Yanfei Guan

ORCID: 0000-0003-0471-9509
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About
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Research Areas
  • Sports injuries and prevention
  • Sports Performance and Training
  • Diabetes Management and Research
  • Ion channel regulation and function
  • Obesity, Physical Activity, Diet
  • Health and Lifestyle Studies
  • Lower Extremity Biomechanics and Pathologies
  • Neuroscience and Neural Engineering
  • Diet and metabolism studies
  • Memory and Neural Mechanisms
  • Stress Responses and Cortisol
  • Cardiovascular Effects of Exercise
  • Neuroscience and Neuropharmacology Research
  • Knee injuries and reconstruction techniques
  • Acute Myeloid Leukemia Research
  • Hematopoietic Stem Cell Transplantation
  • Musculoskeletal pain and rehabilitation
  • Sleep and related disorders
  • Chronic Myeloid Leukemia Treatments
  • Cardiac electrophysiology and arrhythmias
  • Immune cells in cancer
  • Exercise and Physiological Responses
  • Muscle activation and electromyography studies
  • Congenital Ear and Nasal Anomalies
  • NF-κB Signaling Pathways

Guangdong Medical College
2024

University of British Columbia
1987-2023

Yunnan University
2023

Kunming University of Science and Technology
2019-2022

First People's Hospital of Yunnan Province
2019-2022

Second Affiliated Hospital of Guangzhou Medical University
2019-2020

Guangzhou Medical University
2019-2020

Southern Medical University
2018-2020

Boai Hospital of Zhongshan
2018-2020

Wenzhou Medical University
2015

Abstract Background Type 1 diabetes mellitus (T1DM) is associated with an increased risk for cardiovascular disease (CVD) related morbidity and premature mortality. Regular physical activity plays important role in the primary secondary prevention of CVD, improving overall health wellbeing. Previous observational studies have examined associations between self-reported CVD factors largely adult Caucasian populations. However, limited work has evaluated relationship objectively measured other...

10.1186/s12933-021-01255-0 article EN cc-by Cardiovascular Diabetology 2021-03-12

Parkinson's disease (PD) is a common neurodegenerative disease, featured by motor deficits and non-motor symptoms such as cognitive impairment, malfunction of gamma-aminobutyric acid (GABA) mediated inhibitory transmission plays an important role in PD pathogenesis. The ginsenoside Rb1 molecule, major constituent the extract from Ginseng root, has been demonstrated to ameliorate prevent dopaminergic neuron death PD. However, whether can regulate GABAergic PD-associated its underlying...

10.18632/aging.102095 article EN cc-by Aging 2019-07-17

Inter-limb asymmetry above a certain threshold in functional performance indicates increased injury risk sports. Fatigue has been found to increase bilateral lower-limb jumping among high-school and adult athletes, whereas this impact not examined child athletes. This study aimed examine the effect of fatigue on inter-limb performances elite Taekwondo athletes aged between 9 11 years. Performance single-leg jumps, Star Excursion Balance Test (SEBT), muscle (hamstring gastrocnemius)...

10.1186/s13018-020-02175-7 article EN cc-by Journal of Orthopaedic Surgery and Research 2021-01-09

Abstract For fencing, speed of the lunge is considered critical to success. The aim this study investigate determinants based on biomechanics. Ground reaction force (GRF) and three‐dimensional kinematic data were collected from 7 elite fencers 12 intermediate‐level performing maximum‐effort lunges. results showed that acquired a higher horizontal peak velocity centre gravity (HPV) concomitantly GRF exerted by rear leg (PGRF) than ( P < .01). Studying affecting factors, obtained joint...

10.1080/17461391.2017.1414886 article EN European Journal of Sport Science 2017-12-17

Abstract Background This study was aimed to evaluate the involvement of lncRNA MALAT1 in modifying chemo‐sensitivity laryngeal squamous cell carcinoma (LSCC) lines. Methods Totally 108 pairs tumor tissues and matched para‐tumor normal were gathered from patients who pathologically confirmed as LSCC. Meanwhile, LSCC lines, including TU686, TU177, AMC‐HN‐8, LSC‐1, purchased their tolerance cisplatin, 5‐fluorouracil, paclitaxel, vincristine. Additionally, CCK‐8 assay, flow cytometry, transwell...

10.1002/jcla.23116 article EN cc-by Journal of Clinical Laboratory Analysis 2019-12-14

The action of cadmium ions on transmitter release was studied at the neuromuscular junction in mouse diaphragm. In presence raised K + , Cd 2+ caused a parallel shift to right graph rate (frequency miniature end-plate potentials, fmepp) versus log [Ca ], with no change maximum or slope, indicating competitive mode . apparent dissociation constant for 3 μM. calcium-free solutions containing 15 mM rise fmepp, which subsequently slowly declined despite continued fmepp by could be interrupted,...

