Jean‐Michel Gonzalez

ORCID: 0000-0001-5772-8236
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About
Contact & Profiles
Research Areas
  • Esophageal and GI Pathology
  • Gastroesophageal reflux and treatments
  • Gastric Cancer Management and Outcomes
  • Pancreatic and Hepatic Oncology Research
  • Dysphagia Assessment and Management
  • Gallbladder and Bile Duct Disorders
  • Gastrointestinal motility and disorders
  • Gastrointestinal disorders and treatments
  • Esophageal Cancer Research and Treatment
  • Bariatric Surgery and Outcomes
  • Pediatric Hepatobiliary Diseases and Treatments
  • Pancreatitis Pathology and Treatment
  • Biliary and Gastrointestinal Fistulas
  • Helicobacter pylori-related gastroenterology studies
  • Neuroendocrine Tumor Research Advances
  • Eosinophilic Esophagitis
  • Colorectal Cancer Screening and Detection
  • Gastrointestinal Tumor Research and Treatment
  • Diverticular Disease and Complications
  • Intestinal Malrotation and Obstruction Disorders
  • Tracheal and airway disorders
  • Clinical Nutrition and Gastroenterology
  • Metastasis and carcinoma case studies
  • Lung Cancer Research Studies
  • Appendicitis Diagnosis and Management

Aix-Marseille Université
2015-2025

Assistance Publique Hôpitaux de Marseille
2015-2025

Hôpital Nord
2016-2025

Hospital Universitario De Cabueñes
2021-2023

Société Française d'Endoscopie Digestive
2019-2022

Lyon Genou Centre Albert Trillat
2021

Hôpital Saint Joseph
2020

Vinci (France)
2019

Délégation Paris 7
2019

Hôpital Beaujon
2019

Abstract Background Pancreatic neuroendocrine tumors (NETs) and intraductal pancreatic mucinous neoplasia (IPMN) with worrisome features are surgically managed. Endoscopic ultrasound (EUS)-guided radiofrequency ablation (RFA) has recently been developed. The safety of EUS-RFA was the primary end point this study, its efficacy secondary point. Methods This a prospective multicenter study that planned to include 30 patients 1-year follow-up either NET < 2 cm or cystic neoplasm (PCN), branch...

10.1055/a-0824-7067 article EN Endoscopy 2019-01-22

Summary of Recommendations 1 ESGE recommends that each center implements a written policy regarding the management iatrogenic perforations, including definition procedures carry higher risk this complication. This should be shared with radiologists and surgeons at center. 2 in case an endoscopically identified perforation, endoscopist reports its size location, image, statement endoscopic treatment has been applied. 3 symptoms or signs suggestive perforation after procedure rapidly carefully...

10.1055/a-1222-3191 article EN Endoscopy 2020-08-11

Gastric peroral endoscopic pyloromyotomy (G-POEM) was introduced for treating refractory gastroparesis.To present a series of patients focussed on clinical mid-term efficacy and predictive outcomes factors.This single centre study 29 operated between January 2014 April 2016, with disturbed gastric emptying scintigraphy (GES) and/or elevated Gastroparesis Cardinal Symptoms Index (GCSI). The procedures were performed as previously described. primary endpoint the at 3 6 months, based GCSI...

10.1111/apt.14132 article EN Alimentary Pharmacology & Therapeutics 2017-05-15

Therapeutic endoscopy has recently evolved into the treatment of complex gastrointestinal (GI) postoperative leakage, especially with over-the-scope clips (OTSC). We describe our 2-year experience 30 patients treated for digestive fistulas using OTSC device.This was a retrospective study conducted on referred GI in two French hospitals. Technical aspects, clinical outcomes and closure rates were recorded.Thirty leaks: 19 (63%) had gastric fistula after laparoscopic sleeve gastrectomy (LSG);...

10.1111/den.12295 article EN Digestive Endoscopy 2014-04-10

Main Recommendations ESGE suggests flexible endoscopic treatment over open surgical as first-line therapy for patients with a symptomatic Zenker’s diverticulum of any size. Weak recommendation, low quality evidence, level agreement 100 %. recommends that emerging treatments diverticulum, such peroral myotomy (Z-POEM) and tunneling, be considered experimental; these should offered in research setting only. Strong against the widespread clinical use transoral incisionless fundoplication (TIF)...

10.1055/a-1171-3174 article EN Endoscopy 2020-05-27

Abstract Background Gastroparesis is a difficult-to-treat motility disorder with poor response to medical therapy. Gastric peroral endoscopic pyloromyotomy (G-POEM) has been offered as novel therapy in the treatment of refractory gastroparesis. We present multicenter case series our experience G-POEM. Methods This an international patients who underwent G-POEM for The severity gastroparesis was assessed by delayed gastric emptying scintigraphy (GES) and elevated cardinal symptoms index...

10.1055/a-0596-7199 article EN Endoscopy 2018-04-12

Most studies on the human microbiota have analyzed stool samples, although a large proportion of absorption nutrients takes place in upper gut tract. We collected samples from different locations along entire gastrointestinal tract six patients who had simultaneously undergone endoscopy and colonoscopy, to perform comprehensive analysis using culturomics with matrix assisted laser desorption ionisation - time flight (MALDI-TOF) identification by metagenomics targeting 16S ribosomal...

