Yonghe Hu

ORCID: 0000-0001-5666-8577
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About
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Research Areas
  • High Altitude and Hypoxia
  • Mangiferin and Mango Extracts
  • Disaster Response and Management
  • Cancer-related molecular mechanisms research
  • Airway Management and Intubation Techniques
  • Heme Oxygenase-1 and Carbon Monoxide
  • Retinal Diseases and Treatments
  • Advanced Glycation End Products research
  • Protein Degradation and Inhibitors
  • Immune Cell Function and Interaction
  • Advanced Sensor and Energy Harvesting Materials
  • Cardiac Ischemia and Reperfusion
  • Traditional Chinese Medicine Analysis
  • Epigenetics and DNA Methylation
  • RNA modifications and cancer
  • Viral gastroenteritis research and epidemiology
  • Obstructive Sleep Apnea Research
  • Bioinformatics and Genomic Networks
  • NF-κB Signaling Pathways
  • Lung Cancer Diagnosis and Treatment
  • Cardiovascular Function and Risk Factors
  • Medicinal Plants and Bioactive Compounds
  • Inflammasome and immune disorders
  • Neuroscience of respiration and sleep
  • Monoclonal and Polyclonal Antibodies Research

Southwest Jiaotong University
2017-2025

Huzhou Central Hospital
2022-2024

Zhejiang Chinese Medical University
2024

Huzhou University
2022-2024

Zhejiang University
2022-2024

Meizhou City People's Hospital
2024

Chengdu University
2021-2023

Chengdu Military General Hospital
2012-2023

Chengdu University of Traditional Chinese Medicine
2023

Chengdu Medical College
2021

The naturally microstructure-bioinspired piezoresistive sensor for human–machine interaction and human health monitoring represents an attractive opportunity wearable bioelectronics. However, due to the trade-off between sensitivity linear detection range, obtaining sensors with both a wide pressure range high is still great challenge. Herein, we design hierarchically flexible consisting of hierarchical polyaniline/polyvinylidene fluoride nanofiber (HPPNF) film sandwiched two interlocking...

10.1021/acsnano.1c01606 article EN ACS Nano 2021-06-15

Background/Aims: It is well documented that hyperglycemia-induced oxidative stress an important causative factor of endothelial dysfunction. Cinnamaldehyde (CA) a key flavor compound in cinnamon essential oil can enhance the antioxidant defense against reactive oxygen species (ROS) by activating NF-E2-related 2 (Nrf2), which has been shown to have cardiovascular protective effect, but its role dysfunction induced high glucose unknown. Methods: Dissected male C57BL/6J mouse aortic rings and...

10.1159/000374074 article EN cc-by-nc Cellular Physiology and Biochemistry 2015-01-01

Given the importance of aggregation advanced glycation end products (AGEs) and cardiac inflammation in onset progression diabetic cardiomyopathy (DCM), our objective this study was to demonstrate cardioprotective effect mangiferin, an antidiabetic anti-inflammatory agent, on rat model. The DCM model established by a high-fat diet low dose streptozotocin. rats were treated orally with mangiferin (20 mg/kg) for 16 weeks. Serum left ventricular myocardium collected determination inflammatory...

10.1139/cjpp-2015-0073 article EN Canadian Journal of Physiology and Pharmacology 2015-11-03

Abstract With the development of modern medicine, importance continuous and reliable pulse wave monitoring has increased significantly in physiological evaluation disease diagnosis. Among them, 3D reconstruction is indispensable, needs rely on ultra‐high resolution sensor arrays, that is, high spatial resolution, temporal force resolution. Herein, a flexible high‐density 32 × tactile array based pressure‐sensitive tunneling mechanism develpoed. Conformal graphene nanowalls ( GNWs ) pattern...

10.1002/adfm.202406022 article EN Advanced Functional Materials 2024-06-10

After receiving the 25 April 2015 Nepal earthquake relief mission, a fully self-sufficient Rescue Center of Trauma set up quickly in downtown Kathmandu by Chengdu Military Medical Team PLA P. R. China.The medical team consisted 68 members and 40 tons supplies, which was equivalent to small hospital. The area living were constructed with tents. Operating areas converted from eight simple bungalows. main purpose save those survivors who needed surgery.From 30 10 May, 35 cases orthopaedic...

