A5023236416- Hemoglobinopathies and Related Disorders
- Iron Metabolism and Disorders
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Pregnancy and preeclampsia studies
- Bone and Joint Diseases
- Venous Thromboembolism Diagnosis and Management
- Inflammatory Biomarkers in Disease Prognosis
- Blood transfusion and management
- Blood donation and transfusion practices
- Blood groups and transfusion
- Gestational Diabetes Research and Management
- HIV, Drug Use, Sexual Risk
- Adolescent Sexual and Reproductive Health
- HIV/AIDS Research and Interventions
- Artificial Intelligence in Healthcare and Education
- Blood Coagulation and Thrombosis Mechanisms
- COVID-19 diagnosis using AI
- Statistical Methods and Inference
- Machine Learning in Healthcare
- Statistical Methods in Clinical Trials
- Birth, Development, and Health
- Neurological and metabolic disorders
- Opioid Use Disorder Treatment
- Poverty, Education, and Child Welfare
- Advanced Statistical Process Monitoring
Nnamdi Azikiwe University
2020-2025
Nnamdi Azikiwe University Teaching Hospital
2022-2024
Chukwuemeka Odumegwu Ojukwu University
1970-2021
University of Port Harcourt Teaching Hospital
2014
University of Port Harcourt
2013
Abstract Objectives Transfusion-transmitted infections are a serious complication of blood transfusion. Devising means detecting at-risk donors may be beneficial in low- and middle-income countries such as Nigeria. We sought to determine the impact ABO group on prevalence transfusion transmitted infections. Methods A retrospective observational study was carried out at bank Chukwuemeka Odumegwu Ojukwu University Teaching Hospital Nigeria using data from donors. Information retrieved about...
Abstract Background and objective Antimicrobial resistance (AMR) is a global crisis, however, relatively little known regarding its impact in chronic respiratory disease the specific challenges faced by healthcare workers across world this field. We aimed to assess worker views on they face AMR disease. Methods An online survey was sent globally working through European Respiratory Society clinical research collaboration (AMR-Lung) focussed lung Responses from different geographic regions...
Objective To obtain multicentre data on the prevalence of normal, high or conditional (intermediate) blood velocity in cerebral arteries among children with sickle cell disease (SCD) Nigeria. Design A prospective observational study five tertiary healthcare institutions. By transcranial Doppler (TCD) ultrasonography, artery peak systolic (PSV) was determined 193 SCD and time averaged mean maximum (TAMMV) a different cohort 115 children. This design to make findings relevant hospitals TCD...
Background: Studies have indicated neutrophil/lymphocyte ratio (NLR), Platelet/Lymphocyte (PLR), and platelet/neutrophils (PNR) to be inflammatory markers. The correlation of these values in infants hypertensive mothers has not been investigated.Aim: To investigate the relationship between NLR, PLR, PNR neonates women with disease pregnancy neonatal APGAR scores birth weight.Methodology: Cord blood samples 200 collected counts ratios obtained.Results: NLR babies was 0.865 1.42 control group...
HIV transmission is still a public health concern in sub-Saharan Africa; disclosure an effective tool for its prevention, contact tracing and treatment. We aimed to evaluate the behaviours of adult HIV-positive patients receiving antiretroviral therapy (ART) University Port Harcourt Teaching Hospital, identify major challenges bid develop ways improve this practice environment. Patients ART centre were interviewed using interviewer-administered questionnaire. A total 250 clients over three...
Background: Sickle cell Diseases (SCD) is a genetic disorder.It the most common disorder affecting black race worldwide.It carries high mortality and morbidity when not promptly properly managed.Early detection key to improving quality of life people living with sickle disease especially in childhood.It has resulted reduction rate SCD <1% developed countries through new-born screening but this yet be achieved developing countries.Objective: To share experience at COOUTH Awka.To determine...
Abstract Presentation Date: 6/9/2024 Start Time: 3:00:00 PM Background Sickle cell disease (SCD) presents a formidable healthcare challenge, with stroke being significant complication. The gold standard for risk assessment is transcranial doppler ultrasound (TCD). However, resource constraints often limit TCD availability. This study explores the potential of platelet-neutrophil ratio (PNR) as cost-effective and an additional tool assessing in SCD patients. Methods was retrospective...
