A5049586063- Gastrointestinal Tumor Research and Treatment
- Gastrointestinal disorders and treatments
- Liver Disease Diagnosis and Treatment
- Pancreatitis Pathology and Treatment
- Gastric Cancer Management and Outcomes
- Diet, Metabolism, and Disease
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Pancreatic and Hepatic Oncology Research
- Sarcoma Diagnosis and Treatment
- Cancer, Lipids, and Metabolism
- Cancer, Hypoxia, and Metabolism
- Diet and metabolism studies
- Lipid metabolism and biosynthesis
Shanghai Jiao Tong University
2025
Shanghai First People's Hospital
2025
China Medical University
2022-2023
Background: The burden of metabolic dysfunction-associated steatotic liver disease (MASLD) is increasing, yet there little regional understanding in the Western Pacific. This study aims mainly to report latest MASLD and trends Pacific region for period 1990-2021.
Metabolic dysfunction-associated steatotic liver disease (MASLD) is a common chronic disorder mainly caused by an imbalance in lipid homeostasis. Y-box binding protein 1 (YBX1) participates multiple pathophysiological processes, including embryonic development, tissue repair, disorders, and energy metabolism. The objective of this study to investigate the mechanisms underlying MASLD characterize role YBX1 MASLD. A positive correlation between hepatic expression using single-cell sequencing...
Gastrointestinal stromal tumors (GISTs) with a diameter of < 2 cm are called small GISTs. Currently, endoscopic ultrasound (EUS) is widely used as regular follow-up method for GISTs, which can also provide preliminary basis judging the malignancy potential lesions. However, there no studies on accuracy EUS to assess malignant GISTs.To evaluate efficacy in diagnosis and risk assessment GISTs.We collected data from patients GISTs who were admitted Shengjing Hospital China Medical University...
Background and Objectives: Small gastrointestinal stromal tumors (GISTs) are defined as less than 2 cm in diameter, which often found incidentally during gastroscopy. There is controversy regarding the management of small GISTs, a certain percentage GISTs become malignant follow-up. Previous studies used Sanger targeted sequencing have shown that mutation rate significantly lower large tumors. The aim this study was to investigate overall mutational profile including those wild-type tumors,...
<title>Abstract</title> <bold>Purpose</bold>Malignant tumour cell proliferation has high nutritional requirements and leads to nutrient depletion in local tissues. Metabolic reprogramming under stress is essential for malignant proliferation. Proline metabolism contributes cancer invasion, but the underlying mechanisms remain unclear. The aim of this study was investigate whereby proline maintains hepatocellular carcinoma (HCC) proliferation.<bold>Methods</bold>The Cancer Genome Atlas...
Background: Small gastrointestinal stromal tumors (GISTs) are defined as less than 2 cm in diameter, which often found incidentally during gastroscopy. There is controversy regarding the management of small GISTs and a certain percentage become malignant follow-up. Previous studies have shown that mutation rate significantly lower large used Sanger targeted sequencing. The aim this study was to investigate overall mutational profile GISTs, including those wild-type tumors, using whole exome...