10.1007/s00264-016-3284-2 article EN cc-by International Orthopaedics 2016-09-02

BackgroundApproximately one-third of patients who undergo double-lumen tube (DLT) intubation in the conventional supine position experience DLT malposition. No randomized study investigates effect lateral position. We therefore aimed to evaluate on placement a compared intubation, and test primary hypothesis that could reduce incidence malposition.MethodsWe randomly allocated 108 undergoing video-assisted thoracic surgery receive comfortable surgically required (lateral group) or (supine...

10.1016/j.eclinm.2023.102402 article EN cc-by-nc-nd EClinicalMedicine 2024-01-01

Abstract Bone-related diseases pose a major challenge in contemporary society, with significant implications for both health and economy. Copper, vital trace metal the human body, facilitates wide range of physiological processes by being crucial function proteins enzymes. Numerous studies have validated copper's role bone regeneration protection, particularly development expansion collagen. Owing to numerous biological advantages, an increasing number scientists are endeavoring fabricate...

10.1093/rb/rbaf014 article EN cc-by Regenerative Biomaterials 2025-03-18

Diabetic cardiomyopathy (DCM) is one of the most common complications diabetes without effective treatment options. Its pathogenesis complex and remains unclear. Long non-coding RNA (lncRNA) MIAT allele has been reported to be enriched in DCM patients activate a pyroptosis program hypoxia-induced H9c2 cells. Thus, whether played role clarified. In study, expression was found elevated serum diabetic patients, as well high-glucose induced cardiomyocytes mice. Further, levels CASP1 correlation...

10.1016/j.isci.2021.103518 article EN cc-by-nc-nd iScience 2021-11-26

In recent years novel human respiratory disease agents have been described for Southeast Asia and Australia. The causative pathogens were classified as pteropine orthoreoviruses with a strong phylogenetic relationship to of bat origin.In this report, we isolated Melaka-like reovirus (named "Cangyuan virus") from intestinal content samples one fruit residing in China's Yunnan province. Phylogenetic analysis the whole Cangyuan virus genome sequences segments L, M S demonstrated genetic...

10.1186/s12866-014-0293-4 article EN cc-by BMC Microbiology 2014-11-29

The purpose of this study was to investigate the cardioprotective effect mangiferin on diabetic cardiomyopathy (DCM). DCM model induced by a high-fat diet and low dose streptozotocin. We evaluated characteristics serial echocardiography, electron microscopy, histopathologic analysis cardiomyocyte fibrosis area, Western blot matrix metalloproteinase-2 (MMP-2) MMP-9 expression. Rats with showed severe left ventricular dysfunction cardiac fibrosis. Mangiferin mitigated prevented accumulation...

10.1139/cjpp-2013-0090 article EN Canadian Journal of Physiology and Pharmacology 2013-05-08

Colorectal cancer (CRC) is the third most diagnosed worldwide. Progesterone associated with a decreased risk of CRC and leads to favourable prognosis. However, specific mechanism by which progesterone suppresses malignant progression remains be elucidated. In present study, level was first analysed in 77 patients CRC, immunohistochemistry performed detect expression receptor (PGR) paired specimens. The correlations between progesterone, PGR prognosis were assessed. A Cell Counting Kit‑8...

10.3892/or.2021.8046 article EN cc-by-nc-nd Oncology Reports 2021-04-09

Mangiferin functions as a perfect anti-oxidative compound in the diabetic heart, however, exact mechanism remains to be elucidated. Here, we show cardioprotective effect of mangiferin under high glucose-induced cardiotoxic condition mainly contributed enhanced autophagy via suppressing mTORC1 downstream signal transduction. Primary neonatal rat cardiomyocytes were cultured detect myocytes injury, autophagy, and related transduction different doses glucose treatment. High (30 mM) reduced...

10.3389/fphar.2018.00383 article EN cc-by Frontiers in Pharmacology 2018-04-17
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