A5092033595- MicroRNA in disease regulation
- Pancreatic function and diabetes
- Diabetes and associated disorders
- Diabetes Treatment and Management
- Arsenic contamination and mitigation
- Adipokines, Inflammation, and Metabolic Diseases
- Metabolism, Diabetes, and Cancer
- Primary Care and Health Outcomes
- Heavy Metal Exposure and Toxicity
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Peroxisome Proliferator-Activated Receptors
- Atherosclerosis and Cardiovascular Diseases
- Galectins and Cancer Biology
- Environmental Justice and Health Disparities
- Health Systems, Economic Evaluations, Quality of Life
- Circular RNAs in diseases
- Cancer-related molecular mechanisms research
- Chronic Disease Management Strategies
- Diabetes Management and Research
Instituto de Investigación Sanitaria del Principado de Asturias
2024-2025
Gobierno del Principado de Asturias
2023-2024
Abstract Type 1 diabetes is a chronic autoimmune disease which results in inefficient regulation of glucose homeostasis and can lead to different vascular comorbidities through life. In this study we aimed analyse the circulating miRNA expression profile patients with type diabetes, no other associated pathology. For this, fasting plasma was obtained from 85 subjects. Next generation sequencing analysis firstly performed identify miRNAs that were differentially expressed between groups (20...
Abstract Background Previous research has indicated that hypoglycemia during hospitalization is a predictor of unfavorable outcomes in patients with diabetes. However, no studies have examined the long-term impact adults admitted for hyperglycemic crises. The study was aimed to investigate implications hyperosmolar crises, particularly terms all-cause mortality. Methods This retrospective cohort included 170 (82 men [48.2%], median age 72 years) university hospital including pure states and...
Metformin is a well-established drug for the treatment of type 2 diabetes; however, mechanism action has not been well described and many aspects how it truly acts are still unknown. Moreover, regarding in vitro experiments, glycaemic status when metformin used generally considered, which, added to suprapharmacological concentrations that commonly employed research, resulted gaps its action. The aim this study was determine glucose influence cell culture. Considering diabetic retinopathy one...
Searchable abstracts of presentations at key conferences in endocrinology ISSN 1470-3947 (print) | 1479-6848 (online)
This study aims to investigate the differential miRNA expression profile between visceral white adipose tissue and skeletal muscle of people with obesity undergoing bariatric surgery. Skeletal samples 10 controls 38 (50% also type 2 diabetes) surgery were collected. profiles analyzed using Next-Generation Sequencing subsequently validated RT-PCR. Approximately 69% miRNAs showed similar in both tissues, however, 55 preferentially expressed 53 muscle. miR-122b-5p was uniquely identified...
Searchable abstracts of presentations at key conferences in endocrinology ISSN 1470-3947 (print) | 1479-6848 (online)
Searchable abstracts of presentations at key conferences in endocrinology ISSN 1470-3947 (print) | 1479-6848 (online)
Searchable abstracts of presentations at key conferences in endocrinology ISSN 1470-3947 (print) | 1479-6848 (online)