Rosaline Mishra

ORCID: 0000-0001-5611-8831
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Research Areas
  • Polymer Nanocomposite Synthesis and Irradiation
  • Advanced Drug Delivery Systems
  • Hydrogels: synthesis, properties, applications
  • Drug-Induced Hepatotoxicity and Protection
  • Polymer crystallization and properties
  • Natural Antidiabetic Agents Studies
  • Botanical Research and Applications
  • Nanoparticle-Based Drug Delivery
  • Thyroid Cancer Diagnosis and Treatment
  • Pharmacological Effects of Natural Compounds
  • Radiation Effects in Electronics
  • Pharmacology and Obesity Treatment
  • Medicinal Plants and Neuroprotection
  • Lipid Membrane Structure and Behavior
  • Genetic Syndromes and Imprinting
  • Blockchain Technology Applications and Security
  • Ethnobotanical and Medicinal Plants Studies
  • Acne and Rosacea Treatments and Effects
  • Radiation Effects and Dosimetry
  • Polysaccharides Composition and Applications
  • Intravenous Infusion Technology and Safety
  • Phytochemicals and Medicinal Plants
  • Advanced biosensing and bioanalysis techniques
  • Graphene and Nanomaterials Applications
  • Plant-Derived Bioactive Compounds

Metro Health Hospital
2023

Uttarakhand Technical University
2021

Institute of Management Technology
2017-2018

National Hospital
2009

P. D. Hinduja Hospital and Medical Research Centre
2009

North Eastern Hill University
2001-2002

Abstract Background Biosensors are tools that products of amalgamation biological constituents and physicochemical elements so as to detect analytes, based on signal production which is measurable. Thus here we can see an assimilation biology microelectronics. Keeping a track biochemical processes in human system essential; thus, there increasing need for extremely sensitive economical devices make precise diagnosis personalised medication treatment possible. Objective This review focuses...

10.1186/s42269-025-01308-4 article EN cc-by Bulletin of the National Research Centre/Bulletin of the National Research Center 2025-02-14

Diabetic neuropathy is a debilitating manifestation of long-term diabetes mellitus. The present study explored the effects roots Rubia cordifolia L. (R. L.) in Wistar rat model for diabetic and possible neuroprotective, antidiabetic, analgesic mechanisms underlying this effect.Rats were divided into five experimental groups. An amount 0.25% carboxy methyl cellulose (CMC) saline streptozotocin (STZ) (60 mg/kg) was given to group 1 2, respectively. Group 3 treated with STZ glibenclamide...

10.3390/ph16111586 article EN cc-by Pharmaceuticals 2023-11-09

Gentamicin-induced nephrotoxicity limits its therapeutic use as an effective aminoglycoside. Herbal drugs have a distinct place in the world of pharmaceuticals since they are safe, effective, and cost-efficient.

10.1080/01480545.2024.2388324 article EN Drug and Chemical Toxicology 2024-08-19

Context: Gymnema sylvestre (GS) is a plant species that mostly found in the tropical regions of Asia, Africa and Australia; it widespread India Sri Lanka. According to various scientific studies, GS contains chemical constituent known suppress taste for sugar; this kindled our interest study extracts their antidiabetic potential.
 Aim: The current emphasizes screening leaves using chloroform, ethyl acetate, water phytoconstituents evaluating Antidiabetic property. All individual...

10.31069/japsr.v6i2.06 article EN cc-by-nc Journal of Applied Pharmaceutical Sciences and Research 2023-10-13

Abstract In the present work, effect of 2MeV electron irradiation Polyallyldiglycol Carbonate (PADC) has been studied for different doses. The optical band-gap derived from UV-Vis spectra was found to decrease with an increase in dose. Fourier Transformed IR analysis showed a transmittance due irradiation. Thermogravimetric irradiated samples revealed thermal stability Differential scanning calorimetry done study dose dependent phase transformations samples. X-ray diffraction supported...

10.1080/10420150108214040 article EN Radiation effects and defects in solids 2001-06-01

A systematic investigation of 62 r MeV proton irradiated Poly(ethylene terephthalate) (PET) has been carried out using Fourier Transformed Infrared Spectroscopy, thermogravimetric analysis, differential scanning calorimetry and X-ray diffraction spectroscopy. The experiments revealed a restoration the crystalline matrix simultaneous decrease in thermal stability polymer as function dose, indicating that PET underwent both degradation cross-linking by irradiation.

10.1080/10420150214037 article EN Radiation effects and defects in solids 2002-01-01

A systematic investigation of 62 r MeV proton irradiated Poly(ethylene terephthalate) (PET) has been carried out using Fourier Transformed Infrared Spectroscopy, thermogravimetric analysis, differential scanning calorimetry and X-ray diffraction spectroscopy. The experiments revealed a restoration the crystalline matrix simultaneous decrease in thermal stability polymer as function dose, indicating that PET underwent both degradation cross-linking by irradiation.

10.1080/10420150214038 article EN Radiation effects and defects in solids 2002-01-01

Liver is the principle organ for metabolism of various drugs, endotoxins. Hepatotoxicity one reversible conditions. Drugs are an vital cause liver injury. Drug-induced injury to can mimic any form acute or chronic disease. The action cytochrome P450 induce liver, through which drug will break down into electrophiles free radicals. These spontaneous metabolites covalently bind protein and unsaturated fatty acids lipid peroxidation, respectively. clinical presentation damage may be either...

10.30750/ijpbr.6.3.9 article EN Indian Journal of Pharmaceutical and Biological Research 2018-09-30

The whole plant of Coriandrum sativum L. is used in variety diseases including renal ailments throughout the world. aim this study was to find out nephroprotective activity against Gentamicin (GM) induced toxicity. Sixty Wistar albino rats were divided into ten groups. GM injected i.p, at dose 100 mg/kg for 10 consecutive days inducing nephrotoxicity. Metformin (MF) given orally two different doses i.e., 50 and either after nephrotoxicity or along with fresh leaf extract 2 ml/day 28 day ....

10.1080/22311866.2019.1707709 article EN Journal of Biologically Active Products from Nature 2019-11-02

Background: Hypercium perforatum is a natural medicinal plant with many therapeutic effects. The low solubility and bioavailability limits the efficacy of herbal preparations. Purpose: aim this work was to encapsulate into nanophytosomes (NPs) assess nanocarrier in neuropathic pain induced by partial sciatic nerve ligation (PSNL).Method: Particle size, zeta potential, encapsulation efficiency loading capacity evaluated. DSC confirmed physical chemical interaction between extract (HPE)...

10.2139/ssrn.4342190 article EN SSRN Electronic Journal 2023-01-01

This work aimed to encapsulate Hypericum perforatum extract (HPE) into nanophytosomes (NPs) and assess the therapeutic efficacy of this nanocarrier in neuropathic pain induced by partial sciatic nerve ligation (PSNL).Hydroalcoholic was prepared encapsulated NPs thin layer hydration method. Particle size, zeta potential, TEM, differential scanning calorimetry (DSC), entrapment efficiency (%EE), loading capacity (LC) were reported. The biochemical histopathological examinations measured...

10.1080/02652048.2023.2215306 article EN Journal of Microencapsulation 2023-05-16
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