A5035358544- Mosquito-borne diseases and control
- Viral Infections and Outbreaks Research
- Malaria Research and Control
- Viral Infections and Vectors
- Travel-related health issues
- Influenza Virus Research Studies
- Vibrio bacteria research studies
- Migration, Identity, and Health
- Disaster Response and Management
- Cardiac Arrest and Resuscitation
- Healthcare Systems and Practices
- Global Maternal and Child Health
- Leptospirosis research and findings
- Mechanical Circulatory Support Devices
- Neurology and Historical Studies
- Zoonotic diseases and public health
- Aging, Elder Care, and Social Issues
- Hereditary Neurological Disorders
- African Botany and Ecology Studies
- Cardiac Structural Anomalies and Repair
- Global Public Health Policies and Epidemiology
- Poisoning and overdose treatments
- Global Health and Epidemiology
- Sepsis Diagnosis and Treatment
- Yersinia bacterium, plague, ectoparasites research
Centre Hospitalier Universitaire de La Réunion
2012-2022
Université de Bordeaux
2013-2021
Centre Hospitalier René-Dubos
2019
Hôpital de la Croix-Rousse
2016
Centre Hospitalier Saint-Denis
1997-2015
Hôpital Laveran
2015
Écologie Marine Tropicale des Océans Pacifique et Indien
2009-2014
Service de la Santé Publique
2010-2012
Intensive Care Society
2010
University of Milan
2003
Alphaviruses, including Chikungunya virus (CHIKV), produce a transient illness in humans, but severe forms leading to chronic incapacitating arthralgia/arthritis have been reported by mechanisms largely ill-characterized. The pathogenesis of CHIKV was addressed prospective cohort study 49 hospitalized patients from Reunion Island subsequently categorized into two distinct groups at 12 mo postinfection. Comprehensive analyses the clinical and immunological parameters throughout disease course...
Since 2003, the tropical arthritogenic chikungunya (CHIK) virus has become an increasingly medical and economic burden in affected areas as it can often result long-term disabilities. The clinical spectrum of post-CHIK (pCHIK) rheumatic disorders is wide. Evidence-based recommendations are needed to help physicians manage treatment afflicted patients.We conducted a 6-year case series retrospective study Reunion Island patients referred rheumatologist due continuous or musculoskeletal pains...
Abstract Mother-to-child transmission of chikungunya virus was reported during the 2005–2006 outbreak on Réunion Island, France. To determine effects this pregnancy outcomes, we conducted a study pregnant women in 2006. The population composed 1,400 (628 uninfected, 658 infected pregnancy, 27 before and 87 unknown dates). We compared outcomes for 655 + 27) not with who were pregnancy. Infection occurred first trimester 15% women, second 59%, third 26%. Only hospital admission differed...
Persistent disabilities are key manifestations of Chikungunya virus (CHIKV) infection, especially incapacitating polyarthralgia and fatigue. So far, little is known about their impact on health status. The present study aimed at describing the burden CHIKV prolonged or late-onset symptoms self-perceived La Réunion islanders. At 18 months after an outbreak virus, we implemented TELECHIK survey; a retrospective cohort conducted random sample representative SEROCHIK population-based survey. A...
This study was conducted to assess the impact of chikungunya on health costs during epidemic that occurred La Réunion in 2005-2006.From data collected from agencies, additional incurred by terms consultations, drug consumption and absence work were determined a comparison with expected outside period. The cost hospitalization estimated provided national database for short-term care considering all hospital stays which ICD-10 code A92.0 appeared. A cost-of-illness perspective third-party...
Long-lasting relapsing or lingering rheumatic musculoskeletal pain (RMSP) is the hallmark of Chikungunya virus (CHIKV) rheumatism (CHIK-R). Little known on their prognostic factors. The aim this study was to search determinants RMSP indicative CHIK-R. Three hundred and forty-six infected adults (age ≥ 15 years) having declared at disease onset were extracted from TELECHIK cohort study, Reunion island, analyzed using a multinomial logistic regression model. We also searched for predictors...
Abstract Mother-to-child transmission of chikungunya virus was reported during the 2005–2006 outbreak on Réunion Island, France. To determine effects this pregnancy outcomes, we conducted a study pregnant women in 2006. The population composed 1,400 (628 uninfected, 658 infected pregnancy, 27 before and 87 unknown dates). We compared outcomes for 655 + 27) not with who were pregnancy. Infection occurred first trimester 15% women, second 59%, third 26%. Only hospital admission differed...
Three different regimens were compared for treatment of falciparum malaria in displaced Kampucheans living encampments on the Thai-Kampuchean border 1983: single dose 750 mg mefloquine, 1.5 g sulfadoxine, 75 pyrimethamine (MSP); 600 quinine 8-hourly 3 days and 500 tetracycline 7 (Q3T7); or (Q7T7). Radical cure rates 98% (40/41) MSP, 76% (32/42) Q3T7 92% (33/36) Q7T7. The criterion failure was reappearance parasites by 35 after commencement no parasite clearance. Treatment failures comprised...
Leptospirosis causes reversible multiple organ failure, and its mortality remains high. The aim of this study was to determine the rate leptospirosis in an ICU offering all types support available nowadays compare it with bacterial sepsis.Retrospective, descriptive, single-center cohort study.The largest Reunion Island (Indian Ocean) a teaching hospital.Consecutive patients hospitalized for from January 2004 2015.None.We report 134 cases ICU. median age 40 years (interquartile range, 30-52...
Abstract Prolonged fatigue is increasingly reported among chikungunya virus (CHIKV)-infected populations. We investigated the relationships between CHIKV exposure, long-lasting rheumatic musculoskeletal pain (LRMSP) and chronic fatigue. 1094 participants (512 seropositive 582 seronegative) of TELECHIK population-based cohort were analysed considering duration manifestations throughout an average 2-year follow-up. Weighted prevalence rates ratios for LRMSP, idiopathic (ICF), syndrome...
Stress cardiomyopathy (SC) is a transient ventricular dysfunction rarely described in the critical care setting. To evaluate mechanisms, incidence, treatment and prognosis of SC. This retrospective observational study every critically-ill patient admitted to ICU over period two years. Among 1314 patients ICU, 20 (1.5%) were diagnosed with A total 249 experienced cardiogenic shock, whereas 8% suffering from SC was suspected because hemodynamic impairment (80% cases), ECG modifications (15%)...
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The purpose of the study was to weigh community burden chikungunya determinants on Reunion island. Risk factors were investigated within a subset 2101 adult persons from population-based cross-sectional serosurvey, using Poisson regression models for dichotomous outcomes. Design-based risk ratios and population attributable fractions (PAF) generated distinguishing individual contextual (i.e. that affect individuals collectively) determinants. disease twice (overall PAF value 89.5% vs....
Background: In Reunion Island, influenza is not considered a serious illness despite significant mortality in intensive care unit (ICU). We assess the post-pandemic of by comparing it to other community-acquired pneumonia our ICU.Methods: Retrospective, descriptive, and single-centre cohort study. The main aim was determine standardized ratio (SMR) for based on quartiles SAPSII score reference population 954 patients hospitalized pneumonia. Another analyze risk factors patients.Results: 127...