- Health disparities and outcomes
- Frailty in Older Adults
- Nutrition and Health in Aging
- Dementia and Cognitive Impairment Research
- Older Adults Driving Studies
- Technology Use by Older Adults
- Urban Transport and Accessibility
- Physical Activity and Health
- Body Composition Measurement Techniques
- Hearing Loss and Rehabilitation
- Nutritional Studies and Diet
- Geriatric Care and Nursing Homes
- Noise Effects and Management
- Health and Wellbeing Research
- EEG and Brain-Computer Interfaces
- Chronic Disease Management Strategies
- Aging and Gerontology Research
- Health Systems, Economic Evaluations, Quality of Life
- Functional Brain Connectivity Studies
- Employment and Welfare Studies
- Workplace Health and Well-being
- Psychological and Temporal Perspectives Research
- Optical Imaging and Spectroscopy Techniques
- Telemedicine and Telehealth Implementation
- Health and Well-being Studies
National Center for Geriatrics and Gerontology
2021-2025
Japan Society for the Promotion of Science
2024-2025
Importance Loneliness is suggested to negatively affect physical and mental health influence the development of disability; however, a consensus on relationship between loneliness disability has not been reached. Age-related hearing impairment worsens daily-life activities older adults, association incidence may be influenced by impairment. Objective To examine among adults stratified Design, Setting, Participants This prospective observational cohort study included 5563 community-dwelling...
Cognitive reserve (CR) is a property of the brain that allows for better-than-expected cognitive performance relative to degree change over course life. However, neurophysiological markers CR remain under-investigated. Electroencephalography (EEG) features may function as suitable CR. To assess this, we investigated whether dorsal attention network (DAN) and ventral (VAN) activities, measured during resting-state EEG, moderate relationship between hippocampal volume episodic memory.
Regular physical activity throughout life is generally recommended to prevent dementia; however, there little evidence regarding the association between lifetime and mild cognitive impairment (MCI), which often precedes dementia. This study aimed examine of their transitions with late-life MCI.
Introduction: Maximizing the benefits of physical activity (PA) is important to prevent frailty for a measure this public health issue. This study aimed investigate association timing PA with conversion frailty. Methods: longitudinal observational enrolled total 1,310 community-dwelling Japanese older adults who in National Center Geriatric and Gerontology-Study Syndromes remained as examined population. A checkup was conducted baseline characteristics. Subsequently, objectively measured...
The emergence of disease-modifying treatment options for Alzheimer disease is creating a paradigm shift in strategies to identify patients with mild symptoms primary care settings. Systematic reviews on digital cognitive tests reported that most showed diagnostic performance comparable paper-and-pencil impairment and dementia. However, studies have small sample sizes, fewer than 100 individuals, are based case-control or cross-sectional designs. This study aimed examine the predictive...
Background : We aimed to develop and validate a multivariable model for predicting dropout from community-based going-out program older adults. Methods The National Center Geriatric Gerontology’s Study of Syndromes, with prospective cohort general adults, was employed. A total 5905 adults who were independent in their activities daily living recruited randomly allocated into training, validation, testing data sets 6:2:2 ratio. An outcome defined as dropping out within 180 days. extreme...
The present study developed a simplified decision-tree algorithm for fall prediction with easily measurable predictors using data from longitudinal cohort study: 2520 community-dwelling older adults aged 65 years or participated. Fall history, age, sex, fear of falling, prescribed medication, knee osteoarthritis, lower limb pain, gait speed, and timed up go test were assessed in the baseline survey as predictors. Moreover, recent falls follow-up survey. We created fall-prediction analysis...
Abstract Background Physical frailty accelerates the timing of both subsequent disability and death; however, evidence regarding impact on period from onset to death sex differences this is lacking. The aim study was examine relationship among physical frailty, disability, death, differences. Methods This Japanese cohort included 10,524 community‐dwelling people aged ≥65 years. operationalized by key phenotypes as per Fried's criteria (slowness, weakness, exhaustion, weight loss, low...
<b><i>Introduction:</i></b> The prevalence of hearing and visual impairment (HI VI) dual sensory (DSI), which is a combination both, increasing as the population ages. These impairments are expected to increase cognitive load information processing from vision impair appropriate processing. Although an association between DSI decline has been reported, more detailed study effects on each domain required. This aimed investigate self-reported in community-dwelling older...
Aims For older adults with limited life space and activity, social participation in the neighborhood community is essential to ensure interaction activity levels. This study examined association between onset of disability different spaces activities. Methods The participants were 9513 from a cohort conducted at National Center for Geriatrics Gerontology Study Geriatric Syndromes (NCGG‐SGS). Social was assessed by participating meetings. Life activities evaluated using Activity Mobility...
Early preventive measures against depression have become important with unprecedented global aging. Increase in one's perceived value (PV) may correspond to better mental health outcomes. This cross-sectional observation study aimed clarify whether the PV of adopting new behaviors is associated depressive symptoms. The participants were 5266 community-dwelling older adults aged ≥ 65 years. We developed a questionnaire measure behaviors, specifically activities beneficial for preventing...
This observational prospective cohort study, conducted between September 2015 and February 2019, aimed to investigate the association incidence of disability non-face-to-face interactions among community-dwelling older adults in Japan.