10.1186/s12866-018-1304-7 article EN cc-by BMC Microbiology 2018-10-24

Abstract Background and study aims Endoscopic ultrasound-guided radiofrequency ablation (EUS-RFA) for pancreatic neuroendocrine tumors (NETs) intraductal mucinous neoplasia (IPMN) with worrisome features or high-risk stigmata (WF/HRS) has been evaluated in few series short-term outcomes. This studyʼs primary endpoint was to assess the long-term efficacy of EUS-RFA patients NETs cystic neoplasms (PCNs) over at least 3 years. Patients methods Twelve had 14 a mean 13.4-mm size (10–20) 17 tumor...

10.1055/a-1479-2199 article EN cc-by-nc-nd Endoscopy International Open 2021-07-16

Endoscopic ultrasound-guided gastroenterostomy (EUS-GE) using lumen-apposing metal stents (LAMSs) appears to be effective and safe in gastric outlet obstruction (GOO); however, the EUS-GE procedure is not standardized, with use of assisted or direct methods still debated. The aim this study was compare outcomes techniques focusing on an orointestinal drain wireless endoscopic simplified technique (WEST) nonassisted over a guidewire (DTOG).This multicenter European retrospective involving...

10.1055/a-2119-7529 article EN Endoscopy 2023-06-28

Background and study aims We aimed to identify risk factors salvage technique for technical failures of endoscopic ultrasound-guided choledochoduodenostomy (EUS-CDS) evaluate the short long-term consequences in patients with biliary obstruction. Patients methods This retrospective multicenter included EUS-CDS from 2018 2024. Cases were defined as failure classified follow: type1 (digestive-flange mispositioned), type2 (biliary-flange type3 (stent deployment failure), type4 (catheter-LAMS...

10.1055/a-2541-2973 article EN Endoscopy 2025-02-17

There are no existing data in the literature on learning curve of French interns colonoscopy or comparison between different frequencies training modalities. We aimed to assess number procedures required for residents hepatogastroenterology achieve competency colonoscopy. The primary outcome was achieving greater than 90% cecal intubation rate (CIR90) using Learning Curve-Cumulative Summation (LC-CUSUM) method. Participants with over 80 were categorized into intensive and progressive groups....

10.1186/s12909-025-06924-2 article EN cc-by-nc-nd BMC Medical Education 2025-03-11

Gastroparesis is a chronic functional syndrome that affects 4 % of the population [1] with an impact on quality life. The etiologies include diabetic, post gastric surgery, and idiopathic forms [2]. Diagnosis based symptoms related to emptying endoscopy scintigraphy. therapeutic options, including drugs (metoclopramide, erythrocin), surgery (pyloroplasty, electrical stimulation), or (botulinum toxin injection) remain insufficiently effective [3] [4] [5] [6] [7]. However, physiopathology...

10.1055/s-0034-1391821 article EN Endoscopy 2015-03-11

Data on the long-term outcomes of gastric peroral endoscopic myotomy (G-POEM) for refractory gastroparesis are lacking. We report results a large multicenter follow-up study G-POEM gastroparesis.This was retrospective all operations performed in seven expert French centers with at least 1 year follow-up. The primary endpoint 1-year clinical success rate, defined as 1-point improvement Gastroparesis Cardinal Symptom Index (GCSI).76 patients were included (60.5 % women; age 56 years). median...

10.1055/a-1205-5686 article EN Endoscopy 2020-06-23

Objectives A single‐use duodenoscope (SUD) has been recently developed to overcome issues with endoscopic retrograde cholangiopancreatography (ERCP)‐related cross‐infections. The aim was evaluate SUD safety and performance in a prospective multi‐centre study. Methods All consecutive patients undergoing ERCP six French centers were prospectively enrolled. procedures performed the SUD; case of failure, operators switched reusable duodenoscope. Study outcomes successful completion procedure...

10.1111/den.13965 article EN Digestive Endoscopy 2021-03-05

Background and study aims The aim of this was to validate the COlorectal NEoplasia Classification Choose Treatment (CONECCT) classification that groups all published criteria (including covert signs carcinoma) in a single table. Patients methods For multicenter comparative an expert endoscopist created image library (n = 206 lesions; from hyperplastic deep invasive cancers) with at least white light Imaging chromoendoscopy images (virtual ± dye based). Lesions were resected/biopsied assess...

10.1055/a-1613-5328 article EN cc-by-nc-nd Endoscopy International Open 2022-01-01

Boerhaave syndrome (BS) is a spontaneous esophageal perforation which carries high mortality. Surgical treatment well established, but the development of interventional endoscopy has proposed new therapies. We expose our experience in Gastrointestinal and Endoscopy Unit. With retrospective, observational, open-label, single center, consecutive case series. All patients diagnosed with BS who were managed center included. Treated conservatively, endoscopically or surgically, according to their...

10.5946/ce.2017.043 article EN cc-by-nc Clinical Endoscopy 2017-09-20
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