A5075604242- Mechanical Circulatory Support Devices
- Cardiac Structural Anomalies and Repair
- Transplantation: Methods and Outcomes
- Cardiac Arrest and Resuscitation
- Heart Failure Treatment and Management
- Renal Transplantation Outcomes and Treatments
- Cardiac pacing and defibrillation studies
- Dialysis and Renal Disease Management
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Viral Infections and Immunology Research
- Acute Kidney Injury Research
- Pneumocystis jirovecii pneumonia detection and treatment
- Chronic Kidney Disease and Diabetes
- Nutrition and Health in Aging
- Cardiovascular Function and Risk Factors
- Tissue Engineering and Regenerative Medicine
- Heart Rate Variability and Autonomic Control
- Health, Medicine and Society
- Nosocomial Infections in ICU
- Aortic Disease and Treatment Approaches
- Congenital Heart Disease Studies
- Cardiovascular and exercise physiology
- Cardiac Valve Diseases and Treatments
- Organ Transplantation Techniques and Outcomes
- Fuel Cells and Related Materials
NewYork–Presbyterian Hospital
2015-2025
Columbia University
2008-2025
Columbia University Irving Medical Center
2015-2025
New York Hospital Queens
2018-2025
Azienda Ospedaliera di Desio e Vimercate
2024
Texas Health Dallas
2022-2024
Presbyterian Hospital
2021
Society of Thoracic Surgeons
2017
Valve (United States)
2017
Emory and Henry College
2017
Background. Systemic amyloidosis complicated by heart failure is associated with high cardiovascular morbidity and mortality. Heart transplantation for patients systemic controversial due to recurrence of disease in the transplanted organ or progression other organs. Methods. All referred transplant evaluation from 1997 2004 were included this retrospective cohort analysis. An interdisciplinary protocol cardiac using extended-donor criteria organs, followed 6 months either high-dose...
Cardiac allograft vasculopathy (CAV) causes impaired blood flow in both epicardial vessels and microvasculature remains a leading cause of posttransplant morbidity mortality. This study examined the prognostic value outcomes CAV, assessed by <sup>13</sup>N-ammonia PET/CT myocardial perfusion imaging heart transplant recipients. <b>Methods:</b> invasive coronary angiography (ICA) were graded using validated scales. CAV progression was intrapatient sequences: baseline ICA, interval with...
ABSTRACT Background Since the 2018 allocation system change in heart transplantation (HT), ischemic times have increased, which may be associated with peri‐operative and post‐operative complications. This study aimed to compare ischemia reperfusion injury (IRI) hearts preserved using ice‐cold storage (ICS) Paragonix SherpaPak TM Cardiac Transport System (CTS). Methods From January 2021 June 2022, consecutive endomyocardial biopsies from 90 HT recipients were analyzed by a cardiac pathologist...
Abstract Aims Acute heart failure (HF) is associated with muscle mass loss, potentially leading to overestimation of kidney function using serum creatinine‐based estimated glomerular filtration rate (eGFR sCr ). Cystatin C‐based eGFR CysC ) less dependent. Changes in the difference between and may reflect loss. We investigated its association clinical outcomes acute HF patients. Methods results A post hoc analysis was performed 841 patients enrolled three trials: Diuretic Optimization...
Chronic systolic heart failure (HF) with acute decompensation can result in cardiogenic shock (CS) requiring short-term mechanical circulatory support. We sought to identify predictors of survival for decompensated HF (ADHF) patients veno-arterial extracorporeal membrane oxygenation (VA-ECMO). Patients >18 years old treated at our institution VA-ECMO from 2009 2018 ADHF CS were studied. Demographic, hemodynamic, and echocardiographic data collected. The primary outcome was discharge....
Previous data report that fibroblast growth factor-2 (FGF-2)-derived peptide FREG potently inhibits FGF-2-dependent angiogenesis in vitro and vivo. Here, we show up to 70% invasion/migration of smooth muscle melanoma cells. Such inhibition is mediated by platelet-derived factor-receptor-α (PDGF-Rα); fact, proliferation migration were restored upon PDGF-Rα neutralization. Further experiments demonstrated interacts with both vivo stimulates its phosphorylation. We have previously shown...
ABSTRACT Background There have been limited reports on immunosuppression strategies and outcomes in dual organ heart transplant populations, primarily from before the 2018 United Network for Organ Sharing (UNOS) allocation policy change. Recent data suggested that with heart–lung heart–liver transplants remained comparable new era, yet heart–kidney recipients worse 1‐year survival. Methods This single‐center retrospective study evaluated adult heart–kidney, heart–liver, September 2019 to May...
Background: Dietary nitrate consumption is associated with cardiometabolic health in many but not all studies. The enterosalivary nitrate-nitrite-nitric oxide (NO 3 - NO 2 NO) pathway requires the oral microbiome for production (a signaling molecule beneficial to health) following intake. We hypothesize that modifies benefits of Methods: analyzed cross-sectional data from 657 ORGINS participants. intakes and alternative healthy eating index (AHEI) scores were calculated food frequency...
Abstract Background and Aims A decline in cognitive function, with a spectrum ranging from mild impairment to dementia (CI-D), is common patients chronic kidney diseases (CKD), rendering them frailer. Whether the coexistence of CKD CI-D increases health risk profile remains unclear. Our work aims clarify how this association adverse outcomes for (stages 3-5). Method This retrospective observational cohort study was conducted on 3-5) Global Collaborative Network (GCN) TriNetX research...
ABSTRACT Background Limited research has compared the relative risks and benefits different statins have after heart transplantation (HT). Method We hypothesize that higher statin intensity is associated with a smaller degree of allograft intimal thickening on intravascular ultrasound (IVUS) at 1‐year post‐HT. Allograft intima‐media thickness (IMT) first annual IVUS was retrospectively in patients initiated low‐intensity (pravastatin 20 mg daily) versus moderate‐intensity (atorvastatin...
Background: In the last 20 years a growing literature has highlighted role of social and cultural activities in fostering individual community well-being. The Covid-19 pandemic had an important impact on individuals communities given lockdown policies enacted, causing unexpected forced abandonment these activities. Aims: present work investigates caused by consequent suspension all associated opportunities for young elderly subjective Methods: We undertook cross-sectional survey January 2020...
ABSTRACT Background and hypothesis Mild cognitive impairment dementia (CI) are common in patients with CKD. We aim to clarify whether how CKD CI coexistence increases adverse health outcomes. Methods This retrospective observational cohort study was conducted on (stages 3–5) from the TriNetX platform. without pre-existing were included 115 healthcare organizations, their outcomes compared. The two cohorts propensity score matched (PSM) for age, sex, ethnicity, comorbidities, BMI, blood...