Jia-Li Liang

ORCID: 0000-0002-2800-7349
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Research Areas
  • Congenital Heart Disease Studies
  • Ginger and Zingiberaceae research
  • Natural product bioactivities and synthesis
  • Genomics, phytochemicals, and oxidative stress
  • Aortic Disease and Treatment Approaches
  • Phytochemicals and Antioxidant Activities
  • Cardiac and Coronary Surgery Techniques
  • Aortic aneurysm repair treatments
  • NF-κB Signaling Pathways
  • Inflammatory mediators and NSAID effects
  • Plant biochemistry and biosynthesis
  • Coronary Artery Anomalies
  • Phytochemistry and Bioactive Compounds
  • Pulmonary Hypertension Research and Treatments
  • Cardiac Structural Anomalies and Repair
  • Essential Oils and Antimicrobial Activity
  • Additive Manufacturing and 3D Printing Technologies
  • Fluid Dynamics and Heat Transfer
  • Biological and pharmacological studies of plants
  • Polysaccharides and Plant Cell Walls
  • Retinoids in leukemia and cellular processes
  • Fetal and Pediatric Neurological Disorders
  • Mangiferin and Mango Extracts
  • Tannin, Tannase and Anticancer Activities
  • Ginseng Biological Effects and Applications

Guangzhou University
2023-2024

First Affiliated Hospital of GuangXi Medical University
2024

Guangxi Medical University
2024

Guangzhou University of Chinese Medicine
2015-2023

Southern Medical University
2023

Nanfang Hospital
2023

Macquarie University
2020

State Council of the People's Republic of China
2017

General Hospital of Jinan Military Command
2014-2016

Jinan Military General Hospital
2011-2015

Given the importance of aggregation advanced glycation end products (AGEs) and cardiac inflammation in onset progression diabetic cardiomyopathy (DCM), our objective this study was to demonstrate cardioprotective effect mangiferin, an antidiabetic anti-inflammatory agent, on rat model. The DCM model established by a high-fat diet low dose streptozotocin. rats were treated orally with mangiferin (20 mg/kg) for 16 weeks. Serum left ventricular myocardium collected determination inflammatory...

10.1139/cjpp-2015-0073 article EN Canadian Journal of Physiology and Pharmacology 2015-11-03

Intestinal mucositis causes great suffering to cancer patients who undergo chemotherapy and radiotherapy. Owing the uncertain side effects of anticancer drugs attenuate patients' intestinal mucositis, many studies focused on traditional Chinese medicine (TCM). Patchouli alcohol (PA) is an active compound extracted from Pogostemon cablin, has potent gastrointestinal protective effect. However, whether PA effect still unknown. Therefore, we established a rat model via intraperitoneal injection...

10.1016/j.biopha.2020.109883 article EN Biomedicine & Pharmacotherapy 2020-01-28

Dysfunction of the glymphatic system in brain different stages altered glucose metabolism and its influencing factors are not well characterized.

10.4239/wjd.v15.i7.1537 article EN World Journal of Diabetes 2024-07-08

Millettiae speciosae Champ. Leguminosae (MSC), is a well-known Chinese herb traditionally used as food material and medicine for enhancing physical strength. Our preliminary study found that the aqueous extract of this (MSE) had an anti-fatigue effect. In paper, we further separated MSE into total polysaccharides (MSP) supernatant (MSS) by alcohol precipitation, explored which fraction was active its Mice were orally administered with MSP or MSS at doses 200, 400, 800 mg/kg 20 days effect...

10.3390/nu7105422 article EN Nutrients 2015-10-21

Abstract Pogostemonis Herba is a functional food approved in Asian countries. Its major constituent, patchouli alcohol (PA), possesses gastroprotective effect and reported to transform into β-patchoulene (β-PAE) under acidic conditions. To investigate whether β-PAE, the metabolite of PA, has protective on gastrointestinal tract, formation β-PAE by gastric juice anti-ulcerogenic potential against ethanol-induced injury were evaluated. The Results indicated that PA was converted rat juice....

10.1038/s41598-017-05996-5 article EN cc-by Scientific Reports 2017-07-11

Curcumin (CUR), a widely used food additive, is derived mainly from<italic>Curcuma</italic>species that has been applied traditionally for treating hepatocellular carcinoma (HCC).

10.1039/c7fo00484b article EN Food & Function 2017-01-01

Bleomycin (BLM), a family of anti-tumor drugs, was reported to exhibit severe side effects limiting its usage in clinical treatment. Therefore, finding adjuvants that enhance the effect and reduce detrimental BLM is prerequisite. Chrysanthemum indicum, an edible flower, possesses abundant bioactivities; supercritical-carbon dioxide fluid extract from flowers buds C. indicum (CISCFE) have strong anti-inflammatory, anti-oxidant, lung protective effects. However, role CISCFE combined with...

