A5078121541- Glycosylation and Glycoproteins Research
- Electrochemical sensors and biosensors
- Analytical Chemistry and Sensors
- Electrochemical Analysis and Applications
- Cancer, Lipids, and Metabolism
- Bladder and Urothelial Cancer Treatments
- Analytical Methods in Pharmaceuticals
- Galectins and Cancer Biology
- Pancreatic function and diabetes
- Biochemical Analysis and Sensing Techniques
- Polysaccharides and Plant Cell Walls
- Monoclonal and Polyclonal Antibodies Research
- Metabolomics and Mass Spectrometry Studies
- Analytical Chemistry and Chromatography
- Lipid Membrane Structure and Behavior
- Diabetes and associated disorders
- Advanced Biosensing Techniques and Applications
- Antibiotics Pharmacokinetics and Efficacy
- Attention Deficit Hyperactivity Disorder
BOKU University
2025
Institute of Chemistry of the Slovak Academy of Sciences
2023-2024
Slovak Academy of Sciences
2023-2024
Slovak University of Technology in Bratislava
2018-2019
Czech Academy of Sciences, Institute of Analytical Chemistry
2018-2019
Institute of Food Science and Technology
2018
In this work, the electrochemical oxidation and subsequent determination of uric acid was investigated using boron-doped diamond electrodes with various B/C ratios (0–2000 ppm).
Bladder cancer (BC) belongs to the most frequent types. The diagnostic process is still long and costly, with a high percentage of false-positive or -negative results. Due cost lack effectiveness, older methods need be supplemented replaced by newer more reliable method. In this regard, proteins glycoproteins pose potential.
Background: Aberrant glycosylation is a hallmark of cancer and thereby has an excellent potential for the discovery novel biomarkers. Impairments in glycan composition lipoproteins impact their functional properties can be associated with various diseases, including cancer. This research still its infancy; however, it lead to development new diagnostic disease stratification approaches as well therapeutic strategies. Therefore, we aimed evaluate anomalies O-glycosylation apolipoprotein C-III...
In present paper, a miniaturized boron-doped diamond electrode (BDDE) was for the first time used as reliable electrochemical sensor within novel voltammetric protocol rapid and simple determination of dipyridamole (DIP). Cyclic studies uncovered that oxidation DIP shown to be irreversible diffusion-controlled process with single well-developed signal at potential +0.45 V in Britton-Robinson buffer pH 3.0. Using suitable experimental conditions, linearity observed concentration ranges...
Changes in protein glycosylation are associated with most biological processes, and the importance of glycomic analysis research disorders is constantly increasing, including neurodevelopmental field. We glycoprofiled sera 10 children attention-deficit hyperactivity disorder (ADHD) matching healthy controls for 3 types samples: whole serum, after depletion abundant proteins (albumin IgG), isolated IgG. The analytical methods used were a lectin-based glycoprotein microarray enabling...
Protein-carbohydrate interactions happen to be a crucial facet of biology, discharging myriad functions. Microarrays have become premier choice discern the selectivity, sensitivity and breadth these in high-throughput manner. The precise recognition target glycan ligands among plethora others is central for any glycan-targeting probe being tested by microarray analyses. Ever since introduction as an elemental tool glycoprofiling, numerous distinct array platforms possessing different...