A5025534203- Cellular Mechanics and Interactions
- Bone Tissue Engineering Materials
- Insect-Plant Interactions and Control
- Parasites and Host Interactions
- Silkworms and Sericulture Research
- Nanoparticle-Based Drug Delivery
- Polymer Surface Interaction Studies
- Bone Metabolism and Diseases
- Silk-based biomaterials and applications
- Metabolomics and Mass Spectrometry Studies
- Forest Insect Ecology and Management
- Graphene and Nanomaterials Applications
- Studies on Chitinases and Chitosanases
- Nuclear Receptors and Signaling
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Parasitic Diseases Research and Treatment
- Titanium Alloys Microstructure and Properties
- Phytochemistry and Bioactive Compounds
- Dendrimers and Hyperbranched Polymers
- Invertebrate Immune Response Mechanisms
- Traditional and Medicinal Uses of Annonaceae
- Chemical Synthesis and Analysis
- ATP Synthase and ATPases Research
- Antibiotic Resistance in Bacteria
- Bone and Dental Protein Studies
Xi'an Jiaotong University
2021-2024
Ministry of Agriculture and Rural Affairs
2021-2024
Southwest University
2021-2024
Jiangsu Institute of Parasitic Diseases
2020-2024
Huaian First People’s Hospital
2019-2022
State Key Laboratory of Silkworm Genomic Biology
2021
Air Force Medical University
2007-2021
Guangdong Pharmaceutical University
2020
University of Kentucky
2018
South Central Minzu University
2014
Macrophages and osteoclasts are both derived from monocyte/macrophage lineage, which plays as the osteoclastic part of bone metabolism. Although they regulated by implant surface nanoarchitecture involved in osseointegration, beneath mechanism has not been simultaneously analyzed a given model their communication with osteoblasts is also blurring. Here, effect topography on lineage osteoclastogenesis subsequent osteogenesis systematically investigated. The nanoporous fabricated titanium...
Ten new triterpene saponins (<b>1</b>–<b>10</b>) have been isolated from the stems of <i>Entada phaseoloides</i>. Their structures were elucidated by spectroscopic analysis and chemical methods. Among these compounds, aglycons <b>6</b>–<b>10</b> are being reported for first time, in this study, including 3<i>β</i>,15<i>α</i>,16<i>α</i>-trihydroxy-11<i>α</i>,12<i>α</i>-epoxy olean-28,13<i>β</i>-olide (<b>6</b>), 3<i>β</i>,15<i>α</i>,16<i>α</i>-trihydroxy-11-oxo-olean-12-en-28-oic acids...
The porous Ti<sub>6</sub>Al<sub>4</sub>V scaffolds with strontium laded nanotube arrays exhibited enhanced bone formation and ingrowth abilities.
Abstract It is of great importance to study the detachment/attachment behaviors cells (cancer cell, immune and epithelial cell), as they are closely related with tumor metastasis, immunoreaction, tissue development at variety scales. To characterize during interaction between substrate, some researchers proposed using cell traction force (CTF) indicator. date, various strategies have been developed measure CTF. However, these methods only realize measurements passive forces on flat cases....
Colon cancer ranks as the third most common malignancy in world. Combination chemotherapy, resorting to electrospun fibrous technology, has been considered a promising strategy exert synergistic effects colon treatment. Herein, we manufactured various pluronic F127 (PF127)-modified meshes with different weight ratios of camptothecin (CPT) and curcumin (CUR). The fluorescence characterization obtained PF127-CPT-meshes, PF127-CUR-meshes, PF127-CPT/CUR-meshes (2:1) showed that CPT CUR were...
Atherosclerosis (AS) is a dominant and growing cause of death disability worldwide that involves inflammation from its inception to the emergence complications. Studies have demonstrated intervention with helminth infections or derived products could modulate host immune response effectively prevent mitigate onset progression inflammation-related diseases. Therefore, understand molecular mechanisms underlying development atherosclerosis, we intervened in ApoE-/- mice maintained on high-fat...
Hookworm is one type of soil-transmitted helminth, which could exert an anti-inflammatory effect in human or animal host, provides a beneficial possibility for the discovery inflammatory-related disease interventions. The identification hookworm-derived molecules urgently needed future translational research. emergence metabolomics has become powerful approach to comprehensively characterize metabolic alterations recent times. Herein, excretory and secretory products (ESPs) were collected...
The color pattern of insects is one the most diverse adaptive evolutionary phenotypes. However, molecular regulation this not fully understood. In study, we found that transcription factor Bm-mamo responsible for black dilute ( bd ) allele mutations in silkworm. belongs to BTB zinc finger family and orthologous mamo Drosophila melanogaster . This gene has a conserved function gamete production silkworms evolved pleiotropic patterns caterpillars. Using RNAi clustered regularly interspaced...
Atherosclerosis (AS) has become the leading cause of cardiovascular disease worldwide. Our previous study had observed that
To investigate the alleviation of
To investigate the polarization of human acute monocytic leukemia THP-1 cells-derived macrophages induced by Nippostrongylus brasiliensis proteins in vitro, so as to provide insights into elucidation mechanisms underlying host immune responses hookworm infections.The in-vitro culture N. was established and maintained laboratory, third- (L3) fifth-stage larvae (L5) were collected under a sterile condition for preparation L3 L5 proteins. The cells established, stimulated with 500 ng/mL PMA...
Stress in the three-dimensional extracellular matrix is one of key cues regulating multiscale biological processes. Thus far, noticeable progress methods and technologies (e.g., micropipette aspiration, AFM, molecule probes) has been made to quantify forces/stresses cell microenvironment at different length scales. Among them, microsphere sensor-based method (MSS-based method) emerged as an advantageous approach over conventional techniques quantifying stress situ vivo cellular...