A5070303713- Anesthesia and Neurotoxicity Research
- Bacterial Genetics and Biotechnology
- Anesthesia and Sedative Agents
- Intensive Care Unit Cognitive Disorders
- Bacteriophages and microbial interactions
- Food Quality and Safety Studies
- CRISPR and Genetic Engineering
- Marine Sponges and Natural Products
- Food composition and properties
- Pharmacological Effects of Natural Compounds
- RNA Research and Splicing
- Ginger and Zingiberaceae research
- Plant Reproductive Biology
- RNA regulation and disease
- Antibiotic Resistance in Bacteria
- Genetic Mapping and Diversity in Plants and Animals
- Bacterial Identification and Susceptibility Testing
- RNA and protein synthesis mechanisms
- Escherichia coli research studies
- Synthesis and Biological Activity
- Bioinformatics and Genomic Networks
- bioluminescence and chemiluminescence research
- Freezing and Crystallization Processes
- Microbial Natural Products and Biosynthesis
- Wheat and Barley Genetics and Pathology
East China University of Science and Technology
2017-2025
Oil Crops Research Institute
2023
Chinese Academy of Agricultural Sciences
2023
Ministry of Agriculture and Rural Affairs
2023
Huazhong Agricultural University
2023
Guangzhou University of Chinese Medicine
2021
Affiliated Eye Hospital of Wenzhou Medical College
2021
Wenzhou Medical University
2021
Rutgers, The State University of New Jersey
2014-2016
Rutgers New Jersey Medical School
2014
Propofol is a general anesthetic widely used in surgical procedures, including those pregnant women. Preclinical studies suggest that propofol may cause neuronal injury to the offspring of primates if it administered during pregnancy. However, unknown whether changes would lead long-term behavioral deficits offspring. In this study, (0.4 mg/kg/min, IV, 2 h), saline, or intralipid solution was rats on gestational day 18. We detected increased levels cleaved caspase-3 fetal brain at 6 h after...
The antitumor drug candidate, loonamycin, was isolated from Nocardiopsis flavescens NA01583 and exerts its activity by inhibiting topoisomerase I activity. However, the current production levels of loonamycin are insufficient for further research. To address this limitation, a liquid fermentation method developed, optimizing both conditions medium components. This optimization increased 1 mg/mL on agar plate to 602.32 in shake flask ultimately 532.51 5-L bioreactor. Exogenous addition...
Heterosis refers to the better performance of cross progeny compared with inbred parents, and its utilization contributes greatly agricultural production. Several hypotheses have been proposed explain heterosis mainly including dominance, over-dominance (or pseudo-overdominance) epistasis. However, systematic dissection verification these are rarely documented. Here, comparison level across different traits showed that strong composite (such as yield) could be attributed multiplicative...
Purpose: Retinal pigment epithelium (RPE) cell proliferation is precisely regulated to maintain retinal homoeostasis. Microphthalmia-associated transcription factor (MITF), a critical in RPE cells, has two alternatively spliced isoforms: (+)MITF and (−)MITF. Previous work shown that (−)MITF but not inhibits proliferation. This study aims investigate the role of long non-coding RNA (lncRNA) nuclear-enriched abundant transcript 1 (NEAT1) regulating MITF splicing hence cells. Methods: Mouse...
Small colony variants (SCVs) are a commonly observed subpopulation of bacteria that have small size and distinctive biochemical characteristics. SCVs more resistant than the wild type to some antibiotics usually cause persistent infections in clinic. SCV studies been very active during past 2 decades, especially Staphylococcus aureus SCVs. However, fewer on Escherichia coli exist, so we studied an E. experiment involving deletion yigP locus. PCR DNA sequencing revealed was attributable...
Objective To explore the influence of biological characteristics on yield Amomum villosum Lour. and longiligulare T. L. Wu, to find an effective pollen viability evaluation method storage solve problem low plants. Methods Five germplasm plants were used investigate effects phenological phase, viability, stigma receptivity natural artificial fruit set. Results Wu showed late flowering, its pollination rate is higher than that In all germplasm, setting are more 3 times under conditions. Fruits...
Objective To establish a Daphnia model of alloxan-induced diabetes. Methods were exposed to three different concentrations alloxan (3, 5, and 10 mmol/L) for 30 minutes. Blood glucose survival rate recorded 72 hours after insult. Sequence analysis phylogenetic inference transporters (GLUT) clustered with the maximum-likelihood method. Using reverse transcription quantitative polymerase chain reaction techniques, we investigated transcriptional changes GLUT at 12 (5 exposure. Results Compared...
Objective To reduce the turnaround time for laboratory diagnosis of bacteremia, feasibility rapid identification and susceptibility testing using samples taken directly from positive blood culture bottles was evaluated. Methods The growth microorganisms in screened by BACTEC 9000 system. 65 containing gram-negative bacteria were adopted to test. Culture fluid injected into BD SST vacutainer centrifuged pellet cells. After collecting required McFarland units, they cultured on Phoenix 100...