A5078984127- Health disparities and outcomes
- Dementia and Cognitive Impairment Research
- Frailty in Older Adults
- Nutritional Studies and Diet
- Nutrition and Health in Aging
- Blood Pressure and Hypertension Studies
- Physical Activity and Health
- Health Systems, Economic Evaluations, Quality of Life
- Balance, Gait, and Falls Prevention
- Geriatric Care and Nursing Homes
- Cardiovascular Health and Disease Prevention
- Urban Transport and Accessibility
- Older Adults Driving Studies
- Body Composition Measurement Techniques
- Technology Use by Older Adults
- Stroke Rehabilitation and Recovery
- Genetic Associations and Epidemiology
- Sodium Intake and Health
- Diet and metabolism studies
- Chronic Disease Management Strategies
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Health and Wellbeing Research
- Optical Imaging and Spectroscopy Techniques
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Pain Management and Opioid Use
Tohoku Medical Megabank Organization
2022-2025
Tohoku University
2022-2025
General Department of Preventive Medicine
2024
Tohoku University Hospital
2024
Graduate School USA
2023
National Center for Geriatrics and Gerontology
2018-2023
Shinshu University
2021-2022
Abstract Risk factors for hypertension have been emphasized in the Japanese Society of Hypertension Guidelines Management Hypertension. However, large-scale studies on association smoking, potassium excretion, and gamma-glutamyl transferase level with BP population are limited. We conducted a cross-sectional study to examine between risk systolic blood pressure Tohoku Medical Megabank Community-based Cohort Study (23,446 men 38,921 women aged ≥20 years). A model adjusted age, body mass...
Abstract No study, to our knowledge, has constructed a polygenic risk score based on clinical blood pressure and investigated the association of genetic lifestyle risks with home hypertension. We examined associations combined hypertension In cross-sectional study 7027 Japanese individuals aged ≥20 years, we developed body mass index, alcohol consumption, physical activity, sodium-to-potassium ratio, categorized into ideal, intermediate, poor lifestyles. A was target data ( n = 1405) using...
This study examined the association between pain characteristics and incidence of functional disability among community-dwelling older adults. prospective cohort included 4,365 adults (mean age 74.7 years, 53.5% female) living in community settings. Pain characteristics, including severity duration pain, were assessed participants who also underwent monthly follow-up assessment for 24 months based on national long-term care insurance system. Among participants, 2,149 (48.7%) reported...
The present study aimed to examine the prospective associations of physical frailty with future falls and fear falling (FOF) among community-dwelling older adults.A cohort a 48-month follow-up was conducted in Japanese community. Participants were 2469 adults aged 65 years or who completed baseline assessments at intervals 48 ± 2 months. Primary outcomes recent (defined as least one fall within past year) FOF (determined by response "Are you afraid falling?") survey. Physical frailty,...
The purpose of this study was to report the basic profile Miyagi Prefecture part a repeated center-based survey during second period Tohoku Medical Megabank Community-Based Cohort Study (TMM CommCohort Study), as well participants' characteristics based on their participation type in baseline survey.
Background: The relationship between blood cell profiles, including hemoglobin (Hb) levels and inflammatory hematological ratios, mental health problems currently remains unclear. Aim: This study aimed to investigate the profiles issues, depressive state sleep disturbance, while adjusting for potential demographic confounders. Methodology: retrospective, cross-sectional, observational used a population-based medical database from Tohoku Medical Megabank Project with more than 60,000...
Abstract This study aimed to investigate the association of combination birth weight and current body mass index (BMI) with risk hypertension in adulthood. cross-sectional used data from Tohoku Medical Megabank Community-based Cohort Study conducted Japan. A total 10,688 subjects aged ≥20 years were eligible. We calculated least square (LS) means systolic blood pressure (SBP) trend tests performed evaluate linear relationships between categories SBP. also a multivariate logistic regression...
The primary prevention of atrial fibrillation (AF), which increases mortality through complications including stroke and heart failure, is important. Excessive salt intake low potassium are risk factors for cardiovascular disease; however, their association with AF remains inconclusive. This study investigated the between sodium- potassium-related urinary markers prevalence. Data from Tohoku Medical Megabank Project Community-based Cohort Study were used in this cross-sectional study....
