A5026489856- Wound Healing and Treatments
- Skin Protection and Aging
- Pressure Ulcer Prevention and Management
- Dermatology and Skin Diseases
- Psoriasis: Treatment and Pathogenesis
- Planarian Biology and Electrostimulation
- Bee Products Chemical Analysis
- Antioxidant Activity and Oxidative Stress
- Genomics, phytochemicals, and oxidative stress
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Burn Injury Management and Outcomes
- Heme Oxygenase-1 and Carbon Monoxide
- Tendon Structure and Treatment
- AI in cancer detection
- Circadian rhythm and melatonin
- Air Quality and Health Impacts
- Medical and Biological Ozone Research
- melanin and skin pigmentation
- Hydrogen's biological and therapeutic effects
- Anatomy and Medical Technology
- Laser Applications in Dentistry and Medicine
- Diabetic Foot Ulcer Assessment and Management
- Essential Oils and Antimicrobial Activity
- Digital Imaging for Blood Diseases
- Exercise and Physiological Responses
Universidade do Estado do Rio de Janeiro
2016-2025
Universidade Federal de Minas Gerais
2024
Universidade Estadual de Campinas (UNICAMP)
2023
In-Q-Tel
2014
Universidade Federal Rural do Rio de Janeiro
2011-2013
Universidade Federal do Rio de Janeiro
2011-2013
Inserm
2005
Abstract Grasslands are the largest contributor of nitrous oxide (N 2 O) emissions in agriculture sector due to livestock excreta and nitrogen fertilizers applied soil. Nitrification inhibitors (NIs) added N input have reduced O emissions, but can show a range efficiencies depending on climate, soil, management conditions. A meta-analysis study was conducted investigate factors that influence efficiency NIs fertilizer reducing focused grazing systems. Data from peer-reviewed studies...
Stress impairs wound healing of cutaneous lesions; however, the mechanism is still unclear. The aim this study was to evaluate effects rotational stress on in mice and propose a mechanism. Male were spun at 45 rpm for 15 min every hour beginning 3 days before wounding until euthanasia. Control animals not subjected stress. To confirm that catecholamines participate stress-induced delay healing, treated daily with propranolol. An excisional lesion created measured. Seven 14 later, killed...
Abstract Supplementation with olive and fish oils reverses the effects of stress on behavioral activities adrenal activation. However, previous studies have not shown whether supplementation oil could inhibit cutaneous wound healing. Thus, this study investigated or healing in stressed mice. Mice were subjected to rotational treated daily until euthanasia. An excisional lesion was created each mouse, 14 days later, lesions analyzed. In addition, murine skin fibroblasts exposed elevated...
Sympathetic nerve failure has been proposed as a contributing factor in impaired cutaneous wound healing diabetes mellitus. Nevertheless, no studies have shown whether beta-adrenoceptor blockade through beta-blocker (e.g., propranolol) administration may alter of diabetic lesions. This study evaluated macro- and microscopically the effects propranolol on streptozotocin-induced rats. Acute was induced by single intraperitoneal injection streptozotocin 14 days before wounding. Animals were...
Stress impairs cutaneous wound healing; however, it is unclear how beta-adrenoceptors participates in alterations induced by stress on skin repair. Therefore, the aim of this study was to investigate effects propranolol, a non-selective beta-blocker, administration healing chronically stressed mice. Male mice were spun at 115 rpm for 15 min every hour from three days before wounding until euthanasia. Control animals not submitted stress. Stressed and control treated with propranolol...
Eucalyptol is a monoterpenoid oil present in many plants, principally the Eucalyptus species, and has been reported to have anti-inflammatory antioxidative effects.Since potential effect of eucalyptol on mouse lung repair not yet studied, considering that chronic obstructive pulmonary disease (COPD) fourth leading cause death worldwide, aim this study was investigate treatment emphysematous mice.Male mice (C57BL/6) were divided into following groups: control (sham-exposed), cigarette smoke...
Extra virgin olive oil (EVOO) has proved beneficial effects in skin wound healing of chronic lesions; however, the EVOO acute wounds are not completely understood. This study investigated short-term and long-term administration a diet rich on healing. To check this, mice were fed with for 1 week (short term), month, or 3 months (long term). The control group received standard diet. Mouse macrophages treated vitro hydroxytyrosol (HT), which is main polyphenol. Short-term an vivo increased...
1 The participation of sympathetic efferent fibres in wound healing is not well understood. aim the present study was to investigate effects b1- and b2-adrenoceptor blockade on rat excisional cutaneous healing. 2 Male rats were treated orally with propranolol dissolved drinking water (50 mg/kg per day), whereas control group received without propranolol. Propranolol administered daily until killed. A full-thickness lesion performed. area measured evaluate contraction. After had been killed,...
Severe burns stimulate a hypermetabolic response that causes systemic complications. Propranolol, nonselective beta-blocker, reduces this and increases survival. Nevertheless, few studies have shown the effects of propranolol on healing severe burns. This study evaluated macroscopically microscopically administration (low-dose) cutaneous wound burn-injured rats.A third-degree burn (10 percent total body surface area) was created in female Wistar rats. Beginning 1 week after burning, animals...
Abstract: Stress-induced catecholamine impairs the formation of granulation tissue acting directly in fibroblast activity; however, mechanism by which high levels catecholamines alter is still unclear. Thus, aim this study was to investigate how epinephrine compromise activity murine dermal fibroblasts. Dermal fibroblasts isolated from skin neonatal Swiss mice were preincubated with α- or β-adrenoceptor antagonists. Thereafter, cells exposed physiologically elevated plus antagonists, and...
Stress prolongs the inflammatory response compromising dermal reconstruction and wound closure. Acute stress-induced inflammation increases indoleamine 2, 3-dioxygenase-stimulated tryptophan catabolism. To investigate role of 3-dioxygenase expression administration in adverse effects stress on cutaneous healing, mice were submitted to chronic restraint treated with daily until euthanasia. Excisional lesions created each mouse 5 or 7 days later, analyzed. In addition, murine skin fibroblasts...
Participation of the peripheral nervous system in wound healing is not well understood. The aim this study was to investigate effects sympathetic denervation on rat excisional cutaneous healing. Male rats were chemically denervated with intraperitoneal administration 6‐hydroxydopamine (6‐OHDA) 1% ascorbic acid. 6‐OHDA or vehicle administered twice a week until euthanasia, beginning 7 days before wounding. A full‐thickness lesion performed and area measured evaluate contraction. After...
It has been clinically and experimentally shown that cigarette smokers suffer from impaired wound healing, but the mechanisms lead to alterations are not well understood. The aim of this study was investigate if effects smoke exposure on excisional cutaneous healing different depending strain (Swiss, BALB/c C57BL/6 mice) studied. Male mice were exposed nine whole cigarettes per day, 3 times/day, daily, for 10 days. In 11th day a full-thickness performed. Control group sham-exposed also had...