A5038852805- Obesity, Physical Activity, Diet
- Nutritional Studies and Diet
- Consumer Attitudes and Food Labeling
- COVID-19 and Mental Health
- Physical Activity and Health
- Psychological Well-being and Life Satisfaction
- COVID-19 Pandemic Impacts
- Digital Mental Health Interventions
- Health disparities and outcomes
- Mobile Health and mHealth Applications
- Organizational Change and Leadership
- Viral Infections and Outbreaks Research
- Plant Virus Research Studies
- SARS-CoV-2 and COVID-19 Research
- Food Waste Reduction and Sustainability
- RNA and protein synthesis mechanisms
- Nutrition, Genetics, and Disease
- Viral Infectious Diseases and Gene Expression in Insects
- Telemedicine and Telehealth Implementation
- Animal Virus Infections Studies
University College London
2021-2025
Public Health England
2021-2022
Department of Health and Social Care
2022
Office for Health Improvement and Disparities
2021
Healthcare Quality Improvement Partnership
2021
Abstract Purpose of Review Obesity is a growing global healthcare concern. A proposed driver the recent increase in ultra-processed food (UPF) intake. However, disagreement surrounds concept UPF, strength evidence, and suggested mechanisms. Therefore, this review aimed to critically appraise evidence on UPF obesity. Recent Findings Observational studies demonstrate positive associations between intake, weight gain, overweight/obesity, more clearly adults than children/adolescents. This...
Abstract UK front of package labelling (FOPL) informs consumers on the nutrient content food. However, FOPL does not consider food processing, and with government being urged to act ultra-processed (UPF), whether UPF should be added is unclear. This study compared drink in National Diet Nutrition Survey (NDNS) Intake24 database based FOPL, NOVA classification, understand are covered by dietary recommendations for foods high fat, salt sugar. NDNS items were coded into minimally processed...
The recent emergence of SARS-CoV-2 variants with increased transmission, pathogenesis and immune resistance has jeopardised the global response to COVID-19 pandemic. Determining fundamental biology viral understanding their evolutionary trajectories will guide current mitigation measures, future genetic surveillance vaccination strategies. Here we examine virus entry by B.1.1.7 lineage, commonly referred as UK/Kent variant. Pseudovirus infection model cell lines demonstrate that is enhanced...
The emergence of SARS-CoV-2 variants has exacerbated the COVID-19 global health crisis. Thus far, all carry mutations in spike glycoprotein, which is a critical determinant viral transmission being responsible for attachment, receptor engagement and membrane fusion, an important target immunity. Variants frequently bear truncations flexible loops N-terminal domain (NTD) spike; functional importance these modifications remained poorly characterised. We demonstrate that NTD deletions are...
COVID-19-related restrictions impacted weight and weight-related factors during the initial months of pandemic. However, longitudinal analyses are scarce. An online, study was conducted among self-selected UK adults (n = 1818), involving three surveys (May-June, August-September, November-December 2020), covering anthropometric, sociodemographic, behavioural measures. Data were analysed using generalised estimating equations. Self-reported average weight/body mass index (BMI) significantly...
Abstract Increased ultra-processed food (UPF) intake is associated with adverse health outcomes. However, limitations in UPF evidence, and partial overlap between UK front of package labelling (FOPL) degree processing, the value processing within dietary guidance unclear. This study compared drink from National Diet Nutrition Survey (NDNS) database based on micronutrient content, Nova classification FOPL. The aim was to examine contributions government recommendations for adult females...
COVID-19 pandemic restrictions impacted dietary habits during the initial months of pandemic, but long-term effects are unclear. In this longitudinal study, self-selected UK adults ( n = 1,733, 71.1% female, 95.7% white ethnicity) completed three online surveys (May–June, August–September, and November–December 2020, with a retrospective pre-pandemic component in baseline survey), self-reporting sociodemographics, lifestyle, behaviours, including high fat, salt, sugar (HFSS) snacks, HFSS...
Physical inactivity is a leading risk factor for many health conditions, including cardiovascular disease, diabetes, and cancer; therefore, increasing physical activity (PA) public priority. Health care professionals (HCPs) in primary are pivotal addressing inactivity; however, few HCPs provide PA advice to patients. There can be obstacles delivering advice, lack of time, confidence, or knowledge. Digital technology has the potential overcome facilitate advice. However, it unknown if how...
Introduction Obesity increases the risk of morbidity and mortality. A major driver has been increased availability ultra-processed food (UPF), now main UK dietary energy source. The Eatwell Guide (EWG) provides public guidance for a healthy balanced diet but offers no UPF guidance. Whether can largely consist UPFs is unclear. No study assessed whether health impact adhering to guidelines depends on processing. Furthermore, our will assess 6-month behavioural support programme aimed at...
Abstract Objective To compare food and drink in the UK National Diet Nutrition Survey (NDNS) database based on their front of package label multiple traffic light (FOPL MTL) score, nutrient content NOVA classification. Design cross-sectional profiling analysis. Setting The supply. Food items were obtained from Intake24, electronic dietary assessment method used NDNS Year 12 (2019–20). Main outcome measures Nutrient content, FOPL MTL classification each item. Items coded into minimally...
Background The COVID-19 pandemic has seen repeated government enforced restrictions on movement. This study aimed to evaluate longitudinal trends in physical activity (PA) a self-selected UK-based sample and identify the key correlates of these trends. Methods From 23 April 2020 30 January 2021, measures PA engagement were collected 1,947 adults. Generalised estimating equations (GEE) explored over time, how sociodemographic, health contextual factors impacted participant’s attainment World...
The COVID-19 pandemic has negatively impacted people living with obesity. aim was to examine the continued impact of on mental health obesity and associations food insecurity, loneliness health-related behaviours.The study recruited 1187 UK adults who completed an online survey, which examined behaviours from July 2020 (end first lockdown in United Kingdom) point they survey 2021. Regression analyses were used relationships between outcome variables demographic factors, hierarchical linear...
Abstract Background COVID-19-related restrictions impacted weight and weight-related factors during the initial months of pandemic. However, longitudinal analyses are scarce. Methods An online, study was conducted among self-selected UK adults (n=1,818), involving three surveys 2020 (May-June, August-September, November-December), covering height, sociodemographic, behavioural measures. Data were analysed using generalised estimating equations. Results Self-reported average body mass index...
Abstract COVID-19 pandemic restrictions impacted dietary habits during the initial months of pandemic, but long-term effects are unclear. In this longitudinal study, self-selected UK adults (n=1,733) completed three online surveys (May-June, August-September and November-December 2020, with a retrospective pre-pandemic component in baseline survey), self-reporting sociodemographics, lifestyle behaviours, including high fat, salt sugar (HFSS) snacks, HFSS meals fruit vegetable (FV) intake....
Abstract Background The COVID-19 pandemic has seen government enforced restrictions on movement, with ‘stay-at-home’ orders in place for a second and third time many nations. Such have altered physical activity (PA) habits. This study aimed to evaluate longitudinal trends PA self-selected UK-based sample the key predictors of these trends. Methods From 23 April 2020 30 January 2021, an online survey collected detailed measures engagement 1,947 adults. Generalised estimating equations (GEE)...
Background: Physical inactivity is a leading risk factor for many health conditions, including cardiovascular disease, diabetes and cancer; increasing physical activity (PA) therefore public priority. Healthcare professionals (HCPs) in primary care have been identified as being pivotal addressing inactivity, yet few HCPs provide PA advice to patients. There can be obstacles delivering advice, lack of time, confidence or knowledge. Digital technology has the potential overcome facilitate...