10.1139/y87-334 article EN Canadian Journal of Physiology and Pharmacology 1987-10-01

The impact of interlimb asymmetries on sport injuries is unclear because inconsistent findings, and there a lack research youth athletes the taekwondo.To examine effects functional noncontact lower limb in athletes.Cohort study; Level evidence, 2.A total 415 taekwondo (318 boys 97 girls) aged 6 to 17 years underwent baseline testing determine through single-leg countermovement jump (CMJ), hop, triple hop tests as well Star Excursion Balance Test. were then evaluated for 12 months observe...

10.1177/23259671231185586 article EN cc-by-nc-nd Orthopaedic Journal of Sports Medicine 2023-08-01

ABSTRACT Bilateral asymmetry in lower‐limb power and dynamic balance has been associated with increased risk of sport injury, whereas there is a lack research examining this for child athletes. Twenty‐eight fencers (19 boys 9 girls, aged 9.71 ± 1.08 years) 28 Taekwondo athletes were examined on the single‐leg jump Star Excursion Balance Test (SEBT) performance. A mixed model design ANOVA (2 [Sex: Boys, Girls] × 2 [Sport group: Fencing, Taekwondo] [Limb: Dominant, Non‐dominant Leg]) was...

10.1080/17461391.2020.1814425 article EN European Journal of Sport Science 2020-08-23

Background: Risk factors for non-contact lower-limb injury in pediatric-age athletes and the effects of lateral dominance sport (laterally vs. non-laterally dominant sports) on have not been investigated. Purpose: To identify risk athletes. Methods: Parents and/or legal guardians 2269 aged between 6–17 years were recruited. Each participant completed an online questionnaire that contained 10 questions about athlete’s training preceding 12 months. Results: The multivariate logistic regression...

10.3390/jcm10143171 article EN Journal of Clinical Medicine 2021-07-19

10.1007/bf00586518 article EN Pflügers Archiv - European Journal of Physiology 1987-11-01

To explore whether there was an increased secretion of cystatin C (Cys C) in twin pregnancy.Patients with a total 281 singleton pregnancies (including 38 patients preeclampsia) and 72 pregnancies, as well 42 who were not pregnant, included this study. We tested levels serum Cys C, creatinine, uric acid, along the estimated glomerular filtration rate (eGFR), different groups.The all 3 trimesters for women pregnancy much higher than those corresponding pregnancy. However, we observed little...

10.1093/labmed/lmy059 article EN Laboratory Medicine 2018-08-22

Fear extinction remains an unresolved challenge for behavioral exposure therapy in patients with post-traumatic stress disorder. Previous reports have suggested that social support from either familiar or unfamiliar same-sex partners is beneficial to attenuating fear response during and renewal. Despite that, few studies examined the effects of advance on and/or retrieval. It also not clear whether company by a receptive mating partner facilitates extinction. In present study, we address...

10.3389/fnins.2020.00062 article EN cc-by Frontiers in Neuroscience 2020-02-07

<b>Objective:</b> Hemoglobin A<sub>1c</sub> (HbA<sub>1c</sub>) concentrations reflect glycemic control and diabetic complications. However, there is little evidence supporting the pathological role of HbA<sub>1c</sub> in development progression We investigated impact on endothelial cell function potential mechanisms. <b>Methods:</b> The effects viability migration human umbilical vein cells (HUVECs) were measured by Cell Counting Kit-8 a wound healing scratch assay, respectively. Production...

10.1055/s-0035-1554622 article EN Experimental and Clinical Endocrinology & Diabetes 2015-06-11

Background: The cause of sudden sensorineural hearing loss (SSNHL) is still unknown. Literature has indicated that there a statistically significant correlation between hyperhomocysteinemia and SSNHL, yet lack study in the relationship concerning total frequency deafness subtype SSNHL. This investigated plasma concentration homocysteine (Hcy), serum folic acid occurrence treatment responding adult patients, explored whether targeted early intervention was associated with improved clinical...

10.21037/apm.2019.10.08 article EN cc-by-nc-nd Annals of Palliative Medicine 2019-11-01

Abstract Background: Inter-limb asymmetry above a certain threshold in functional performance indicates increased injury risk sports. Fatigue has been found to increase bilateral lower-limb jumping among high-school and adult athletes, whereas this impact not examined for child athletes. Methods: Performance of single-leg jumps, Star Excursion Balance Test (SEBT), muscle (hamstring gastrocnemius) flexibility were measured 13 elite male Taekwondo athletes (aged 9.85 ± 0.80 years) at both the...

10.21203/rs.3.rs-90419/v1 preprint EN cc-by Research Square (Research Square) 2020-10-13

Adolescents living with type 1 diabetes (T1D) have an increased risk of developing cardiovascular disease. Sleep patterns physiological and behavioral impacts on outcomes. This study aimed to investigate the associations between sleep CVD factors in adolescents T1D their peers without T1D. cross-sectional assessed characteristics (and associations) adolescents, aged 12-18 years, (

10.3390/jcm11185295 article EN Journal of Clinical Medicine 2022-09-08
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