10.3390/ijms18030465 article EN International Journal of Molecular Sciences 2017-02-24

According to the GC-MS analysis, compositional variation was observed between samples of patchouli oil, which an unknown compound identified as patchoulene epoxide (PAO) found only in long-stored whose biological activity still remains unknown. Therefore, present study aimed evaluate potential anti-inflammatory with three vivo inflammatory models: xylene-induced ear edema, acetic acid-induced vascular permeability, and carrageenan-induced paw edema. Further investigation into its underlying...

10.1155/2017/1089028 article EN cc-by Mediators of Inflammation 2017-01-01

Brucea javanica is an important Chinese folk medicine traditionally used for the treatment of dysentery (also known as inflammatory bowel diseases). oil emulsion (BJOE), most common preparation javanica, has a variety pharmacological activities. In this follow-up investigation, we endeavored to illuminate potential benefit BJOE on 2, 4, 6-trinitrobenzenesulfonic acid (TNBS)-induced Crohn's disease (CD) in rats and decipher mechanism action. The result illustrated that significantly reduced...

10.1016/j.biopha.2019.108766 article EN Biomedicine & Pharmacotherapy 2019-03-20

Excessive alcohol consumption can cause serious hepatic injury which is associated with oxidative stress and fatty metabolic disturbance.

10.1039/c8ra02422g article EN cc-by-nc RSC Advances 2018-01-01

Pachymic acid (Pac), a major bioactive constituent of Poria cocos, is an antioxidant that inhibits triglyceride (TG) accumulation. To the best our knowledge, present study investigated for first time whether Pac activated sirtuin 6 (SIRT6) signaling to alleviate oleic (OA)-palmitic (PA)-induced lipid metabolism disorders in mouse primary hepatocytes (MPHs). In study, MPHs challenged with were used test effects on intracellular metabolism. Molecular docking studies performed explore potential...

10.3892/etm.2023.12019 article EN Experimental and Therapeutic Medicine 2023-05-15

Piezoelectric atomization, which breaks liquid into tiny droplets, is widely used in aerospace, medicine, and health. Most research piezoelectric atomizers has increased the atomization amount by improving mechanical structure optimizing vibration characteristics. However, as core component of atomizer to realize using dynamic conical angle effect, micro-tapered hole on atomizing sheet not been deeply studied. To eliminate negative influence uneven burr caused machining process sheet,...

10.3390/app13042572 article EN cc-by Applied Sciences 2023-02-16

β-Patchoulene (β-PAE) is a tricyclic sesquiterpene isolated from patchouli oil. According to our previous study, β-PAE has anti-inflammatory activity in vivo; however, its response still remains unconfirmed vitro. Therefore, this study committed demonstrate the effect of on lipopolysaccharide (LPS)-stimulated RAW264.7 macrophages. results, pre-treatment with significantly decreased protein and messenger RNA (mRNA) levels pro-inflammatory cytokines including tumor necrosis factor-α (TNF-α),...

10.1177/1721727x17714694 article EN cc-by-nc European Journal of Inflammation 2017-06-07

Clerodendranthus spicatus (Thunb.) C.Y.Wu (CS) is commonly used to treat kidney diseases in traditional Chinese medicine for its prominent anti-inflammatory effect and nourishing function kidneys. In this study, aqueous extract of CS was assessed protective on UV-induced skin damage mice. The chemical compositions were determined by HPLC-ESI-MS/MS, which 10 components identified. During the experimental period, (0.9, 1.8, 3.6 g/mL) externally applied shaved dorsal skins mice prior UV...

10.1155/2016/9623957 article EN cc-by Evidence-based Complementary and Alternative Medicine 2016-01-01

Dynamic mesh atomizers have been widely used in various fields because of their compact structure, low energy consumption, and production costs. The finite element method is an important technique to analyze the factors affecting atomization performance dynamic atomizers. However, at present, there a lack decisive solutions basic problems boundary setting terms simulation vibration displacement characteristics under different modes. In this paper, two errors were found Vibration Analysis...

10.3390/app13106293 article EN cc-by Applied Sciences 2023-05-21

Abstract We report a rare case of tetralogy Fallot associated with anomalous origin the left pulmonary artery from aorta and aortopulmonary window. Successful one-stage total correction was performed under cardiopulmonary bypass, including implantation artery, repair window, Fallot. The patient experienced an uneventful postoperative course asymptomatic at one-year follow-up. (J Card Surg 2012;27;:112–114)

10.1111/j.1540-8191.2011.01356.x article EN Journal of Cardiac Surgery 2011-12-11
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