Background Natural disasters may have negative health effects on survivors. However, long-term observations this are lacking. Therefore, study investigated the association between degree of housing damage caused by Great East Japan Earthquake (GEJE) and all-cause mortality using data from cohort conducted Tohoku Medical Megabank (TMM) Project in disaster-stricken areas. Methods The community-based TMM which a baseline survey May 2013 to March 2016 collected questionnaires blood urine tests....
Objectives Previous studies have assessed the impact of active smoking on mortality using population-attributable fraction (PAF). However, these not included second-hand (SHS), potentially underestimating smoking’s impact. We compared PAF from alone with PAF, including SHS exposure. Design Prospective cohort study. Setting A community-based study in Japan. Participants 40 796 participants aged ≥20 years. Main outcome measures was defined as inhaling someone else’s cigarette smoke at...
ABSTRACT Objectives Owing to spousal pairs often exhibiting similar health behaviors, this study examined the concordance of cancer screening attendance between spouses using cross‐sectional data from a large biobank in Japan, which included 2022 pairs. Study Design Cross‐sectional study. Methods Self‐administered were collected determine whether participants had undergone for colorectal, gastric, and lung cancers past year. The following two analyses conducted: exposure was husband attended...
Physical frailty is associated with social activity. However, the relationship between physical and levels of engagement other people during activities remains unclear. Thus, we aimed to clarify activity using a taxonomy among community-dwelling older adults in Japan.This cross-sectional observational study analyzed data from 12,788 (7001 women, mean age: 73.8 years, standard deviation = 5.9; range: 60-96 years) National Center for Geriatrics Gerontology-Study Geriatric Syndromes. was...
Abstract Depression is comorbid with somatic diseases; however, the relationship between depressive symptoms and hypertension (HT), a risk factor for cardiovascular events, remains unclear. Home blood pressure (BP) more reproducible accurately predictive of diseases than office BP. Therefore, we focused on home BP investigated whether contributed to future onset HT. This prospective cohort study used data from Tohoku Medical Megabank Community-Cohort Study (conducted in Miyagi Prefecture,...
The present study developed a simplified decision-tree algorithm for fall prediction with easily measurable predictors using data from longitudinal cohort study: 2520 community-dwelling older adults aged 65 years or participated. Fall history, age, sex, fear of falling, prescribed medication, knee osteoarthritis, lower limb pain, gait speed, and timed up go test were assessed in the baseline survey as predictors. Moreover, recent falls follow-up survey. We created fall-prediction analysis...
We examined the association between carotid intima medica thickness (cIMT) and risk factors for atherosclerosis based on Japan Atherosclerosis Society 2022 Prevention Guideline.
Although several studies have shown an inverse association between lung function and hypertension, few examined the hypertension among never-smokers, no study has investigated home hypertension. We associations in a Japanese population.We conducted cross-sectional of 3728 men 8795 women aged 20 years or older living Miyagi Prefecture, Japan. Lung was assessed using forced expiratory volume at 1 s (FEV ) vital capacity (FVC), measured by spirometry. Hypertension defined as casual blood...
This study clarified the patterns of possessing modifiable risk factors dementia that can be corrected by elderly who were primarily determined to have mild cognitive impairment (MCI), and then relationship between retention outcomes from MCI through a 4-year follow-up study. The participants 789 community-dwelling elders ≥65 years old with at baseline. After 4 years, classified into reverters nonreverters, according their function. Repeated measures analysis was performed after imputing...
The aim of this study was to examine cortical thickness changes associated with a multicomponent exercise intervention combining physical and cognitive training in older adults decline. This involved secondary analysis neuroimaging data from randomized controlled trial 280 having decline who were randomly assigned either group (n = 140) that attended weekly 90-minute sessions or health education control 140). performance assessed at the baseline completion (10 months). frontal temporal...
The aim of this study was to examine the association between lifestyle activities, including physical, cognitive, and social Alzheimer's disease (AD) signature cortical thickness, as well mediating role AD thickness in activities cognitive function community-dwelling healthy older adults. Participants were 1026 adults who met inclusion criteria. daily life assessed using a self-reporting questionnaire. determined FreeSurfer software. Cognitive evaluated National Center for Geriatrics...