A5067963079- Gastrointestinal Tumor Research and Treatment
- Gastrointestinal disorders and treatments
- Gastric Cancer Management and Outcomes
- Gastrointestinal Bleeding Diagnosis and Treatment
- Pancreatic and Hepatic Oncology Research
- Metastasis and carcinoma case studies
- Esophageal and GI Pathology
- Circular RNAs in diseases
- Eosinophilic Esophagitis
- Cancer-related molecular mechanisms research
- MicroRNA in disease regulation
- Gallbladder and Bile Duct Disorders
- Gastroesophageal reflux and treatments
- Medical Device Sterilization and Disinfection
- Colorectal Cancer Screening and Detection
- 14-3-3 protein interactions
- Cancer-related Molecular Pathways
- Autophagy in Disease and Therapy
- Sarcoma Diagnosis and Treatment
- Nuclear Receptors and Signaling
- Mycobacterium research and diagnosis
- Pancreatitis Pathology and Treatment
- Tumors and Oncological Cases
- DNA Repair Mechanisms
China Medical University
2013-2025
Sheng Jing Hospital
2017-2021
AIMTo analyze the diagnostic value of a circular RNA (circRNA), circ-LDLRAD3, in pancreatic cancer. METHODSExpression levels circ-LDLRAD3 were tested both cells and clinical samples; latter included 30 paired cancer tissues adjacent non-tumorous tissues, 31 plasma samples from patients with cancer, healthy volunteers.Real-time quantitative reverse transcription
There is a lack of consensus on how endoscopic ultrasound (EUS)-guided pseudocyst drainage and necrosectomy should be performed. This survey was carried out amongst members the EUS Journal Editorial Board to describe their practices in performing this procedure. worldwide multi-institutional May 2017. The responses 22-question with respect practice EUS-guided were obtained. Twenty-two endoscopists responded questionnaire as follows: 72.7% (16/22) opinion that lumen-apposing metal stents...
Endoscopic full-thickness resection (EFTR) is a mini-invasive technique for gastric subepithelial tumors originating from the muscularis propria, which enables of and can provide complete basis pathological diagnosis. Gastric fistula closure after EFTR challenge endoscopists. In this study, we introduced with using over-the-scope clip (OTSC) system propria. To evaluate feasibility safety OTSC by retrospective analysis on cases defect propria in our hospital. The patients were selected who...
BACKGROUND Endoscopic full-thickness resection (EFTR) is increasingly used for treating gastrointestinal stromal tumors (GISTs) in the stomach. AIM To compare efficacy, tolerability, and clinical outcomes of EFTR vs surgical (SR) gastric GISTs. METHODS We collected data from patients diagnosed with GISTs who underwent either or SR at our hospital October 2011 to July 2024. Patients were matched a 1:1 ratio based on baseline characteristics tumor clinical-pathological features using...
To identify factors that impact the procedure and treatment outcomes for endoscopic full-thickness resection (EFTR) of gastric submucosal tumors (SMTs).Medical records were collected all patients with SMTs who underwent EFTR procedures in Shengjing Hospital between June 2012 April 2014. The data from each patient reviewed, including gender, age, maximum tumor size on ultrasound (EUS), location stomach, length procedure, pneumoperitoneum during EFTR, cost to close defects, hospital stay after...
The incidence of pancreatic cancer is increasing annually in Asia as a whole. Pancreatic ranks sixth terms all malignant tumors. Circular RNA (circRNA) type non-coding which forms covalently closed continuous loop. CircRNA extensively expressed the cytoplasm, and markedly conservative stable. MicroRNA (miR)-378a-3p human (hsa)_circ_0006215 were detected using reverse transcription-quantitative polymerase chain reaction (RT-qPCR) tissue cells. Western blot analysis SERPINA4 hsa_circ_0006215...
Endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) and biopsy (FNB) are effective techniques that widely used for tissue acquisition. However, it remains unclear how to obtain high-quality specimens. Therefore, we conducted a survey of EUS-FNA FNB determine practice patterns worldwide develop strong recommendations based on the experience experts in field.This was multi-institutional among members International Society EUS Task Force (ISEUS-TF). The administered by E-mail through...
Submucosal tumors (SMTs) are usually discovered fortuitously during routine endoscopy, including various non-neoplastic and neoplastic conditions. Endoscopic ultrasound (EUS) is considered to be the best imaging procedure characterize SMTs determine need for further treatment. In this review, following issues will addressed: The role of EUS in diagnosis SMTs, tissue influence on endoscopic resection techniques SMTs.
Abstract Background Owing to the development of double-balloon enteroscopy (DBE) and video capsule endoscopy (VCE) in recent years, direct visualization entire small intestinal mucosa has become possible. Because nonspecific symptoms anatomic location bowel, diagnosis isolated bowel Crohn’s disease (CD) remains a challenge. The aim this research was explore value DBE for CD situations where routine tests cannot confirm diagnosis. Methods This study included patients with suspected who were...
