A5101532529- Obstructive Sleep Apnea Research
- Neuroscience of respiration and sleep
- Advanced Sensor and Energy Harvesting Materials
- Advanced biosensing and bioanalysis techniques
- Vibration Control and Rheological Fluids
- Nanomaterials and Printing Technologies
- Dielectric materials and actuators
- Biosensors and Analytical Detection
- Sleep and related disorders
- Cardiovascular and Diving-Related Complications
- Sleep and Wakefulness Research
- Advanced Biosensing Techniques and Applications
- Cardiovascular Disease and Adiposity
- Dendrimers and Hyperbranched Polymers
- Soft Robotics and Applications
- RNA Interference and Gene Delivery
- Quantum Dots Synthesis And Properties
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Cancer Mechanisms and Therapy
- Nanoparticle-Based Drug Delivery
- Genetic factors in colorectal cancer
- Voice and Speech Disorders
- Phytochemicals and Antioxidant Activities
- Restless Legs Syndrome Research
- Antioxidant Activity and Oxidative Stress
Beihang University
2018-2025
General Hospital of Shenyang Military Region
2024
Ji Hua Laboratory
2023
Hebei Medical University
2023
Shanghai Sixth People's Hospital
2015-2022
Shanghai Jiao Tong University
2013-2022
China University of Mining and Technology
2022
Jiangsu Academy of Agricultural Sciences
2018-2022
Ministry of Agriculture and Rural Affairs
2022
People’s Hospital of Rizhao
2021
A new type of biodegradable micelles for glutathione-mediated intracellular drug delivery was developed on the basis an amphiphilic hyperbranched multiarm copolymer (H40-star-PLA-SS-PEP) with disulfide linkages between hydrophobic polyester core and hydrophilic polyphosphate arms. The resulting copolymers were characterized by nuclear magnetic resonance (NMR), Fourier transformed infrared (FTIR), gel permeation chromatography (GPC), differential scanning calorimeter (DSC) techniques....
Currently, the major challenge for cancer treatment is to develop new types of smart nanocarriers that can efficiently retain encapsulated drug during blood circulation and quickly release in tumor cells under stimulation. In this study, dual pH-/light-responsive cross-linked polymeric micelles (CPM) were successfully prepared by self-assembly amphiphilic glycol chitosan-o-nitrobenzyl succinate conjugates (GC-NBSCs) then cross-linking with glutaraldehyde (GA), which was synthesized grafting...
Recent years have witnessed the booming development of transparent flexible electrodes (TFEs) for their applications in electronics and optoelectronic devices. Various strategies thus been developed preparing TFEs with higher flexibility conductivity. However, little work has focused on anisotropic Here, a facile strategy directional liquid transfer is proposed, guided by conical fibers array (CFA), based which silver nanowires (AgNWs) are aligned soft poly(ethylene terephthalate) substrate...
Abstract Few clinical studies have explored altered urinary metabolite levels in patients with obstructive sleep apnea (OSA). Thus, we applied a metabolomics approach to analyze metabolites three groups of participants: polysomnography (PSG)-confirmed OSA, simple snorers (SS) and normal subjects. Ultra-performance liquid chromatography coupled quadrupole time-of-flight mass spectrometry gas were used. A total 21 31 differentially expressed the SS OSA groups, respectively. Patients had 18...
Rationale: Previous genetic studies of obstructive sleep apnea (OSA) have limitations in terms precise case definition, integrated quantitative traits, and interpretation functions; thus, the heritability OSA remains poorly explained. Objectives: To identify novel variants associated with objective sleep-related traits to explore their functional roles. Methods: A genome-wide association study was performed 20,590 Han Chinese individuals (5,438 15,152 control samples). Human samples point...
Hydrogen peroxide-responsive nanomicelles from hyperbranched polymers were developed for effective cancer therapy through enhanced apoptotic cell death.
<h3>Background</h3> Dyslipidaemia is an intermediary exacerbation factor for various diseases but the impact of obstructive sleep apnoea (OSA) on dyslipidaemia remains unclear. <h3>Methods</h3> A total 3582 subjects with suspected OSA consecutively admitted to our hospital centre were screened and 2983 (2422 OSA) included in Shanghai Sleep Health Study. severity was quantified using apnoea–hypopnea index (AHI), oxygen desaturation arousal index. Biochemical indicators anthropometric data...
BACKGROUND Major depressive disorder (MDD) with comorbid anxiety is an intricate psychiatric condition, but limited research available on the degree centrality (DC) between anxious MDD and nonanxious patients. AIM To examine changes in DC values their use as neuroimaging biomarkers non-anxious METHODS We examined 23 patients, 30 28 healthy controls (HCs) using for data analysis. RESULTS Compared HCs, group reported markedly reduced right fusiform gyrus (FFG) inferior occipital gyrus, whereas...
Obstructive sleep apnea (OSA) is independently associated with dyslipidemia. Previous studies have demonstrated that fragmentation can impair lipid metabolism. The present study aimed to identify whether dyslipidemia, in a large-scale, clinic-based consecutive OSA sample. This cross-sectional was conducted among 2,686 patients who underwent polysomnography (PSG) for suspicion of from January 2008 2013 at the laboratory. Multivariate regression analyses were performed evaluate independent...
Solution processes have been widely used for making polymer films in organic photoelectric devices but suffer from difficulties controlling the film formation. Here, by situ characterization triphase contact lines (TCLs) a brush-coating process, we clarify how TCLs affect quality of as-prepared films. By fine-tuning dewetting binary solution (P3HT:PCBM) via different directions, with patterns lead to morphologies. High-quality nanothin larger crystallized sizes and higher orientations were...
Background Obstructive sleep apnea (OSA) causes high morbidity and mortality is independently associated with an increased likelihood of multiple complications. The diagnosis OSA presently time-consuming, labor-intensive inaccessible. Aim This study sought to develop a simple efficient model for identifying in Chinese adult population. Methods In this study, the efficiency Epworth Sleepiness Scale (ESS) new established prediction screening were evaluated test cohort (2,032 participants)...