, whose primary objective was to assess the feasibility multi-centre recruitment. Primary outcome data collection and safety were also assessed, whilst maintaining blinding. We aimed recruit 100 from United Kingdom Neurosurgical Units within 12 months. Trial participants randomised 2-week course or placebo in...
Objective We report the utilisation and impact of a novel triage-based electronic screening tool (eST) combined with clinical assessment to recognise sepsis in paediatric ED. Methods An was implemented EDs two large UK secondary care hospitals between June 2018 January 2019. Patients eligible for were children < 16 years ages excluding those minor injuries or who brought directly resuscitation. Subsequently, retrospective evaluation performed determine performance alone combination after...
We report an unusual case of a patient with ventriculo-pleural shunt presenting signs and symptoms heart failure due to massive pericardial effusion. Imaging revealed the distal catheter end within middle mediastinum have migrated from pleural space. The underwent revision procedure resulting in complete resolution pathology. intend draw reader's attention this rare presentation malfunction.
We describe a rare case of foreign body granuloma associated with silk suture material in 36-year-old patient 20 years after craniotomy for traumatic subdural haematoma. The use neurosurgery is discussed.
Context: Surgery for the rheumatoid cervical spine has been shown to stabilize unstable spine; arrest/improve progression of neurological deficit, help neck pain, and possibly decelerate degenerative disease process. Operative intervention significantly changed over last 30 years. Aims: The purpose this study was review all cases requiring surgical in a single unit Materials Methods: A prospectively-maintained database retrospectively searched spine, leading indications, imaging, Ranawat...
Abstract Background Parkinson’s disease (PD) is the second most common neurodegenerative disorder and continues to affect an increasingly large portion of world’s population. Limitations medical treatment PD with levodopa have led deep brain stimulation (DBS) therapy being used alleviate symptoms in advanced patients. Despite its efficacy motor PD, DBS has been noted lead worsening cognitive outcomes a percentage cases. There currently no predictive model for individual patient post DBS. Aim...
Neurosurgery: August 2010 - Volume 67 Issue 2 p 551 doi: 10.1227/01.NEU.0000387019.68059.C8
A 19-year old 11 weeks pregnant woman was admitted to Hurstwood Park Neurosciences Centre following a road traffic crash. The patient front seat passenger wearing belt when the car hit on side by an oncoming vehicle at 30 mph (airbags deployed). She able walk out of but noticed immediate neck pain, stiffness and torticollis. had history mild cerebral palsy with degree learning difficulty weakness right her body since birth (full term pregnancy, normal delivery). No further neurological...