A5049570789- Lymphoma Diagnosis and Treatment
- Salivary Gland Tumors Diagnosis and Treatment
- RNA modifications and cancer
- Head and Neck Cancer Studies
- Cancer-related gene regulation
- Cancer-related molecular mechanisms research
- Mycobacterium research and diagnosis
- Cholangiocarcinoma and Gallbladder Cancer Studies
Kunming Medical University
2019-2021
Second People's Hospital of Yunnan Province
2005
Abstract Background This study was aimed to evaluate the involvement of lncRNA MALAT1 in modifying chemo‐sensitivity laryngeal squamous cell carcinoma (LSCC) lines. Methods Totally 108 pairs tumor tissues and matched para‐tumor normal were gathered from patients who pathologically confirmed as LSCC. Meanwhile, LSCC lines, including TU686, TU177, AMC‐HN‐8, LSC‐1, purchased their tolerance cisplatin, 5‐fluorouracil, paclitaxel, vincristine. Additionally, CCK‐8 assay, flow cytometry, transwell...
The characteristics of head and neck squamous cell carcinoma (HNSCC) across different anatomic sites in the Chinese population have not been studied. To determine genomic abnormalities underlying HNSCC sites, alterations selected cancer-related genes were evaluated.Genomic DNA samples obtained from formalin-fixed, paraffin-embedded tissues analyzed using targeted sequencing a panel 383 to alterations.A total 317 specimens collected, 2,156 protein-coding mutations, including 1,864 single...