Abstract Background Ligation-assisted endoscopic enucleation (EE-L) was developed for the pathological diagnosis and resection of small gastrointestinal tumors originating from muscularis propria. The technique combines band ligation enucleation. aim this study to evaluate efficacy safety EE-L in Methods A total 43 patients were eligible inclusion June 2009 2011. Endoscopic first performed force tumor assume a polypoid form with pseudostalk. then until completely enucleated Wound closure...
Esophageal tumors arising in the muscularis propria are difficult to be resected endoscopically using standard electro-surgical techniques, even endoscopic submucosal dissection (ESD) technique appeared recently. Our purpose is investigate efficacy of ultrasound (EUS)-assisted tunnel-type ESD for resection these tumors.A total 17 patients were included this study. A endoscope was used. The tunnel created with triangle knife according technique, about 5 cm proximal lesion. EUS performed...
Abstract Background and aims Endoscopic full-thickness resection (EFTR) is difficult to perform in a retroflexed fashion the gastric fundus. The present study at exploring whether direct EFTR can be simple, effective safe procedure treat intraluminal-growth submucosal tumors originating from muscularis propria. Methods patients with propria fundus treated by between 01 January 2017 September 2018 were retrospectively reviewed. In addition, we analyzed traditional EFTR. differences tumor...
Endoscopic submucosal dissection to treat mucosal and lesions sometimes results in low rates of microscopically margin-negative (R0) resection. full-thickness resection (EFTR) has a high R0 rate allows for the definitive diagnosis treatment selected that are not suitable conventional techniques.To evaluate efficacy safety EFTR using an over-the-scope clip (OTSC).This prospective, single-center, non-randomized clinical trial was conducted at endoscopy center Shengjing Hospital China Medical...
Up till now, there are still controversies about the specific indication of endoscopic resection for small gastric subepithelial tumors (gSETs) originating from muscularis propria. We aimed to investigate safety and postoperative pathology analysis.The patients with primary gSETs propria, treated by in center Shengjing Hospital between January, 2011 September, 2019 were enrolled. The complete rate, adverse events clinicopathological features recorded.A total 936 972 SETs ≤ 2 cm propria...
An innovative ligation-assisted endoscopic enucleation (EE-L) technique was developed for the diagnosis and treatment of esophageal subepithelial lesions (smaller than 12 mm) originating from muscularis propria by combining band ligation techniques. The aim study to evaluate efficacy safety EE-L in propria. Forty-seven 44 patients were treated with between September 2010 2012. lesion first aspirated into transparent cap attached tip endoscope. elastic then released around its base. purpose...
Background and Objectives: Small gastrointestinal stromal tumors (GISTs) are defined as less than 2 cm in diameter, which often found incidentally during gastroscopy. There is controversy regarding the management of small GISTs, a certain percentage GISTs become malignant follow-up. Previous studies used Sanger targeted sequencing have shown that mutation rate significantly lower large tumors. The aim this study was to investigate overall mutational profile including those wild-type tumors,...
Background. Endoscopic ultrasonography- (EUS-) assisted band ligation has been proven to be a safe and effective procedure for the treatment of small gastrointestinal stromal tumors (GISTs) apart from relatively high risk postligation perforation gastric fundus. The aim this study is investigate efficacy hemoclip reinforcement in treating GISTs Method. During standard endoscopy, transparent cap attached endoscopic tip was placed over lesion exert sustained maximal aspiration before rubber...
Since its introduction in the early 1990s, endoscopic ultrasound-assisted fine-needle aspiration (EUS-FNA) has been used for sampling of extraintestinal mass lesions and peri-intestinal lymphadenopathy. Although EUS-FNA is highly accurate, lymphomas can be challenging to diagnose using EUS-FNA. We present case a 60-year-old male who had experienced upper abdominal discomfort 1 month. Computerized tomography (CT) examination revealed multiple soft-tissue shadows located above pancreatic body....
BACKGROUND People with achalasia typically have a thick lower esophageal muscularis propria (LEMP), and peroral endoscopic myotomy (POEM) has been effective in treating most patients. LEMP thickness may be associated the outcomes prognosis after POEM. However, more evidence is needed regarding relationship between patient AIM To assess association thickness, measured using ultrasound (EUS), long-term prognosis, especially relapse, POEM for achalasia. METHODS All medical records, including...
A ligation-assisted endoscopic enucleation (EE-L) technique was developed and evaluated to determine its efficacy safety for treating colorectal submucosal tumours (< 10 mm) originating in the muscularis propria.EE-L used treat 13 patients between January 2011 2014. The tumour sucked into a transparent cap ligated at base by rubber band ligature attached tip of endoscope. With creation pseudo-stalk, then enucleated using dissection wound closed with clips.All [median diameter 6.8 (4-10) mm]...