- Parasites and Host Interactions
- Obstructive Sleep Apnea Research
- Neuroscience of respiration and sleep
- Global Maternal and Child Health
- Parasite Biology and Host Interactions
- Malaria Research and Control
- Zoonotic diseases and public health
- Cardiovascular Disease and Adiposity
- Cardiovascular and Diving-Related Complications
- Sleep and related disorders
- Mosquito-borne diseases and control
- Global Health and Surgery
- Parasitic infections in humans and animals
- Sleep and Wakefulness Research
- Helminth infection and control
- Travel-related health issues
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Viral Infections and Outbreaks Research
- Sepsis Diagnosis and Treatment
- Global Health and Epidemiology
- Climate Change and Health Impacts
- Congenital Anomalies and Fetal Surgery
- Global Health Workforce Issues
- Circadian rhythm and melatonin
- Child Nutrition and Water Access
Southeast University
2024
National Institute for Parasitic Diseases
2014-2024
National Health and Family Planning Commission
2017-2023
Shanghai Jiao Tong University
2015-2021
Shanghai Sixth People's Hospital
2016-2021
Hospital for Tropical Diseases
2019-2021
National Science and Technology Council
2019-2021
Fudan University
2019-2020
Center for Disease Control
2012-2020
Chinese Center For Disease Control and Prevention
2010-2020
This report presented the endemic status of schistosomiasis in People's Republic China at a national level 2015, and analyzed data collected from prevention control system 457 surveillance sites. Among 12 provinces (municipality, autonomous region) for japonica P. R. China, 5 region), i.e., Shanghai, Zhejiang, Fujian, Guangdong Guangxi, had achieved transmission interruption, 7 Sichuan, Yunnan, Jiangsu, Hubei, Anhui, Jiangxi Hunan by end 2015. There were 453 counties (city, district)...
Abstract Few clinical studies have explored altered urinary metabolite levels in patients with obstructive sleep apnea (OSA). Thus, we applied a metabolomics approach to analyze metabolites three groups of participants: polysomnography (PSG)-confirmed OSA, simple snorers (SS) and normal subjects. Ultra-performance liquid chromatography coupled quadrupole time-of-flight mass spectrometry gas were used. A total 21 31 differentially expressed the SS OSA groups, respectively. Patients had 18...
Several cross-sectional studies have reported associations between oral diseases and obstructive sleep apnea (OSA). However, there been no reports regarding the structure composition of microbiota with simultaneous evaluation potential perturbed metabolic profiles in pediatric OSA.An integrated approach, combining metagenomics based on high-throughput 16S rRNA gene sequencing, metabolomics ultra-performance liquid chromatography coupled quadrupole time-of-flight mass spectrometry gas...
The high cost and low availability of polysomnography (PSG) limits the timely diagnosis OSA. Herein, we developed validated a simple-to-use nomogram for predicting We collected analyzed cross-sectional data 4162 participants with suspected OSA, seen at our sleep center between 2007 2016. Demographic, biochemical anthropometric data, as well parameters were obtained. A least absolute shrinkage selection operator (LASSO) regression model was used to reduce dimensionality, select factors,...
Previous studies have reported the effects of obstructive sleep apnea (OSA) and cardiometabolic disorders on cardiovascular disease (CVD), but associations between biomarkers two cardinal features OSA (chronic intermittent hypoxia fragmentation) their interactions CVD in populations remain unclear. A total 1727 subjects were included this observational study. Data overnight polysomnography parameters, biochemical biomarkers, anthropometric measurements collected. Metabolic syndrome (MS),...
Obstructive sleep apnea (OSA) is independently associated with dyslipidemia. Previous studies have demonstrated that fragmentation can impair lipid metabolism. The present study aimed to identify whether dyslipidemia, in a large-scale, clinic-based consecutive OSA sample. This cross-sectional was conducted among 2,686 patients who underwent polysomnography (PSG) for suspicion of from January 2008 2013 at the laboratory. Multivariate regression analyses were performed evaluate independent...
Schistosoma infection in snails can be monitored by microscopy or indirectly sentinel mice. As both these approaches miss infections, more sensitive tests are needed, particularly low-level transmission settings. In this study, loop-mediated isothermal amplification (LAMP) technique, designed to detect a specific 28S ribosomal japonicum (Sj28S) gene with high sensitivity, was compared using snail samples from 51 areas endemic for schistosomiasis five Chinese provinces. addition, the results...
This report presents the endemic status of schistosomiasis in People's Republic China at national level 2016, and analyzes data collected from prevention control system 454 surveillance sites. Among 12 provinces (municipality autonomous region) japonica P. R. China, 5 region), i.e., Shanghai, Zhejiang, Fujian, Guangdong Guangxi, had achieved elimination, 7 Sichuan, Yunnan, Jiangsu, Hubei, Anhui, Jiangxi Hunan transmission by end 2016. There are 451 counties (cities, districts) covering 257...
Eosinophilic meningitis due to rat lungworm, Angiostrongylus cantonensis, is a global public health concern. Human cases and outbreaks have occurred in the new endemic areas, including South America Spain. The growing genetic data of A. cantonensis provides unique opportunity explore spread pattern parasite. Eight more mitochondrial (mt) genomes were sequenced by present study. phylogeny Bayesian inference showed six clades (I-VI) determined network analysis. A total 554 mt or fragments,...
Background Despite significant, steady progress in schistosomiasis control the People's Republic of China over past 50 years, available data suggest that disease has re-emerged with several outbreaks acute infections early new century. In response, a integrated strategy was introduced. Methods This retrospective study conducted between Jan 2005 and Dec 2012, to explore effectiveness implemented by national program since 2004. Results A total 1,047 cases were recorded an annual reduction...
Obstructive sleep apnea (OSA) is thought to be associated with dyslipidemia. However, differences concerning dyslipidemia during rapid eye movement (REM) and non-REM (NREM) have yet determined. This study was designed explore the association between lipid profiles OSA REM or NREM sleep. a clinical cohort. A total of 2,619 participants at least 30 minutes were included. Sleep variables fasting [total cholesterol (TC), triglycerides (TG), low-density lipoprotein (LDL-C), high-density (HDL-C),...
Zimbabwe, located in Southern Africa, faces a significant public health challenge due to schistosomiasis. We investigated this issue with emphasis on risk prediction of schistosomiasis for the entire population. To end, we reviewed available data Zimbabwe from literature search covering 1980-2022 period considering potential impact 26 environmental and socioeconomic variables obtained sources. studied population requiring praziquantel regard whether or not mass drug administration (MDA) had...
Abstract Metabolic disorders have been separately associated with obstructive sleep apnea syndrome (OSAS) and smoking. However, no study has examined their interactions metabolic parameters, including insulin resistance dyslipidemia. To investigate whether the combination of OSAS smoking results in an additive detriment disorder we enrolled consecutive adult men during 2014–2015. Fasted blood samples were taken to determine glucose, insulin, lipid levels. A questionnaire item on pack-year...