Abstract Presentation Date: 6/9/2024 Start Time: 4:15:00 PM Background Sickle cell disease (SCD) is an inherited hemolytic anemia, common in developing countries like Nigeria. Platelet to neutrophil ratio inflammatory marker used determine outcome some conditions. Developing a simple but effective means of monitoring SCD patients on hydroxyurea may be beneficial the world, where poverty makes it difficult adequately manage and follow up patients. Methods This was retrospective study whose...
Sickle Cell Anaemia (SCA) management requires regular monitoring which is often challenging in resource-limited settings. This study explores the novel use of Platelet-Neutrophil Ratio (PNR) as a comprehensive tool SCA. We present case Jehovah's Witness child with SCA, managed hydroxyurea for elevated transcranial Doppler (TCD) velocities. PNR was retrospectively analysed against clinical parameters over 18 months. showed significant correlations Packed Volume (r=0.588, p=0.002), Mean...
Methamphetamine abuse continues to pose a significant public health concern globally, with numerous adverse effects on various body systems. is common drug of misuse in Nigeria. It derivative amphetamine, an enantiomer ephedrine potent addictive and majorly central nervous system (CNS) stimulating property. We present 30-year-old female history chronic methamphetamine who presented the emergency department Nnamdi Azikiwe University Teaching Hospital (NAUTH), Nnewi, symptoms consistent...
Background: Sickle cell anaemia (SCA) imposes a substantial healthcare burden, affecting millions of people worldwide. Understanding the determinants influencing SCA severity is crucial for enhanced disease management and optimized patient outcomes. This study aimed to investigate relationship between Neutrophil-Lymphocyte Ratio (NLR), Platelet-Neutrophil (PNR), Platelet-Lymphocyte (PLR), severity.
 Methods: A cohort 45 children diagnosed with undergoing treatment at Chukwuemeka...
Background: Maternal factors are determinants of birth outcome which includes weight, haematological indices and mode delivery their babies.Objectives: To determine the impact parity gestational age hypertensive mothers on some neonatal variables.Methods: A hospital based cross-sectional study measurement variables (birth red blood cells delivery) among controls was conducted over a period six months. Data were analyzed using Statistical Package for Social Sciences program (SPSS), version...
Background: Hemoglobin polymerization in sickle cell anemia (SCA) leads to abnormally rigid and adhesive erythrocytes that obstruct blood vessels, leading poor tissue perfusion, hence provoking inflammation damage of surrounding tissues. Adiponectin, a protein hormone, presumptively has anti-inflammatory characteristics, may be an important therapeutic target SCA. Aim: The aim the study was evaluate status adiponectin its correlation with disease severity Patients Methods: A total 84...
To determine the prevalence of venous thromboembolism (VTE) among adult sickle cell disease (SCD) patients in Nigeria.This was a multicentre retrospective study which medical records SCD were reviewed. Information on demographics, steady-state haemogram, clinical phenotypes, duration follow-up, history VTE including risk factors and management collected.Of 509 with median (IQR) follow-up 2 years, 10 (2.0%) had (9 DVT 1 PE). Their age 27 (22.8-30.3) years. Identifiable for included positive...
Aim: Granulocyte differentiation factor 15 (GDF15) is a growth and biomarker for many disorders where Ischaemia Reperfusion Injury (IRI) pathophysiologically relevant. Hence the need to evaluate GDF-15 as in Sickle Cell Disease (SCD).
 Study Design: This cross sectional study.
 Place Duration of Study: Department Haematology, Nnamdi University Teaching Hospital, Nnewi, Anambra state, Nigeria, between January December 2018.
 Methods: Ninety subjects were randomly recruited with...
Introduction: Sickle Cell Disease (SCD) is an inherited haemolytic disorder that affects virtually all body systems including the eye. Ocular complications of SCD could have dire consequences if not detected early.
 Objectives: We aimed at determining prevalence ocular in our patients.
 Methods: This study was carried out on patients attending both adult and Paediatric cell disease clinic Chukwuemeka Odumegwu Ojukwu Teaching Hospital, Akwa, Anambra State, Nigeria, over 8 month...
Background: Vaso-occlusive crisis (VOC) is a feature of sickle cell disease (SCD), an inherited medical condition which more common in Sub-Saharan Africa especially Nigeria and saddled with multi-systemic complications. Knowledge practice preventive measures VOC by patients may reduce the risk morbidity mortality. Aim: The purpose this manuscript to determine knowledge, attitude, various their relationship frequency painful crisis. Materials Methods: A cross-sectional descriptive survey was...