A5101631312- Maternal and Perinatal Health Interventions
- Maternal and fetal healthcare
- Advanced biosensing and bioanalysis techniques
- Pregnancy and preeclampsia studies
- Extracellular vesicles in disease
- Birth, Development, and Health
- Assisted Reproductive Technology and Twin Pregnancy
- Iron Metabolism and Disorders
- Ectopic Pregnancy Diagnosis and Management
- MicroRNA in disease regulation
- Biosensors and Analytical Detection
- Prenatal Screening and Diagnostics
- Prostate Cancer Diagnosis and Treatment
- Kidney Stones and Urolithiasis Treatments
- Urological Disorders and Treatments
- Hemoglobinopathies and Related Disorders
- Cancer, Lipids, and Metabolism
- Esophageal Cancer Research and Treatment
- Acute Ischemic Stroke Management
- Ovarian function and disorders
- Endometrial and Cervical Cancer Treatments
- RNA Interference and Gene Delivery
- Urologic and reproductive health conditions
- Gastric Cancer Management and Outcomes
- Uterine Myomas and Treatments
Queen Mary University of London
2018-2025
Southern Medical University
2017-2024
Zhejiang Chinese Medical University
2024
Nanfang Hospital
2003-2024
Foshan Maternity and Child Health Care Hospital
2016-2023
First Affiliated Hospital of Xi'an Jiaotong University
2023
Guangdong General Hospital
2023
Sichuan University
2018-2022
Sichuan Research Center of New Materials
2022
First Affiliated Hospital of Wenzhou Medical University
2021
// Dazhi Fan 1, 2 , Shuzhen Wu Li Liu 3, 5 Qing Xia 6 Guo Tian Wen Wang Shaoxin Ye Lijuan Jiaming Rao 7 Xiao Yang 8 Zhen Yu 9 Lihong Xin 10 Song 11 Zhenghua Duan 12 Tianchen Zhang 13 4 Xiaoling and Zhengping 1 Foshan Institute of Fetal Medicine, Southern Medical University Affiliated Maternal Child Health Hospital Foshan, Guangdong, 528000, China Department Obstetrics, 3 Epidemiology Biostatistics, School Public Health, Anhui University, Hefei, Anhui, 230032, Integrated Traditional Western...
Abstract Bacterial extracellular vesicles (BEVs) are nanoscale secreted by bacteria. They possess lipid bilayer membranes and contain multiple periplasmic cytoplasmic components, facilitating their intercellular communications through transferring of various bioactive molecules. Considering intrinsic structure, delivery capacity, immunogenic property, facile production, versatile modification, more studies have exploited BEVs directly as therapeutic agents or engineered vehicles for the...
Abstract Background The current evidence about anemia and iron deficiency (IDA) during pregnancy remains elusive in China. purpose of this study is to investigate the prevalence IDA their risk factors Chinese pregnant women. Methods A nationwide cross-sectional survey women was conducted antenatal visits. Using a multi-stage sampling method, 24 hospitals from 16 provinces across China were selected. Structured questionnaires administered collect information participants extract clinical data...
Abstract Small extracellular–vesicule-associated microRNA (sEV-miRNA) is an important biomarker for cancer diagnosis. However, rapid and sensitive detection of low-abundance sEV-miRNA in clinical samples challenging. Herein, a simple electrochemical biosensor that uses DNA nanowire to localize catalytic hairpin assembly (CHA), also called domino-type localized (DT-LCHA), has been proposed sEV-miRNA1246 detection. The DT-LCHA offers triple amplification, (i). CHA system was nanowire, which...
Abstract Background Breast cancer‐related lymphedema (BCRL) is one of the common postoperative complications that severely affects functions arm and quality life. Since difficult to treat prone recurrence, early prevention crucial. Methods Patient diagnosed with breast cancer ( N = 108) were randomized intervention n 52) or control group 56). In group, patients provided program based on theory knowledge–attitude–practice during perioperative period first three chemotherapy sessions (mainly...
Abstract The capacity to identify small amounts of pathogens in real samples is extremely useful. Herein, we proposed a sensitive platform for detecting using cyclic DNA nanostructure@AuNP tags (CDNA) and cascade primer exchange reaction (cPER). This employs wheat germ agglutinin-modified Fe 3 O 4 @Au magnetic nanoparticles (WMRs) bind the E. coli O157:H7, then triggers cPER generate branched products CDNA tag hybridization with high stability amplified SERS signals. It can target as low...
Uterine niche is defined as a triangular anechoic structure at the site of scar or gap in myometrium previous caesarean section. The main clinical manifestations are postmenstrual spotting and intrauterine infection, which may seriously affect daily life nonpregnant women. Trials have shown an excellent safety efficacy for potential mesenchymal stem cells (MSCs) therapeutic option reconstruction. Therefore, this study designed to investigate using MSCs treatment uterine niche.This phase II...
Abstract The profiling of small extracellular vesicle-associated microRNAs (sEV-miRNAs) plays a vital role in cancer diagnosis and monitoring. However, detecting sEV-miRNAs with low expression clinical samples remains challenging. Herein, we propose novel electrochemical biosensor using localized DNA tetrahedron-assisted catalytic hairpin assembly (LDT-CHA) for sEV-miRNA determination. LDT-CHA contained tetrahedrons CHA substrates, leveraging an efficient reaction to enable sensitive rapid...
Extracellular vesicles (EVs) have been identified as cell-cell communication agents, and EVs derived from mesenchymal stem cells (MSCs) exhibit therapeutic effects similar to those of the origin. Precipitation methods used extensively for EV harvests, such UC- (ultracentrifugation-) or PEG- (polyethylene glycol-) based methods, difference in MSCs by UC PEG is not fully understood. We harvested amniotic fluid (AF-MSCs) PEG-based precipitation conducted a comparison study two methods: output,...